Identification of ligand and receptor interactions in CKD and MASH through the integration of single cell and spatial transcriptomics von Moreno, Jaime, Gluud, Lise Lotte, Galsgaard, Elisabeth D, Hvid, Henning, Mazzoni, Gianluca, Das, Vivek

Volltext

Evaluation of Gremlin-1 as a therapeutic target in metabolic dysfunction-associated steatohepatitis von Horn, Paul, Norlin, Jenny, Almholt, Kasper, Viuff, Birgitte M, Galsgaard, Elisabeth D, Hald, Andreas, Zosel, Franziska, Demuth, Helle, Poulsen, Svend, Norby, Peder L, Rasch, Morten G, Vyberg, Mogens, Fleckner, Jan, Werge, Mikkel Parsberg, Gluud, Lise Lotte, Rink, Marco R, Shepherd, Emma, Northall, Ellie, Lalor, Patricia F, Weston, Chris J, Fog-Tonnesen, Morten, Newsome, Philip N

Volltext

Temporal Regulation of Glomerular and Cortical Tubulointerstitial Genes Involved in the Development of Nephrotoxic Serum Nephritis von Ougaard, Maria E., Sembach, Frederikke E., Kvist, Peter H., Tonnesen, Morten, Frederiksen, Klaus S., Egfjord, Martin, Jensen, Henrik E., Galsgaard, Elisabeth D.

Volltext

STAT5 Activity in Pancreatic β-Cells Influences the Severity of Diabetes in Animal Models of Type 1 and 2 Diabetes von JACKEROTT, Malene, MØLDRUP, Annette, THAMS, Peter, GALSGAARD, Elisabeth D, KNUDSEN, Jakob, LEE, Ying C, NIELSEN, Jens Høiriis

Volltext

Regulation of integrin α6A by lactogenic hormones in rat pancreatic β‐cells: Implications for the physiological adaptation to pregnancy von Møldrup, Annette, Lindberg, Martin Nerup, Galsgaard, Elisabeth D., Henriksen, Ulrik, Dalgaard, Louise T., Nielsen, Jens Høiriis

Volltext

Optimising streptozotocin dosing to minimise renal toxicity and impairment of stomach emptying in male 129/Sv mice von Nørgaard, Sisse A, Søndergaard, Henrik, Sørensen, Dorte B, Galsgaard, Elisabeth D, Hess, Constanze, Sand, Fredrik W

Volltext

STAT5 activation by human GH protects insulin-producing cells against interleukin-1β, interferon-γ and tumour necrosis factor-α-induced apoptosis independent of nitric oxide produc... von Jensen, Janne, Galsgaard, Elisabeth D, Karlsen, Allan E, Lee, Ying C, Nielsen, Jens H

Volltext

NASH-inducing Diets in Göttingen Minipigs von Pedersen, Henrik D., Galsgaard, Elisabeth D., Christoffersen, Berit Ø., Cirera, Susanna, Holst, Dorte, Fredholm, Merete, Latta, Markus

Volltext

Balance between activating NKG2D, DNAM‐1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblas... von Nielsen, Natasja, Pascal, Veronique, Fasth, Andreas E. R., Sundström, Yvonne, Galsgaard, Elisabeth D., Ahern, David, Andersen, Martin, Baslund, Bo, Bartels, Else M., Bliddal, Henning, Feldmann, Marc, Malmström, Vivianne, Berg, Louise, Spee, Pieter, Söderström, Kalle

Volltext

Lectin-like transcript 1 is a marker of germinal center-derived B-cell non-Hodgkin's lymphomas dampening natural killer cell functions von Germain, Claire, Guillaudeux, Thierry, Galsgaard, Elisabeth D, Hervouet, Catherine, Tekaya, Nedra, Gallouet, Anne-Sophie, Fassy, Julien, Bihl, Franck, Poupon, Gwenola, Lazzari, Anne, Spee, Pieter, Anjuère, Fabienne, Pangault, Céline, Tarte, Karin, Tas, Patrick, Xerri, Luc, Braud, Veronique M

Volltext

Regulation of β-cell mass by hormones and growth factors von NIELSEN, Jens Høiriis, GALSGAARD, Elisabeth D, MØLDRUP, Annette, FRIEDRICHSEN, Birgitte Nissen, BILLESTRUP, Nils, HANSEN, Johnny A, LEE, Ying C, CARLSSON, Carina

Volltext

Sensitive and Specific In Situ Hybridization for Early Drug Discovery von Usher, Pernille A., Galsgaard, Elisabeth D., Kruse, Kimberly, Wang, Jishu, Krogh, Berit O., Mandelbaum, Jette, Almholt, Kasper

