Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib von Karkera, Jayaprakash D, Cardona, Gabriela Martinez, Bell, Katherine, Gaffney, Dana, Portale, Joseph C, Santiago-Walker, Ademi, Moy, Christopher H, King, Peter, Sharp, Michael, Bahleda, Rastislav, Luo, Feng R, Alvarez, John D, Lorenzi, Matthew V, Platero, Suso J

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Abstract 5027: Detection of soluble protein biomarkers in NSCLC serum samples by meso scale discovery electrochemiluminescence platform von Gaffney, Dana S., Bell, Katherine, Martinez, Gabriela, Karkera, Jayaprakash, Platero, Suso

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Abstract 950: In vivo efficacy and pharmacodynamic modulation of JNJ-64619178, a selective PRMT5 inhibitor, in human lung and hematologic preclinical models von Millar, Hillary J., Brehmer, Dirk, Verhulst, Tinne, Haddish-Berhane, Nahor, Greway, Tony, Gaffney, Dana, Boeckx, An, Heerde, Erika Van, Nys, Thomas, Portale, Joseph, Philippar, Ulrike, Wu, Tongfei, Laquerre, Sylvie, Packman, Kathryn

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Abstract 3905: Translational efficacy and safety modeling and simulation to support the clinical development of JNJ-64619178, a PRMT5 inhibitor von Guo, Yue, Haddish-Berhane, Nahor, Millar, Hillary J., Verhulst, Tinne, Greway, Tony, Zhou, Junguo, DeZwart, Loeckie, Gaffney, Dana, Portale, Joseph, Brehmer, Dirk, Boeckx, An, Heerde, Erika Van, Ouellet, Daniele

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Abstract 4325: The role of FGFR fusion genes as novel oncogenic targets von Martinez Cardona, Gabriela, Bell, Katherine, Gaffney, Dana, Portale, Joseph, Platero, Suso, Lorenzi, Matthew, Karkera, Jayaprakash

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Abstract 4326: Co-amplification of FGF receptors and ligands in FGFR inhibitor-sensitive cell lines von Bell, Katherine, Gaffney, Dana, Martinez-Cardona, Gabriela, Karkera, Jayaprakash, Platero, Suso

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Abstract 3990: FGFR3 mutations as novel oncogenic targets von Martinez Cardona, Gabriela, Gaffney, Dana, Bell, Katherine, Portale, Joseph, Dunworth, Matthew, Lorenzi, Matthew, Platero, Suso, Karkera, Jayaprakash

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Abstract 3174: A real-time qPCR approach to detect fusions between the KIF5B and RET genes in non-small cell lung cancer von Bell, Katherine, Gaffney, Dana, Martinez, Gabriela, Platero, Suso, Karkera, Jayaprakash

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Abstract 4859: JNJ-64619178, a selective and pseudo-irreversible PRMT5 inhibitor with potent in vitro and in vivo activity, demonstrated in several lung cancer models von Wu, Tongfei, Millar, Hillary, Gaffney, Dana, Beke, Lijs, Mannens, Geert, Vinken, Petra, Sommers, Ivan, Thuring, Jan-Willem, Sun, Weimei, Moy, Christopher, Pande, Vineet, Zhou, Junguo, Haddish-Berhane, Nahor, Salvati, Mark, Laquerre, Sylvie, Lorenzi, Matthew V., Brehmer, Dirk

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Abstract 1548: Genomic and molecular profiling of NSCLC formalin-fixed paraffin-embedded tumors von Gaffney, Dana S., Bell, Katherine, Martinez, Gabriela, Rajpurohit, Yashoda, Karkera, Jayaprakash, Moy, Christopher, Platero, Suso

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Abstract 4666: Profiling mesothelin protein expression by immunohistochemistry and gene expression in adenocarcinoma and squamous cell carcinoma of lung von Wong, Jackson, Gaffney, Dana, Sharp, Michael, Hertzog, Brenda, Karkera, Jayaprakash, Platero, Suso, Alvarez, John

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Anti-PD-1 antibody cetrelimab (JNJ-63723283) in patients with advanced cancers: Updated phase I/II study results von Rutkowski, Piotr, Felip, Enriqueta, Moreno, Victor, Trigo Perez, Jose Manuel, Calvo, Aitana, Kowalski, Dariusz, Cortinovis, Diego, Lee, James J., Manikhas, George, Plummer, Elizabeth Ruth, Maio, Michele, Ascierto, Paolo Antonio, Vladimirov, Vladimir Ivanovich, Gaffney, Dana, Li, Lilian Y., Bae, Kyounghwa, Greger, James G., Shin, Chu Ri, Xie, Hong, Calvo, Emiliano

