Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung von Genschmer, Kristopher R., Russell, Derek W., Lal, Charitharth, Szul, Tomasz, Bratcher, Preston E., Noerager, Brett D., Abdul Roda, Mojtaba, Xu, Xin, Rezonzew, Gabriel, Viera, Liliana, Dobosh, Brian S., Margaroli, Camilla, Abdalla, Tarek H., King, Robert W., McNicholas, Carmel M., Wells, J. Michael, Dransfield, Mark T., Tirouvanziam, Rabindra, Gaggar, Amit, Blalock, J. Edwin

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Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury von Zhao, Jiping, Yu, Hao, Liu, Yudong, Gibson, Sara A, Yan, Zhaoqi, Xu, Xin, Gaggar, Amit, Li, Pui-Kai, Li, Chenglong, Wei, Shi, Benveniste, Etty N, Qin, Hongwei

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Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in the Lower Airways in COPD von Dransfield, Mark T., MD, Wilhelm, Andrew M., MD, Flanagan, Brian, MD, Courville, Clifford, MD, Tidwell, Sherry L., RRT, Raju, S. Vamsee, PhD, Gaggar, Amit, MD, PhD, Steele, Chad, PhD, Tang, Li Ping, DVM, Liu, Bo, MD, Rowe, Steven M., MD, MSPH

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COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation von Patton, Michael John, Orihuela, Carlos J, Harrod, Kevin S, Bhuiyan, Mohammad A N, Dominic, Paari, Kevil, Christopher G, Fort, Daniel, Liu, Vincent X, Farhat, Maha, Koff, Jonathan L, Lal, Charitharth V, Gaggar, Anuj, Richter, Robert P, Erdmann, Nathaniel, Might, Matthew, Gaggar, Amit

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The closed eye harbours a unique microbiome in dry eye disease von Willis, Kent A., Postnikoff, Cameron K., Freeman, Amelia, Rezonzew, Gabriel, Nichols, Kelly, Gaggar, Amit, Lal, Charitharth V.

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Fibroblast growth factor 23 and Klotho contribute to airway inflammation von Krick, Stefanie, Grabner, Alexander, Baumlin, Nathalie, Yanucil, Christopher, Helton, Scott, Grosche, Astrid, Sailland, Juliette, Geraghty, Patrick, Viera, Liliana, Russell, Derek W, Wells, J Michael, Xu, Xin, Gaggar, Amit, Barnes, Jarrod, King, Gwendalyn D, Campos, Michael, Faul, Christian, Salathe, Matthias

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SARS-CoV-2 infection in cystic fibrosis: A multicentre prospective study with a control group, Italy, February-July 2020 von Colombo, Carla, Alicandro, Gianfranco, Dacco, Valeria, Gagliano, Vanessa, Morlacchi, Letizia Corinna, Casciaro, Rosaria, Pisi, Giovanna, Francalanci, Michela, Badolato, Raffaele, Bignamini, Elisabetta, Messore, Barbara, Lucanto, Maria Cristina, Leonetti, Giuseppina, Maschio, Massimo, Cipolli, Marco

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Airway microbiome composition correlates with lung function and arterial stiffness in an age-dependent manner von Lee, Shuen Yee, Mac Aogáin, Micheál, Fam, Kai Deng, Chia, Kar Ling, Binte Mohamed Ali, Nur A'tikah, Yap, Margaret M C, Yap, Eric P H, Chotirmall, Sanjay H, Lim, Chin Leong

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Alkalinity of neutrophil phagocytic vacuoles is modulated by HVCN1 and has consequences for myeloperoxidase activity von Levine, Adam P, Duchen, Michael R, de Villiers, Simon, Rich, Peter R, Segal, Anthony W

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Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase von Rada, Balázs, Jendrysik, Meghan A, Pang, Lan, Hayes, Craig P, Yoo, Dae-Goon, Park, Jonathan J, Moskowitz, Samuel M, Malech, Harry L, Leto, Thomas L