Volltext

Intratumoral Interleukin-21 Increases Antitumor Immunity, Tumor-infiltrating CD8+ T-cell Density and Activity, and Enlarges Draining Lymph Nodes von SØNDERGAARD, Henrik, GALSGAARD, Elisabeth D, BARTHOLOMAEUSSEN, Monica, STRATEN, Thor, ODUM, Niels, SKAK, Kresten

Volltext

Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors von Søndergaard, Henrik, Frederiksen, Klaus S, Thygesen, Peter, Galsgaard, Elisabeth D, Skak, Kresten, Kristjansen, Paul E G, Odum, Niels, Kragh, Michael

Volltext

Suppressor of Cytokine Signaling 3 (SOCS-3) Protects β-Cells against Interleukin-1 β- and Interferon-γ-Mediated Toxicity von Karlsen, Allan E., Rønn, Sif G., Lindberg, Karen, Johannesen, Jesper, Galsgaard, Elisabeth D., Pociot, Flemming, Nielsen, Jens H., Mandrup-Poulsen, Thomas, Nerup, Jørn, Billestrup, Nils

Volltext

Identification and Synthesis of a Novel Selective Partial PPARδ Agonist with Full Efficacy on Lipid Metabolism In Vitro and In Vivo von Sauerberg, Per, Olsen, Grith S, Jeppesen, Lone, Mogensen, John P, Pettersson, Ingrid, Jeppesen, Claus B, Daugaard, Jens R, Galsgaard, Elisabeth D, Ynddal, Lars, Fleckner, Jan, Panajotova, Vladimira, Polivka, Zdenek, Pihera, Pavel, Havranek, Miroslav, Wulff, Erik M

Volltext

Evaluation of Gremlin-1 as a therapeutic target in metabolic dysfunction-associated steatohepatitis von Horn, Paul, Norlin, Jenny, Almholt, Kasper, Viuff, Birgitte M, Galsgaard, Elisabeth D, Hald, Andreas, Zosel, Franziska, Demuth, Helle, Poulsen, Svend, Norby, Peder L, Rasch, Morten G, Vyberg, Mogens, Fleckner, Jan, Werge, Mikkel Parsberg, Gluud, Lise Lotte, Rink, Marco R, Shepherd, Emma, Northall, Ellie, Lalor, Patricia F, Weston, Chris J, Fog-Tonnesen, Morten, Newsome, Philip N

Volltext

Identification of Tyrosine Residues in the Intracellular Domain of the Growth Hormone Receptor Required for Transcriptional Signaling and Stat5 Activation (∗) von Hansen, Lone H., Wang, Xinzhong, Kopchick, John J., Bouchelouche, Pierre, Nielsen, Jens H., Galsgaard, Elisabeth D., Billestrup, Nils

Volltext

A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity von Roehlen, Natascha, Saviano, Antonio, El Saghire, Houssein, Crouchet, Emilie, Nehme, Zeina, Del Zompo, Fabio, Juehling, Frank, Oudot, Marine A, Durand, Sarah C, Duong, Francois H.T, Cherradi, Sara, Motos, Victor Gonzalez, Almeida, Nuno, Ponsolles, Clara, Heydmann, Laura, Ostyn, Tessa, Lallement, Antonin, Pessaux, Patrick, Felli, Emanuele, Cavalli, Andrea, Sgrignani, Jacopo, Thumann, Christine, Koutsopoulos, Olga, Fuchs, Bryan C, Hoshida, Yujin, Hofmann, Maike, Vyberg, Mogens, Viuff, Birgitte Martine, Galsgaard, Elisabeth D, Elson, Greg, Toso, Alberto, Meyer, Markus, Iacone, Roberto, Schweighoffer, Tamas, Teixeira, Geoffrey, Moll, Solange, De Vito, Claudio, Roskams, Tania, Davidson, Irwin, Heide, Danijela, Heikenwaelder, Mathias, Zeisel, Mirjam B, Lupberger, Joachim, Mailly, Laurent, Schuster, Catherine, Baumert, Thomas F

Volltext

Identification of Phenylalanine 346 in the Rat Growth Hormone Receptor as Being Critical for Ligand-mediated Internalization and Down-regulation (∗) von Allevato, Giovanna, Billestrup, Nils, Goujon, Laure, Galsgaard, Elisabeth D., Norstedt, Gunnar, Postel-Vinay, Marie-Catherine, Kelly, Paul A., Nielsen, Jens H.

Volltext