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Abstract B03: Identification of R-spondin fusions in NSCLC von Karkera, Jayaprakash, Martinez, Gabriela, Bell, Katherine, Portale, Joseph, Gaffney, Dana, Lorenzi, Matthew V., Platero, Suso

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Abstract 2408: Identification of R-Spondin fusions in various types of human cancer von Cardona, Gabriela Martinez, Bell, Katherine, Portale, Joseph, Gaffney, Dana, Moy, Christopher, Platero, Suso, Lorenzi, Matthew V., Karkera, Jayaprakash

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Abstract 3467: Identification of androgen receptor splice variants, ESR1, CYP17, and CYP19 in human breast cancer von Martinez, Gabriela, Gaffney, Dana, Bell, Katherine, Platero, Suso, Ricci, Deborah, Li, Weimin, Karkera, Jayaprakash D.

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Abstract 5: Identification of androgen receptor (AR) splice variants, AR somatic mutations and TMPRSS2:ETS fusion genes in prostate cancer FFPET by qRT-PCR von Gaffney, Dana S., Martinez, Gabriela, Bell, Katherine, Platero, Suso, Ricci, Deborah, Karkera, Jayaprakash

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Abstract DDT02-04: A novel PRMT5 inhibitor with potent in vitro and in vivo activity in preclinical lung cancer models von Brehmer, Dirk, Wu, Tongfei, Mannens, Geert, Beke, Lijs, Vinken, Petra, Gaffney, Dana, Sun, Weimei, Pande, Vineet, Thuring, Jan-Willem, Millar, Hillary, Poggesi, Italo, Somers, Ivan, Boeckx, An, Parade, Marc, Heerde, Erika van, Nys, Thomas, Yanovich, Carol, Herkert, Barbara, Verhulst, Tinne, Jardin, Marc Du, Meerpoel, Lieven, Moy, Christopher, Diels, Gaston, Viellevoye, Marcel, Schepens, Wim, Poncelet, Alain, Linders, Joannes T., Lawson, Edward C., Edwards, James P., Chetty, Dushen, Laquerre, Sylvie, Lorenzi, Matthew V.

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Abstract 1443: Improved molecular characterization of circulating tumor cells von Rao, Chandra, Foulk, Brad, Nielsen, Karl, Vaidya, Bhavesh, Patel, Jaymala, Gaffney, Dana, Smirnov, Denis, Karkera, Jayaprakash, Connelly, Mark

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Abstract 1416: Aurora kinase is synthetic lethal with APC loss of function in engineered human colon organoid models von Gaffney, Dana S., Vesely, Eileen, Pocalyko, David, Bachman, Kurtis, Wiehagen, Karla, Cowley, Glenn, Wong, Victoria, Gokare, Prashanth, Guzzie-Peck, Peggy, Weiner, Sandy, De Smedt, Ann, Kinyamu-Akunda, Jacqueline, Bush, Tammy, Zhang, Zhuming, Schulingkamp, Robert, Boj, Sylvia F., Overmeer, Rene, Verissimo, Carla, Nair, Roshni

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Prespecified Candidate Biomarkers Identify Follicular Lymphoma Patients Who Achieved Longer Progression-Free Survival with Bortezomib―Rituximab Versus Rituximab von COIFFIER, Bertrand, WEIMIN LI, SCHAFFER, Michael E, OSMANOV, Evgenii A, XIAONAN HONG, SCHELIGA, Adriana, MAYER, Jiri, OFFNER, Fritz, RULE, Simon, TEIXEIRA, Adriana, ROMEJKO-JAROSINSKA, Joanna, DE VOS, Sven, HENITZ, Erin D, CRUMP, Michael, SHPILBERG, Ofer, ZINZANI, Pier Luigi, CAKANA, Andrew, ESSELTINE, Dixie-Lee, MULLIGAN, George, RICCI, Deborah, KARKERA, Jayaprakash D, FAVIS, Reyna, GAFFNEY, Dana, SHAPIRO, Alice, THEOCHAROUS, Panteli, ELSAYED, Yusri A, VAN DE VELDE, Helgi

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