The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells von Marçais, Antoine, Cherfils-Vicini, Julien, Viant, Charlotte, Degouve, Sophie, Viel, Sébastien, Fenis, Aurore, Rabilloud, Jessica, Mayol, Katia, Tavares, Armelle, Bienvenu, Jacques, Gangloff, Yann-Gaël, Gilson, Eric, Vivier, Eric, Walzer, Thierry

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Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation von Osseni, Alexis, Ravel-Chapuis, Aymeric, Belotti, Edwige, Scionti, Isabella, Gangloff, Yann-Gaël, Moncollin, Vincent, Mazelin, Laetitia, Mounier, Remi, Leblanc, Pascal, Jasmin, Bernard J., Schaeffer, Laurent

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H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles von Belotti, Edwige, Lacoste, Nicolas, Simonet, Thomas, Papin, Christophe, Padmanabhan, Kiran, Scionti, Isabella, Gangloff, Yann-Gaël, Ramos, Lorrie, Dalkara, Defne, Hamiche, Ali, Dimitrov, Stefan, Schaeffer, Laurent

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Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle von Song, Zhe, Moore, Daniel R., Hodson, Nathan, Ward, Carl, Dent, Jessica R., O’Leary, Mary F., Shaw, Andrew M., Hamilton, D. Lee, Sarkar, Sovan, Gangloff, Yann-Gaël, Hornberger, Troy A., Spriet, Lawrence L., Heigenhauser, George J., Philp, Andrew

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Increased Serpina3n release into circulation during glucocorticoid‐mediated muscle atrophy von Gueugneau, Marine, d'Hose, Donatienne, Barbé, Caroline, Barsy, Marie, Lause, Pascale, Maiter, Dominique, Bindels, Laure B., Delzenne, Nathalie M., Schaeffer, Laurent, Gangloff, Yann‐Gaël, Chambon, Christophe, Coudy‐Gandilhon, Cécile, Béchet, Daniel, Thissen, Jean‐Paul

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Arrest of myelination and reduced axon growth when Schwann cells lack mTOR von Sherman, Diane L, Krols, Michiel, Wu, Lai-Man N, Grove, Matthew, Nave, Klaus-Armin, Gangloff, Yann-Gaël, Brophy, Peter J

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H syndrome mimicking Erdheim Chester disease: new entity and therapeutic perspectives von Lequain, Hippolyte, Gerfaud-Valentin, Mathieu, Emile, Jean-François, Gangloff, Yann-Gaël, Boursier, Guilaine, Deligny, Christophe, Le Guenno, Guillaume, Tantot, Juliet, Valantin, Julie, Savey, Lea, Bachmeyer, Claude, Jamilloux, Yvan, Schaeffer, Laurent, Leblanc, Pascal, Sève, Pascal

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Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole‐body homeostasis von Zhang, Qing, Duplany, Agnès, Moncollin, Vincent, Mouradian, Sandrine, Goillot, Evelyne, Mazelin, Laetitia, Gauthier, Karine, Streichenberger, Nathalie, Angleraux, Céline, Chen, Jie, Ding, Shuzhe, Schaeffer, Laurent, Gangloff, Yann‐Gaël

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Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy von Risson, Valérie, Mazelin, Laetitia, Roceri, Mila, Sanchez, Hervé, Moncollin, Vincent, Corneloup, Claudine, Richard-Bulteau, Hélène, Vignaud, Alban, Baas, Dominique, Defour, Aurélia, Freyssenet, Damien, Tanti, Jean-François, Le-Marchand-Brustel, Yannick, Ferrier, Bernard, Conjard-Duplany, Agnès, Romanino, Klaas, Bauché, Stéphanie, Hantaï, Daniel, Mueller, Matthias, Kozma, Sara C, Thomas, George, Rüegg, Markus A, Ferry, Arnaud, Pende, Mario, Bigard, Xavier, Koulmann, Nathalie, Schaeffer, Laurent, Gangloff, Yann-Gaël

