Discovery of Tertiary Sulfonamides as Potent Liver X Receptor Antagonists von Zuercher, William J, Buckholz, Richard G, Campobasso, Nino, Collins, Jon L, Galardi, Cristin M, Gampe, Robert T, Hyatt, Stephen M, Merrihew, Susan L, Moore, John T, Oplinger, Jeffrey A, Reid, Paul R, Spearing, Paul K, Stanley, Thomas B, Stewart, Eugene L, Willson, Timothy M

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Identification of a Nonsteroidal Liver X Receptor Agonist through Parallel Array Synthesis of Tertiary Amines von Collins, Jon L, Fivush, Adam M, Watson, Michael A, Galardi, Cristin M, Lewis, Michael C, Moore, Linda B, Parks, Derek J, Wilson, Joan G, Tippin, Tim K, Binz, Jane G, Plunket, Kelli D, Morgan, Daniel G, Beaudet, Elizabeth J, Whitney, Karl D, Kliewer, Steven A, Willson, Timothy M

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Identification of Liver Receptor Homolog-1 as a Novel Regulator of Apolipoprotein AI Gene Transcription von Delerive, Philippe, Galardi, Cristin M, Bisi, John E, Nicodeme, Edwige, Goodwin, Bryan

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Discovery of a novel and potent class of anti-HIV-1 maturation inhibitors with improved virology profile against gag polymorphisms von Tang, Jun, Jones, Stacey A., Jeffrey, Jerry L., Miranda, Sonia R., Galardi, Cristin M., Irlbeck, David M., Brown, Kevin W., McDanal, Charlene B., Johns, Brian A.

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Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPAR α von Xu, H. Eric, Stanley, Thomas B, Montana, Valerie G, Lambert, Millard H, Shearer, Barry G, Cobb, Jeffery E, McKee, David D, Galardi, Cristin M, Plunket, Kelli D, Nolte, Robert T, Parks, Derek J, Moore, John T, Kliewer, Steven A, Willson, Timothy M, Stimmel, Julie B

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Subtype Specific Effects of Peroxisome Proliferator-Activated Receptor Ligands on Corepressor Affinity von Stanley, Thomas B, Leesnitzer, Lisa M, Montana, Valerie G, Galardi, Cristin M, Lambert, Millard H, Holt, Jason A, Xu, H. Eric, Moore, Linda B, Blanchard, Steven G, Stimmel, Julie B

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Synthesis and Biological Evaluation of Macrocyclized Betulin Derivatives as a Novel Class of Anti-HIV-1 Maturation Inhibitors von Tang, Jun, Jones, Stacey A, Jeffery, Jerry L, Miranda, Sonia R, Galardi, Cristin M, Irlbeck, David M, Brown, Kevin W, McDanal, Charlene B, Han, Nianhe, Gao, Daxin, Wu, Yongyong, Shen, Bin, Liu, Chunyu, Xi, Caiming, Yang, Heping, Li, Rui, Yu, Yajun, Sun, Yufei, Jin, Zhimin, Wang, Erjuan, Johns, Brian A

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Pharmacophore Analysis of the Nuclear Oxysterol Receptor LXRα von Spencer, Thomas A, Li, Dansu, Russel, Jonathon S, Collins, Jon L, Bledsoe, Randy K, Consler, Thomas G, Moore, Linda B, Galardi, Cristin M, McKee, David D, Moore, John T, Watson, Michael A, Parks, Derek J, Lambert, Millard H, Willson, Timothy M

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Subtype Specific Effects of Peroxisome Proliferator-Activated Receptor Ligands on Corepressor Affinity von Stanley, Thomas B, Leesnitzer, Lisa M, Montana, Valerie G, Galardi, Cristin M, Lambert, Millard H, Holt, Jason A, Xu, H. Eric, Moore, Linda B, Blanchard, Steven G, Stimmel, Julie B

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Liver X Receptor (LXR) Regulation of the LXRα Gene in Human Macrophages von Whitney, Karl D., Watson, Michael A., Goodwin, Bryan, Galardi, Cristin M., Maglich, Jodi M., Wilson, Joan G., Willson, Timothy M., Collins, Jon L., Kliewer, Steven A.

