15P Enhancement Platform for immune Cells (EPiC): invIOs’s innovative cell-therapy platform for creating personalized cancer treatments von Kuttke, M., Gugenberger, R., Thell, K., Bischof, S., Peball, B., Muehleisen, H., Urban, M., Gapp, B., Bugajska-Schretter, A., Halfmann, A., Morley, P., Dohnal, A.

Volltext

Genome-wide genetic screening with chemically mutagenized haploid embryonic stem cells von Forment, JV, Herzog, M, Coates, J, Konopka, T, Gapp, BV, Nijman, SM, Adams, DJ, Keane, TM, Jackson, SP

Volltext bestellen

Whole exome sequencing identifies genetic variants in inherited thrombocytopenia with secondary qualitative function defects von Johnson, Ben, Lowe, Gillian C, Futterer, Jane, Lordkipanidzé, Marie, MacDonald, David, Simpson, Michael A, Sanchez-Guiú, Isabel, Drake, Sian, Bem, Danai, Leo, Vincenzo, Fletcher, Sarah J, Dawood, Ban, Rivera, José, Allsup, David, Biss, Tina, Bolton-Maggs, Paula Hb, Collins, Peter, Curry, Nicola, Grimley, Charlotte, James, Beki, Makris, Mike, Motwani, Jayashree, Pavord, Sue, Talks, Katherine, Thachil, Jecko, Wilde, Jonathan, Williams, Mike, Harrison, Paul, Gissen, Paul, Mundell, Stuart, Mumford, Andrew, Daly, Martina E, Watson, Steve P, Morgan, Neil V

Volltext

Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line von Essletzbichler, Patrick, Konopka, Tomasz, Santoro, Federica, Chen, Doris, Gapp, Bianca V, Kralovics, Robert, Brummelkamp, Thijn R, Nijman, Sebastian M B, Bürckstümmer, Tilmann

Volltext

The research gap in chronic paediatric pain: A systematic review of randomised controlled trials von Boulkedid, R., Abdou, A.Y., Desselas, E., Monégat, M., Leeuw, T.G., Avez‐Couturier, J., Dugue, S., Mareau, C., Charron, B., Alberti, C., Kaguelidou, F., Bali, Donjeta, Hoxha(Qosja), Alketa, Kola, Ermira, Talvik, Inga, Andrieu‐Galien, Juliette, Annequin, Daniel, Blanchet, Romy, Desguerre, Isabelle, Fournier‐Charrière, Elisabeth, Tourniaire, Barbara, Wood, Chantal, Neubert, Antje, Trollmann, Regina, Wimmer, Stefan, Garini, Eleana, Mammi, Panagoula, Allegretti, Marcello, Bellagamba, Ornella, Benini, Franca, Bonifazi, Donato, Caprino, Daniela, Ceci, Adriana, Congedi, Sabrina, Craig, Francesco, Dallorso, Sandro, Divisic, Antuan, Felisi, Mariagrazia, Gentile, Marco, De Giacomo, Andrea, Lundin, Rebecca, Manfredini, Luca, Mangiarini, Laura, Matera, Emilia, Margari, Lucia, Mazza, Alessandro, Pace, Virgilio, Di Pede, Chiara, Giuseppina Petruzzelli, Maria, Ruffini, Pieradelchi, Tagliavacca, Luigina, Traverso, Maria, Mensink, Maarten O, Tibboel, Dick, Wildt, Saskia N, Zanden, Tjitske, Pasqua, Oscar Della, Healy, Paul

Volltext

A generic strategy for CRISPR-Cas9-mediated gene tagging von Lackner, Daniel H., Carré, Alexia, Guzzardo, Paloma M., Banning, Carina, Mangena, Ramu, Henley, Tom, Oberndorfer, Sarah, Gapp, Bianca V., Nijman, Sebastian M.B., Brummelkamp, Thijn R., Bürckstümmer, Tilmann

Volltext

Evaluation of a whole blood remote platelet function test for the diagnosis of mild bleeding disorders von Dovlatova, N., Lordkipanidzé, M., Lowe, G. C., Dawood, B., May, J., Heptinstall, S., Watson, S. P., Fox, S. C.