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NADPH oxidase limits innate immune responses in the lungs in mice von Segal, Brahm H, Han, Wei, Bushey, Jennifer J, Joo, Myungsoo, Bhatti, Zahida, Feminella, Joy, Dennis, Carly G, Vethanayagam, R Robert, Yull, Fiona E, Capitano, Maegan, Wallace, Paul K, Minderman, Hans, Christman, John W, Sporn, Michael B, Chan, Jefferson, Vinh, Donald C, Holland, Steven M, Romani, Luigina R, Gaffen, Sarah L, Freeman, Michael L, Blackwell, Timothy S

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A lactobacilli-based inhaled live biotherapeutic product attenuates pulmonary neutrophilic inflammation von Nicola, Teodora, Wenger, Nancy, Xu, Xin, Evans, Michael, Qiao, Luhua, Rezonzew, Gabriel, Yang, Youfeng, Jilling, Tamas, Margaroli, Camilla, Genschmer, Kristopher, Willis, Kent, Ambalavanan, Namasivayam, Blalock, J. Edwin, Gaggar, Amit, Lal, Charitharth Vivek

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A Critical Role for LTA₄H in Limiting Chronic Pulmonary Neutrophilic Inflammation von Snelgrove, Robert J., Jackson, Patricia L., Hardison, Matthew T., Noerager, Brett D., Kinloch, Andrew, Gaggar, Amit, Shastry, Suresh, Rowe, Steven M., Shim, Yun M., Hussell, Tracy, Blalock, J. Edwin

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Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure von Serban, Karina A, Petrusca, Daniela N, Mikosz, Andrew, Poirier, Christophe, Lockett, Angelia D, Saint, Lauren, Justice, Matthew J, Twigg, 3rd, Homer L, Campos, Michael A, Petrache, Irina

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Analysis of a large cohort of cystic fibrosis patients with severe liver disease indicates lung function decline does not significantly differ from that of the general cystic fibro... von Polineni, Deepika, Piccorelli, Annalisa V, Hannah, William B, Dalrymple, Sarah N, Pace, Rhonda G, Durie, Peter R, Ling, Simon C, Knowles, Michael R, Stonebraker, Jaclyn R

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Multi-dimensional flow cytometry analysis reveals increasing changes in the systemic neutrophil compartment during seven consecutive days of endurance exercise von van Staveren, Selma, Ten Haaf, Twan, Klöpping, Margot, Hilvering, Bart, Tinnevelt, Gerjen H, de Ruiter, Karin, Piacentini, Maria F, Roelands, Bart, Meeusen, Romain, de Koning, Jos J, Jansen, Jeroen J, Vrisekoop, Nienke, Koenderman, Leo

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Active transcription in the vascular bed characterizes rapid progression in idiopathic pulmonary fibrosis von Sharma, Nirmal S, Patel, Kapil, Sari, Ezgi, Shankar, Shruti, Gastanadui, Maria G, Moncada-Giraldo, Diego, Soto-Vazquez, Yixel, Stacks, Delores, Hecker, Louise, Dsouza, Kevin, Banday, Mudassir, O'Neill, Edward, Benson, Paul, Payne, Gregory, Margaroli, Camilla, Gaggar, Amit

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Immunomodulation in Cystic Fibrosis: Why and How? von Giacalone, Vincent D., Dobosh, Brian S., Gaggar, Amit, Tirouvanziam, Rabindra, Margaroli, Camilla

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A self-propagating matrix metalloprotease-9 (MMP-9) dependent cycle of chronic neutrophilic inflammation von Xu, Xin, Jackson, Patricia L, Tanner, Scott, Hardison, Matthew T, Abdul Roda, Mojtaba, Blalock, James Edwin, Gaggar, Amit

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Airway extracellular LTA4H concentrations are governed by release from liver hepatocytes and changes in lung vascular permeability von Mincham, Kyle T., Akthar, Samia, Patel, Dhiren F., Meyer, Garance F., Lloyd, Clare M., Gaggar, Amit, Blalock, James E., Snelgrove, Robert J.

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