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mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis von Mazelin, Laetitia, Panthu, Baptiste, Nicot, Anne-Sophie, Belotti, Edwige, Tintignac, Lionel, Teixeira, Geoffrey, Zhang, Qing, Risson, Valérie, Baas, Dominique, Delaune, Emilie, Derumeaux, Geneviève, Taillandier, Daniel, Ohlmann, Theophile, Ovize, Michel, Gangloff, Yann-Gaël, Schaeffer, Laurent

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Disruption of the Mouse mTOR Gene Leads to Early Postimplantation Lethality and Prohibits Embryonic Stem Cell Development von Gangloff, Yann-Gaël, Mueller, Matthias, Dann, Stephen G., Svoboda, Petr, Sticker, Melanie, Spetz, Jean-Francois, Um, Sung Hee, Brown, Eric J., Cereghini, Silvia, Thomas, George, Kozma, Sara C.

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Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function von Romanino, Klaas, Mazelin, Laetitia, Albert, Verena, Conjard-Duplany, Agnès, Lin, Shuo, Bentzinger, C. Florian, Handschin, Christoph, Puigserver, Pere, Zorzato, Francesco, Schaeffer, Laurent, Gangloff, Yann-Gaël, Rüegg, Markus A

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Crystal Structure of a Subcomplex of Human Transcription Factor TFIID Formed by TATA Binding Protein-associated Factors hTAF4 (hTAFII135) and hTAF12 (hTAFII20) von Werten, Sebastiaan, Mitschler, André, Romier, Christophe, Gangloff, Yann-Gaël, Thuault, Sylvie, Davidson, Irwin, Moras, Dino

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Histone Folds Mediate Selective Heterodimerization of Yeast TAFII25 with TFIID Components yTAFII47 and yTAFII65 and with SAGA Component ySPT7 von Gangloff, Yann-Gaël, Sanders, Steven L., Romier, Christophe, Kirschner, Doris, Weil, P. Anthony, Tora, Laszlo, Davidson, Irwin

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S6K1 controls pancreatic β cell size independently of intrauterine growth restriction von Um, Sung Hee, Sticker-Jantscheff, Melanie, Chau, Gia Cac, Vintersten, Kristina, Mueller, Matthias, Gangloff, Yann-Gael, Adams, Ralf H, Spetz, Jean-Francois, Elghazi, Lynda, Pfluger, Paul T, Pende, Mario, Bernal-Mizrachi, Ernesto, Tauler, Albert, Tschöp, Matthias H, Thomas, George, Kozma, Sara C

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Distinct Mutations in Yeast TAFII25 Differentially Affect the Composition of TFIID and SAGA Complexes as Well as Global Gene Expression Patterns von Kirschner, Doris B., vom Baur, Elmar, Thibault, Christelle, Sanders, Steven L., Gangloff, Yann-Gaël, Davidson, Irwin, Weil, P. Anthony, Tora, Làszlò

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Functional Analysis of the TFIID-specific Yeast TAF4 (yTAFII48) Reveals an Unexpected Organization of Its Histone-fold Domain von Thuault, Sylvie, Gangloff, Yann-Gaël, Kirchner, Jay, Sanders, Steven, Werten, Sebastiaan, Romier, Christophe, Weil, P. Anthony, Davidson, Irwin

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The histone fold is a key structural motif of transcription factor TFIID von Gangloff, Yann-Gaël, Romier, Christophe, Thuault, Sylvie, Werten, Sebastiaan, Davidson, Irwin

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Dissecting the interaction network of multiprotein complexes by pairwise coexpression of subunits in E. coli von Fribourg, Sébastien, Romier, Christophe, Werten, Sebastiaan, Gangloff, Yann-Gaël, Poterszman, Arnaud, Moras, Dino

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The ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways von Coudert, L., Osseni, A., Gangloff, Yann-Gaël, Schaeffer, L., Leblanc, P.

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