Quantitative systems pharmacology: a promising approach for translational pharmacology von Gadkar, K., Kirouac, D., Parrott, N., Ramanujan, S.

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A Mechanistic Systems Pharmacology Model for Prediction of LDL Cholesterol Lowering by PCSK9 Antagonism in Human Dyslipidemic Populations von Gadkar, K, Budha, N, Baruch, A, Davis, J D, Fielder, P, Ramanujan, S

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A Six‐Stage Workflow for Robust Application of Systems Pharmacology von Gadkar, K, Kirouac, DC, Mager, DE, van der Graaf, PH, Ramanujan, S

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Iterative approach to model identification of biological networks von Gadkar, Kapil G, Gunawan, Rudiyanto, Doyle, 3rd, Francis J

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Clinical responses to ERK inhibitor (GDC-0994) treatment combinations predicted using a Quantitative Systems Pharmacology model of MAPK signaling in BRAF(V600E)-mutant colorectal c... von Kirouac, D, Schaefer, G, Chan, J, Merchant, M, Orr, C, Liu, L, Huang, A, Moffat, J, Gadkar, K, Ramanujan, S

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Type 1 Diabetes PhysioLab® Platform: a validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse von Shoda, L, Kreuwel, H, Gadkar, K, Zheng, Y, Whiting, C, Atkinson, M, Bluestone, J, Mathis, D, Young, D, Ramanujan, S

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Methodologies for Quantitative Systems Pharmacology (QSP) Models: Design and Estimation von Ribba, B, Grimm, HP, Agoram, B, Davies, MR, Gadkar, K, Niederer, S, van Riel, N, Timmis, J, van der Graaf, PH

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Prospective Design of Anti‐Transferrin Receptor Bispecific Antibodies for Optimal Delivery into the Human Brain von Kanodia, JS, Gadkar, K, Bumbaca, D, Zhang, Y, Tong, RK, Luk, W, Hoyte, K, Lu, Y, Wildsmith, KR, Couch, JA, Watts, RJ, Dennis, MS, Ernst, JA, Scearce‐Levie, K, Atwal, JK, Ramanujan, S, Joseph, S

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Cybernetic Model Predictive Control of a Continuous Bioreactor with Cell Recycle von Gadkar, Kapil G., III, Francis J. Doyle, Crowley, Timothy J., Varner, Jeffrey D.

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On-line adaptation of neural networks for bioprocess control von Gadkar, Kapil G., Mehra, Sarika, Gomes, James

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39 - Clinical responses to ERK inhibitor (GDC-0994) treatment combinations predicted using a Quantitative Systems Pharmacology model of MAPK signaling in BRAF(V600E)-mutant colorec... von Kirouac, D., Schaefer, G., Chan, J., Merchant, M., Orr, C., Liu, L., Huang, A., Moffat, J., Gadkar, K., Ramanujan, S.

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Abstract P6-17-20: Withdrawn von Junttila, TT, Ellerman, D, Lombana, N, Hristopoulos, M, Clark, R, Li, J, Vij, R, Koerber, JT, Johnston, J, Shelton, A, Mai, E, Gadkar, K, Lo, AA, Totpal, K, Prell, R, Lee, G, Spiess, C, Slaga, D

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A benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions von Kremling, Andreas, Fischer, Sophia, Gadkar, Kapil, Doyle, Francis J, Sauter, Thomas, Bullinger, Eric, Allgöwer, Frank, Gilles, Ernst D

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Methodologies for Quantitative Systems Pharmacology (QSP) Models: Design and Estimation: Methodologies for Quantitative Systems von Ribba, B, Grimm, HP, Agoram, B, Davies, MR, Gadkar, K, Niederer, S, van Riel, N, Timmis, J, van der Graaf, PH

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Estimating optimal profiles of genetic alterations using constraint-based models von Gadkar, Kapil G., Doyle III, Francis J., Edwards, Jeremy S., Mahadevan, Radhakrishnan

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A Mechanistic Systems Pharmacology Model for Prediction of LDL Cholesterol Lowering by PCSK9 Antagonism in Human Dyslipidemic Populations von Gadkar, K, Budha, N, Baruch, A, Davis, J D, Fielder, P, Ramanujan, S

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In Vivo and In Silico Modeling the Dynamics of Autoimmune Diabetes von Tang, Qizhi, Assistant Adjunct Professor, University of California, San Francisco Diabetes Center, San Francisco, CA, Zheng, Yanan, Engineer, Biological Systems, Entelos, In Silico Research and Development, Foster City, CA, Adams, Jason, MD, Stanford University, Stanford, CA, Kreuwel, Huub, Scientist, Immunologic Diseases, Entelos, In Silico Research and Development, Foster City, CA, Gadkar, Kapil, Biosystems Engineer, Entelos, n Silico Research and Development, Foster City, CA, Penaranda, Cristina, Graduate Student, University of California, San Francisco Diabetes Center, San Francisco, CA, Shoda, Lisl, Senior Scientist, Entelos, In Silico Research and Development, Foster City, CA, Whiting, Chan C., Scientist, Immunologic Diseases, Entelos, In Silico Research and Development, Foster City, CA, Young, Daniel, Dynamics Engineer, Entelos, In Silico Research and Development, Foster City, CA, Bluestone, Jeffrey, Professor, University of California, San Francisco Diabetes Center, San Francisco, CA

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A quantitative systems pharmacology consortium approach to managing immunogenicity of therapeutic proteins von Kierzek, A.M, Hickling, T.P, Figueroa, I, Kalvass, J.C, Nijsen, M, Mohan, K, Veldman, G.M, Yamada, A, Sayama, H, Yokoo, S, Gulati, A, Dhanikula, R.S, Gokemeijer, J, Leil, T.A, Thalhauser, C.J, Giorgi, M, Swat, M.J, Chelliah, V, Small, B.G, Benson, N, Walker, M, Gadkar, K, Quarmby, V, Deng, R, Ferrante, A, Dickinson, G.L, Van Der Walt, J.S, Zhou, L, Chen, X, Jones, H.M, Narula, J, Tourdot, S, Lavé, T, Ribba, B, van der Graaf, P.H

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Methodologies for quantitative systems pharmacology (QSP) models:Design and estimation von Ribba, B, Grimm, H. P, Agoram, B, Davies, M. R, Gadkar, K, Niederer, S, Van Riel, N, Timmis, J, Van Der Graaf, P. H

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Batch control of genetic alterations for optimal metabolic engineering von Gadkar, K.G., Mahadevan, R., Doyle, F.J.

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