Mutation-specific signaling profiles and kinase inhibitor sensitivities of juvenile myelomonocytic leukemia revealed by induced pluripotent stem cells von Tasian, Sarah K., Casas, Jessica A., Posocco, David, Gandre-Babbe, Shilpa, Gagne, Alyssa L., Liang, Ge, Loh, Mignon L., Weiss, Mitchell J., French, Deborah L., Chou, Stella T.

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Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching von Dawicki-McKenna, Jennine M., Felix, Alex J., Waxman, Elisa A., Cheng, Congsheng, Amado, Defne A., Ranum, Paul T., Bogush, Alexey, Dungan, Lea V., Maguire, Jean Ann, Gagne, Alyssa L., Heller, Elizabeth A., French, Deborah L., Davidson, Beverly L., Prosser, Benjamin L.

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The use of pluripotent stem cells to generate diagnostic tools for transfusion medicine von An, Hyun Hyung, Gagne, Alyssa L., Maguire, Jean Ann, Pavani, Giulia, Abdulmalik, Osheiza, Gadue, Paul, French, Deborah L., Westhoff, Connie M., Chou, Stella T.

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The HtrA Protease from Streptococcus pneumoniae Digests Both Denatured Proteins and the Competence-stimulating Peptide von Cassone, Marco, Gagne, Alyssa L., Spruce, Lynn A., Seeholzer, Steven H., Sebert, Michael E.

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GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells von Tiyaboonchai, Amita, Cardenas-Diaz, Fabian L., Ying, Lei, Maguire, Jean Ann, Sim, Xiuli, Jobaliya, Chintan, Gagne, Alyssa L., Kishore, Siddharth, Stanescu, Diana E., Hughes, Nkecha, De Leon, Diva D., French, Deborah L., Gadue, Paul

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Generation of CHOPi012-A iPSC line from a patient with visceral myopathy-related chronic intestinal pseudo-obstruction von Hashmi, Sohaib K, Schneider, Sabine, Gagne, Alyssa L, Maguire, Jean Ann, Gadue, Paul, Heuckeroth, Robert O, French, Deborah L

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Generation of CHOPe003-A ESC line to study an ACTG2 variant affecting smooth muscle development and function von Hashmi, Sohaib K., Schneider, Sabine, Gagne, Alyssa L., Maguire, Jean Ann, Anderson, Sierra, Gadue, Paul, Heuckeroth, Robert O., French, Deborah L.

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KOLF2.1J iPSCs carry CNVs associated with neurodevelopmental disorders von Gracia-Diaz, Carolina, Perdomo, Jonathan E., Khan, Munir E., Roule, Thomas, Disanza, Brianna L., Cajka, Gregory G., Lei, Sunyimeng, Gagne, Alyssa L., Maguire, Jean Ann, Shalem, Ophir, Bhoj, Elizabeth J., Ahrens-Nicklas, Rebecca C., French, Deborah L., Goldberg, Ethan M., Wang, Kai, Glessner, Joseph T., Akizu, Naiara

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A novel iPSC model reveals selective vulnerability of neurons in multiple sulfatase deficiency von Pham, Vi, Sertori Finoti, Livia, Cassidy, Margaret M., Maguire, Jean Ann, Gagne, Alyssa L., Waxman, Elisa A., French, Deborah L., King, Kaitlyn, Zhou, Zitao, Gelb, Michael H., Wongkittichote, Parith, Hong, Xinying, Schlotawa, Lars, Davidson, Beverly L., Ahrens-Nicklas, Rebecca C.

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Generation of three induced pluripotent stem cell lines from individuals with Aicardi-Goutières syndrome caused by a c.3019G>A (p.G1007R) autosomal dominant pathogenic variant in A... von Garcia, Luis, Gonzalez, Carlos Dominguez, Gagne, Alyssa, McGuire, Jean Ann, French, Deborah, Takanohashi, Asako, Almad, Akshata, Vanderver, Adeline, Sase, Sunetra

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Derivation and investigation of the first human cell-based model of Beckwith-Wiedemann syndrome von Chang, Suhee, Hur, Stella K., Naveh, Natali S. Sobel, Thorvaldsen, Joanne L., French, Deborah L., Gagne, Alyssa L, Jobaliya, Chintan D., Anguera, Montserrat C., Bartolomei, Marisa S., Kalish, Jennifer M

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Generation of 2 isogenic clones from a patient with Trisomy 21 and a GATA1 mutation von Takasaki, Kaoru, Kumar, Sara S., Gagne, Alyssa, French, Deborah L., Chou, Stella T.

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Generation of a double insulin and somatostatin reporter line, SCSe001-A-3, for the advancement of stem cell-derived pancreatic islets von Leavens, Karla F., Liao, Chia-min, Gagne, Alyssa L., Kishore, Siddharth, Cardenas-Diaz, Fabian L., French, Deborah L., Gadue, Paul

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Generation of CHOPi-008-B, a euploid iPSC line from a patient with Trisomy 21 and a GATA1 mutation von Takasaki, Kaoru, Kumar, Sara S, Gagne, Alyssa, French, Deborah L, Chou, Stella T

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Competence in Streptococcus pneumoniae is a response to an increasing mutational burden von Gagne, Alyssa L, Stevens, Kathleen E, Cassone, Marco, Pujari, Amit, Abiola, Olufunke E, Chang, Diana J, Sebert, Michael E

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Generation of human control iPSC line CHOPi004-A from juvenile foreskin fibroblast cells von Mukherjee, Somdutta, Gagne, Alyssa L., Maguire, Jean Ann, Jobaliya, Chintan D., Mills, Jason A., Gadue, Paul, French, Deborah L.

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Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN... von Maguire, Jean Ann, Gagne, Alyssa L., Gonzalez-Alegre, Pedro, Davidson, Beverly L., Shakkottai, Vikram, Gadue, Paul, French, Deborah L.

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Generation of three induced Pluripotent Stem Cell lines from individuals with Hypomyelination with Atrophy of Basal Ganglia and Cerebellum caused by a c.745G>A (p.D249N) autosomal... von Almad, Akshata A, Garcia, Luis, Takanohashi, Asako, Gagne, Alyssa, Yang, Wenli, Ann McGuire, Jean, French, Deborah, Vanderver, Adeline

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Generation of a human Tropomyosin 1 knockout iPSC line von Wilken, Madison B., Maguire, Jean Ann, Dungan, Lea V., Gagne, Alyssa, Osorio-Quintero, Catherine, Waxman, Elisa A, Chou, Stella T., Gadue, Paul, French, Deborah L., Thom, Christopher S.

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Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency von Schlotawa, Lars, Tyka, Karolina, Kettwig, Matthias, Ahrens‐Nicklas, Rebecca C, Baud, Matthias, Berulava, Tea, Brunetti‐Pierri, Nicola, Gagne, Alyssa, Herbst, Zackary M, Maguire, Jean A, Monfregola, Jlenia, Pena, Tonatiuh, Radhakrishnan, Karthikeyan, Schröder, Sophie, Waxman, Elisa A, Ballabio, Andrea, Dierks, Thomas, Fischer, André, French, Deborah L, Gelb, Michael H, Gärtner, Jutta

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