Nutrient Deprivation Elicits a Transcriptional and Translational Inflammatory Response Coupled to Decreased Protein Synthesis von Gameiro, Paulo A., Struhl, Kevin

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In Vivo HIF-Mediated Reductive Carboxylation Is Regulated by Citrate Levels and Sensitizes VHL-Deficient Cells to Glutamine Deprivation von Gameiro, Paulo A., Yang, Juanjuan, Metelo, Ana M., Pérez-Carro, Rocio, Baker, Rania, Wang, Zongwei, Arreola, Alexandra, Rathmell, W. Kimryn, Olumi, Aria, López-Larrubia, Pilar, Stephanopoulos, Gregory, Iliopoulos, Othon

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Cytotoxic T-cells mediate exercise-induced reductions in tumor growth von Rundqvist, Helene, Veliça, Pedro, Barbieri, Laura, Gameiro, Paulo A, Bargiela, David, Gojkovic, Milos, Mijwel, Sara, Reitzner, Stefan Markus, Wulliman, David, Ahlstedt, Emil, Ule, Jernej, Östman, Arne, Johnson, Randall S

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Oncogenic K‐Ras decouples glucose and glutamine metabolism to support cancer cell growth von Gaglio, Daniela, Metallo, Christian M, Gameiro, Paulo A, Hiller, Karsten, Danna, Lara Sala, Balestrieri, Chiara, Alberghina, Lilia, Stephanopoulos, Gregory, Chiaradonna, Ferdinando

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Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia von Metallo, Christian M., Gameiro, Paulo A., Bell, Eric L., Mattaini, Katherine R., Yang, Juanjuan, Hiller, Karsten, Jewell, Christopher M., Johnson, Zachary R., Irvine, Darrell J., Guarente, Leonard, Kelleher, Joanne K., Vander Heiden, Matthew G., Iliopoulos, Othon, Stephanopoulos, Gregory

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Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers von Okazaki, Arimichi, Gameiro, Paulo A, Christodoulou, Danos, Laviollette, Laura, Schneider, Meike, Chaves, Frances, Stemmer-Rachamimov, Anat, Yazinski, Stephanie A, Lee, Richard, Stephanopoulos, Gregory, Zou, Lee, Iliopoulos, Othon

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Metabolic turnover and dynamics of modified ribonucleosides by 13C labeling von Gameiro, Paulo A., Encheva, Vesela, Dos Santos, Mariana Silva, MacRae, James I., Ule, Jernej

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Cofactor Balance by Nicotinamide Nucleotide Transhydrogenase (NNT) Coordinates Reductive Carboxylation and Glucose Catabolism in the Tricarboxylic Acid (TCA) Cycle von Gameiro, Paulo A., Laviolette, Laura A., Kelleher, Joanne K., Iliopoulos, Othon, Stephanopoulos, Gregory

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Lactate exposure shapes the metabolic and transcriptomic profile of CD8+ T cells von Barbieri, Laura, Veliça, Pedro, Gameiro, Paulo A, Cunha, Pedro P, Foskolou, Iosifina P, Rullman, Eric, Bargiela, David, Johnson, Randall S, Rundqvist, Helene

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Loss of RBF1 changes glutamine catabolism von Nicolay, Brandon N, Gameiro, Paulo A, Tschöp, Katrin, Korenjak, Michael, Heilmann, Andreas M, Asara, John M, Stephanopoulos, Gregory, Iliopoulos, Othon, Dyson, Nicholas J

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Targeted profiling of RNA translation reveals mTOR-4EBP1/2-independent translation regulation of mRNAs encoding ribosomal proteins von Li, Ben B., Qian, Changli, Gameiro, Paulo A., Liu, Chin-Chih, Jiang, Tao, Roberts, Thomas M., Struhl, Kevin, Zhao, Jean J.

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Control scheme for hybridised electric vehicles with an online power follower management strategy von Trovão, João Pedro Fernandes, Pereirinha, Paulo José Gameiro

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13C Isotope-Assisted Methods for Quantifying Glutamine Metabolism in Cancer Cells von Zhang, Jie, Ahn, Woo Suk, Gameiro, Paulo A., Keibler, Mark A., Zhang, Zhe, Stephanopoulos, Gregory

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Abstract 1123: Glutaminase inhibitors suppress pyrimidine synthesis and promote DNA replication stress in VHL -deficient human renal cancer cells von Okazaki, Arimichi, Gameiro, Paulo, Stephanopoulos, Gregory, Iliopoulos, Othon

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Metabolic turnover and dynamics of modified ribonucleosides by 13 C labeling von Gameiro, Paulo A, Encheva, Vesela, Dos Santos, Mariana Silva, MacRae, James I, Ule, Jernej

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Glutaminase and poly polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers von Okazaki, Arimichi, Gameiro, Paulo A, Christodoulou, Danos, Laviollette, Laura, Schneider, Meike, Chaves, Frances, Stemmer-Rachamimov, Anat, Yazinski, Stephanie A, Lee, Richard, Stephanopoulos, Gregory, Zou, Lee, Iliopoulos, Othon

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Glutaminase and poly von Okazaki, Arimichi, Gameiro, Paulo A, Christodoulou, Danos, Laviollette, Laura, Schneider, Meike, Chaves, Frances, Stemmer-Rachamimov, Anat, Yazinski, Stephanie A, Lee, Richard, Stephanopoulos, Gregory, Zou, Lee, Iliopoulos, Othon

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Abstract 1132: Regulation of the glutamine-to-lipid pathway by HIF: Reductive TCA cycle is a metabolic signature of VHL deficiency von Yang, Juanjuan, Gameiro, Paulo A., Stephanopoulos, Gregory, Iliopoulos, Othon

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Abstract 1001: Reductive tricarboxylic acid metabolism of glutamine mediates lipogenesis under hypoxia von Metallo, Christian, Gameiro, Paulo, Heiden, Matthew Vander, Ilioupoulos, Othon, Stephanopoulos, Greg

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Abstract 1881: Hypoxia Inducible Factor (HIF) promotes reductive carboxylation by regulating citrate levels and renders VHL-deficient and hypoxic cells sensitive to glutamine depri... von Gameiro, Paulo, Metelo, Ana, Pérez-Carro, Rocio, Arreolla, Alexandra, Baker, Rania, Wang, Zongwei, Olumi, Aria, Rathmell, Kimryn, López-Larrubia, Pilar, Stephanopoulos, Gregory, Iliopoulos, Othon

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