Intrinsic versus idiosyncratic drug-induced hepatotoxicity--two villains or one? von Roth, Robert A, Ganey, Patricia E

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Idiosyncratic Drug-Induced Liver Injury: Is Drug-Cytokine Interaction the Linchpin? von Roth, Robert A, Maiuri, Ashley R, Ganey, Patricia E

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Idiosyncratic Drug-Induced Liver Injury and the Role of Inflammatory Stress with an Emphasis on an Animal Model of Trovafloxacin Hepatotoxicity von Shaw, Patrick J., Ganey, Patricia E., Roth, Robert A.

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Inflammatory Stress and Idiosyncratic Hepatotoxicity: Hints from Animal Models von Deng, Xiaomin, Luyendyk, James P, Ganey, Patricia E, Roth, Robert A

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Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice von Miyakawa, Kazuhisa, Joshi, Nikita, Sullivan, Bradley P., Albee, Ryan, Brandenberger, Christina, Jaeschke, Hartmut, McGill, Mitchell R., Scott, Michael A., Ganey, Patricia E., Luyendyk, James P., Roth, Robert A.

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Role of the Kupffer Cell in Mediating Hepatic Toxicity and Carcinogenesis von Roberts, Ruth A., Ganey, Patricia E., Ju, Cynthia, Kamendulis, Lisa M., Rusyn, Ivan, Klaunig, James E.

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Commending Exceptional Society of Toxicology Leadership During Extraordinary Times von Cook, Jon C, Burns Naas, Leigh Ann, Ganey, Patricia E

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Fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, blocks steatosis and alters the inflammatory response in a mouse model of inflammation-dioxin interaction von Olivero-Verbel, Jesus, Harkema, Jack R., Roth, Robert A., Ganey, Patricia E.

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Complement activation in acetaminophen-induced liver injury in mice von Singhal, Rohit, Ganey, Patricia E, Roth, Robert A

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Lipopolysaccharide and Trovafloxacin Coexposure in Mice Causes Idiosyncrasy-Like Liver Injury Dependent on Tumor Necrosis Factor-Alpha von Shaw, Patrick J., Hopfensperger, Marie J., Ganey, Patricia E., Roth, Robert A.

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Amiodarone Exposure During Modest Inflammation Induces Idiosyncrasy-like Liver Injury in Rats: Role of Tumor Necrosis Factor-alpha von Lu, Jingtao, Jones, A. Daniel, Harkema, Jack R., Roth, Robert A., Ganey, Patricia E.

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Molecular mechanisms of hepatocellular apoptosis induced by trovafloxacin-tumor necrosis factor-alpha interaction von Beggs, Kevin M, Fullerton, Aaron M, Miyakawa, Kazuhisa, Ganey, Patricia E, Roth, Robert A

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Role of the coagulation system in acetaminophen‐induced hepatotoxicity in mice von Ganey, Patricia E., Luyendyk, James P., Newport, Sandra W., Eagle, Theresa M., Maddox, Jane F., Mackman, Nigel, Roth, Robert A.

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Trovafloxacin enhances lipopolysaccharide-stimulated production of tumor necrosis factor-α by macrophages: role of the DNA damage response von Poulsen, Kyle L, Olivero-Verbel, Jesus, Beggs, Kevin M, Ganey, Patricia E, Roth, Robert A

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Beyond Metabolism: Role of the Immune System in Hepatic Toxicity von Hastings, Kenneth L., Green, Martin D., Gao, Bin, Ganey, Patricia E., Roth, Robert A., Burleson, Gary R.

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Cytotoxic Synergy Between Cytokines and NSAIDs Associated With Idiosyncratic Hepatotoxicity Is Driven by Mitogen-Activated Protein Kinases von Maiuri, Ashley R, Breier, Anna B, Gora, Lukas F J, Parkins, Robert V, Ganey, Patricia E, Roth, Robert A

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Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia tel... von Beggs, Kevin M, Maiuri, Ashley R, Fullerton, Aaron M, Poulsen, Kyle L, Breier, Anna B, Ganey, Patricia E, Roth, Robert A

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The Role of Tumor Necrosis Factor Alpha in Lipopolysaccharide/Ranitidine-Induced Inflammatory Liver Injury von Tukov, Francis F., Luyendyk, James P., Ganey, Patricia E., Roth, Robert A.

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Synergistic Cytotoxicity from Drugs and Cytokines In Vitro as an Approach to Classify Drugs According to Their Potential to Cause Idiosyncratic Hepatotoxicity: A Proof-of-Concept S... von Maiuri, Ashley R, Wassink, Bronlyn, Turkus, Jonathan D, Breier, Anna B, Lansdell, Theresa, Kaur, Gurpreet, Hession, Sarah L, Ganey, Patricia E, Roth, Robert A

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Tumor necrosis factor-alpha potentiates the cytotoxicity of amiodarone in Hepa1c1c7 cells: roles of caspase activation and oxidative stress von Lu, Jingtao, Miyakawa, Kazuhisa, Roth, Robert A, Ganey, Patricia E

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