Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 3Development of a Scalable Enzymatic Oxidation Process von Kim, Jungchul, Zhang, Victoria, Abe, Kotoe, Qin, Yangzhong, DiRocco, Daniel A., McMullen, Jonathan P., Sun, Alexandra, Gangam, Rekha, Chow, Matthew, Pitts-McCoy, Anthony, Malkani, Arnav Sunil

Volltext

Novel Analytical Approach to Quantify Reactive Potentially Mutagenic Sulfonate Ester Impurities in Pharmaceutical Compounds and Its Application in the Development of a Control Stra... von Gangam, Rekha, Liu, Wenjun, Pirnot, Michael T., Dalby, Stephen M., Fine, Adam J., Kassim, Brittany

Volltext

Real-Time Monitoring of In Situ Gas-Phase H/D Exchange Reactions of Cations by Atmospheric Pressure Helium Plasma Ionization Mass Spectrometry (HePI-MS) von Attygalle, Athula B, Gangam, Rekha, Pavlov, Julius

Volltext

Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 1Process History and Development Strategy von DiRocco, Daniel A., Zhong, Yong-Li, Le, Diane N., McCann, Scott D., Hethcox, J. Caleb, Kim, Jungchul, Kolev, Joshua N., Kosjek, Birgit, Dalby, Stephen M., McMullen, Jonathan P., Gangam, Rekha, Morris, William J.

Volltext

Manufacturing Process Development for Belzutifan, Part 4: Nitrogen Flow Criticality for Transfer Hydrogenation Control von Salehi Marzijarani, Nastaran, Fine, Adam J, Dalby, Stephen M, Gangam, Rekha, Poudyal, Samiksha, Behre, Taylor, Ekkati, Anil R, Armstrong, Brittany M, Shultz, C. Scott, Dance, Zachary E. X, Stone, Kevin

Volltext

Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan von Cheung‐Lee, Wai Ling, Kolev, Joshua N., McIntosh, John A., Gil, Agnieszka A., Pan, Weilan, Xiao, Li, Velásquez, Juan E., Gangam, Rekha, Winston, Matthew S., Li, Shasha, Abe, Kotoe, Alwedi, Embarek, Dance, Zachary E. X., Fan, Haiyang, Hiraga, Kaori, Kim, Jungchul, Kosjek, Birgit, Le, Diane N., Marzijarani, Nastaran Salehi, Mattern, Keith, McMullen, Jonathan P., Narsimhan, Karthik, Vikram, Ajit, Wang, Wei, Yan, Jia‐Xuan, Yang, Rong‐Sheng, Zhang, Victoria, Zhong, Wendy, DiRocco, Daniel A., Morris, William J., Murphy, Grant S., Maloney, Kevin M.

Volltext

Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 4Applications of Process Analytical Technology in Heterogeneous Biocatalytic Hydroxylation von Qin, Yangzhong, Mattern, Keith A., Zhang, Victoria, Abe, Kotoe, Kim, Jungchul, Zheng, Michelle, Gangam, Rekha, Kalinin, Alexei, Kolev, Joshua N., Axnanda, Stephanus, Dance, Zachary E. X., Ayesa, Umme, Ji, Yining, Grosser, Shane T., Appiah-Amponsah, Emmanuel, McMullen, Jonathan P.

Volltext

Regulated In Situ Generation of Molecular Ions or Protonated Molecules under Atmospheric-Pressure Helium-Plasma-Ionization Mass Spectrometric Conditions von Gangam, Rekha, Pavlov, Julius, Attygalle, Athula B.

Volltext

An Investigation into the Unexpected Corrosion of Nickel Alloy Vessels with Selectfluor von Wang, Tao, Vickery, Thomas P, Bachert, Donald, Gangam, Rekha, Margelefsky, Eric, Phillips, Eric M, Dalby, Stephen M, Liu, Wenjun, Peterman, Amanda, Zawatzky, Kerstin, Cohen, Ryan D

Volltext

Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan von Cheung‐Lee, Wai Ling, Kolev, Joshua N., McIntosh, John A., Gil, Agnieszka A., Pan, Weilan, Xiao, Li, Velásquez, Juan E., Gangam, Rekha, Winston, Matthew S., Li, Shasha, Abe, Kotoe, Alwedi, Embarek, Dance, Zachary E. X., Fan, Haiyang, Hiraga, Kaori, Kim, Jungchul, Kosjek, Birgit, Le, Diane N., Marzijarani, Nastaran Salehi, Mattern, Keith, McMullen, Jonathan P., Narsimhan, Karthik, Vikram, Ajit, Wang, Wei, Yan, Jia‐Xuan, Yang, Rong‐Sheng, Zhang, Victoria, Zhong, Wendy, DiRocco, Daniel A., Morris, William J., Murphy, Grant S., Maloney, Kevin M.

Volltext