Volltext

Quantitative genetic screening reveals a Ragulator-FLCN feedback loop that regulates the mTORC1 pathway von De Zan, Erica, van Stiphout, Ruud, Gapp, Bianca V, Blomen, Vincent A, Brummelkamp, Thijn R, Nijman, Sebastian M B

Volltext

A novel thromboxane A2 receptor N42S variant results in reduced surface expression and platelet dysfunction von Nisar, Shaista P., Lordkipanidzé, Marie, Jones, Matthew L., Dawood, Ban B., Murden, Sherina, Cunningham, Margaret R., Mumford, Andrew D., Wilde, Jonathan T., Watson, Steve P., Mundell, Stuart J., Lowe, Gillian C.

Volltext

Epigenetic regulation in neurodevelopment and neurodegenerative diseases von Gapp, K, Woldemichael, B.T, Bohacek, J, Mansuy, I.M

Volltext

Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new... von de Leeuw, Thomas G, Mangiarini, Laura, Lundin, Rebecca, Kaguelidou, Florentia, van der Zanden, Tjitske, Pasqua, Oscar Della, Tibboel, Dick, Ceci, Adriana, de Wildt, Saskia N

Volltext

Predictive value of cardiovascular parameters in twin‐to‐twin transfusion syndrome von Gapp‐Born, E., Sananes, N., Weingertner, A. S., Guerra, F., Kohler, M., Fritz, G., Viville, B., Gaudineau, A., Langer, B., Sauleau, E., Nisand, I., Favre, R.

Volltext

A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer von Muellner, Markus K, Uras, Iris Z, Gapp, Bianca V, Kerzendorfer, Claudia, Smida, Michal, Lechtermann, Hannelore, Craig-Mueller, Nils, Colinge, Jacques, Duernberger, Gerhard, Nijman, Sebastian M B

Volltext

Synthetic Lethal Vulnerabilities of Cancer von Fece de la Cruz, Ferran, Gapp, Bianca V, Nijman, Sebastian M.B

Volltext

Quality of life several years after myocardial infarction: comparing the MONICA/KORA registry to the general population von Schweikert, Bernd, Hunger, Matthias, Meisinger, Christa, König, Hans-Helmut, Gapp, Oliver, Holle, Rolf

Volltext

Early life stress in fathers improves behavioural flexibility in their offspring von Gapp, Katharina, Soldado-Magraner, Saray, Alvarez-Sánchez, María, Bohacek, Johannes, Vernaz, Gregoire, Shu, Huan, Franklin, Tamara B., Wolfer, David, Mansuy, Isabelle M.

Volltext

Parallel reverse genetic screening in mutant human cells using transcriptomics von Gapp, Bianca V, Konopka, Tomasz, Penz, Thomas, Dalal, Vineet, Bürckstümmer, Tilmann, Bock, Christoph, Nijman, Sebastian MB

Volltext

Identification and Characterization of Novel Variations in Platelet G-Protein Coupled Receptor (GPCR) Genes in Patients Historically Diagnosed with Type 1 von Willebrand Disease von Stockley, Jacqueline, Nisar, Shaista P, Leo, Vincenzo C, Sabi, Essa, Cunningham, Margaret R, Eikenboom, Jeroen C, Lethagen, Stefan, Schneppenheim, Reinhard, Goodeve, Anne C, Watson, Steve P, Mundell, Stuart J, Daly, Martina E

Volltext

UTS2B Defines a Novel Enteroendocrine Cell Population and Regulates GLP-1 Secretion Through SSTR5 in Male Mice von Tang, Cong, Ksiazek, Iwona, Siccardi, Noemie, Gapp, Berangere, Weber, Delphine, Wirsching, Johann, Beck, Valerie, Reist, Matthias, Gaudet, Laurent, Stuber, Nathalie, Surber, Sabrina Silvia, Mao, Xiaohong, Nicholson, Thomas B, Carbone, Walter, Beibel, Martin, Roma, Guglielmo, Gubser Keller, Caroline, Bassilana, Frederic

Volltext

A Close Eye on the Eagle-Eyed Visual Acuity Hypothesis of Autism von Bölte, Sven, Schlitt, Sabine, Gapp, Volker, Hainz, Daniela, Schirman, Shella, Poustka, Fritz, Weber, Bernhard, Freitag, Christine, Ciaramidaro, Angela, Walter, Henrik

Volltext