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Liver X Receptor (LXR) Regulation of the LXRα Gene in Human Macrophages von Karl D. Whitney, Michael A. Watson, Bryan Goodwin, Cristin M. Galardi, Jodi M. Maglich, Joan G. Wilson, Timothy M. Willson, Jon L. Collins, Steven A. Kliewer

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Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha von Xu, H Eric, Stanley, Thomas B, Montana, Valerie G, Lambert, Millard H, Shearer, Barry G, Cobb, Jeffery E, McKee, David D, Galardi, Cristin M, Plunket, Kelli D, Nolte, Robert T, Parks, Derek J, Moore, John T, Kliewer, Steven A, Willson, Timothy M, Stimmel, Julie B

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CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption von Harper, Justin, Gordon, Shari, Chan, Chi Ngai, Wang, Hong, Lindemuth, Emily, Galardi, Cristin, Falcinelli, Shane D., Raines, Samuel L. M., Read, Jenna L., Nguyen, Kevin, McGary, Colleen S, Nekorchuk, Michael, Busman-Sahay, Kathleen, Schawalder, James, King, Colin, Pino, Maria, Micci, Luca, Cervasi, Barbara, Jean, Sherrie, Sanderson, Andrew, Johns, Brian, Koblansky, A. Alicia, Amrine-Madsen, Heather, Lifson, Jeffrey, Margolis, David M., Silvestri, Guido, Bar, Katharine J., Favre, David, Estes, Jacob D., Paiardini, Mirko

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Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo von Nixon, Christopher C., Mavigner, Maud, Sampey, Gavin C., Brooks, Alyssa D., Spagnuolo, Rae Ann, Irlbeck, David M., Mattingly, Cameron, Ho, Phong T., Schoof, Nils, Cammon, Corinne G., Tharp, Greg K., Kanke, Matthew, Wang, Zhang, Cleary, Rachel A., Upadhyay, Amit A., De, Chandrav, Wills, Saintedym R., Falcinelli, Shane D., Galardi, Cristin, Walum, Hasse, Schramm, Nathaniel J., Deutsch, Jennifer, Lifson, Jeffrey D., Fennessey, Christine M., Keele, Brandon F., Jean, Sherrie, Maguire, Sean, Liao, Baolin, Browne, Edward P., Ferris, Robert G., Brehm, Jessica H., Favre, David, Vanderford, Thomas H., Bosinger, Steven E., Jones, Corbin D., Routy, Jean-Pierre, Archin, Nancie M., Margolis, David M., Wahl, Angela, Dunham, Richard M., Silvestri, Guido, Chahroudi, Ann, Garcia, J. Victor

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A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis von Goodwin, Bryan, Jones, Stacey A., Price, Roger R., Watson, Michael A., McKee, David D., Moore, Linda B., Galardi, Cristin, Wilson, Joan G., Lewis, Michael C., Roth, Matthew E., Maloney, Patrick R., Willson, Timothy M., Kliewer, Steven A.

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Orphan Nuclear Receptor LRH-1 Is Required To Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development von Gu, Peili, Goodwin, Bryan, Chung, Arthur C.-K., Xu, Xueping, Wheeler, David A., Price, Roger R., Galardi, Cristin, Peng, Li, Latour, Anne M., Koller, Beverly H., Gossen, Jan, Kliewer, Steven A., Cooney, Austin J.

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CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after ART interruption von Harper, Justin, Gordon, Shari, Chan, Chi Ngai, Wang, Hong, Lindemuth, Emily, Galardi, Cristin, Falcinelli, Shane D., Raines, Samuel L.M., Read, Jenna L., Nguyen, Kevin, McGary, Colleen S, Nekorchuk, Michael, Busman-Sahay, Kathleen, Schawalder, James, King, Colin, Pino, Maria, Micci, Luca, Cervasi, Barbara, Jean, Sherrie, Sanderson, Andrew, Johns, Brian, Koblansky, A. Alicia, Amrine-Madsen, Heather, Lifson, Jeffrey, Margolis, David M., Silvestri, Guido, Bar, Katharine J, Favre, David, Estes, Jacob D., Paiardini, Mirko

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The relative activity of "function sparing" HIV-1 entry inhibitors on viral entry and CCR5 internalization: is allosteric functional selectivity a valuable therapeutic property? von Muniz-Medina, Vanessa M, Jones, Stacey, Maglich, Jodi M, Galardi, Cristin, Hollingsworth, Robert E, Kazmierski, Wieslaw M, Ferris, Robert G, Edelstein, Mark P, Chiswell, Karen E, Kenakin, Terry P

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Liver X receptors are regulators of adipocyte gene expression but not differentiation: identification of apoD as a direct target von Hummasti, Sarah, Laffitte, Bryan A, Watson, Michael A, Galardi, Cristin, Chao, Lily C, Ramamurthy, Lakshman, Moore, John T, Tontonoz, Peter

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Structure-Guided Design of N-Phenyl Tertiary Amines as Transrepression-Selective Liver X Receptor Modulators with Anti-Inflammatory Activity von Chao, Esther Y, Caravella, Justin A, Watson, Mike A, Campobasso, Nino, Ghisletti, Serena, Billin, Andrew N, Galardi, Cristin, Wang, Ping, Laffitte, Bryan A, Iannone, Marie A, Goodwin, Bryan J, Nichols, Jason A, Parks, Derek J, Stewart, Eugene, Wiethe, Robert W, Williams, Shawn P, Smallwood, Angela, Pearce, Kenneth H, Glass, Christopher K, Willson, Timothy M, Zuercher, William J, Collins, Jon L

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