Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques von Hazuda, Daria J., Young, Steven D., Guare, James P., Anthony, Neville J., Gomez, Robert P., Wai, John S., Vacca, Joseph P., Handt, Larry, Motzel, Sherri L., Klein, Hilton J., Dornadula, Geethanjali, Danovich, Robert M., Witmer, Marc V., Keith A. A. Wilson, Tussey, Lynda, Schleif, William A., Gabryelski, Lori S., Jin, Lixia, Miller, Michael D., Casimiro, Danilo R., Emini, Emilio A., Shiver, John W.

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Extended Follow-up Confirms Early Vaccine-Enhanced Risk of HIV Acquisition and Demonstrates Waning Effect Over Time Among Participants in a Randomized Trial of Recombinant Adenovir... von Duerr, Ann, Huang, Yunda, Buchbinder, Susan, Coombs, Robert W., Sanchez, Jorge, del Rio, Carlos, Casapia, Martin, Santiago, Steven, Gilbert, Peter, Corey, Lawrence, Robertson, Michael N.

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Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection von Wilcox, Mark H, Gerding, Dale N, Poxton, Ian R, Kelly, Ciaran, Nathan, Richard, Birch, Thomas, Cornely, Oliver A, Rahav, Galia, Bouza, Emilio, Lee, Christine, Jenkin, Grant, Jensen, Werner, Kim, You-Sun, Yoshida, Junichi, Gabryelski, Lori, Pedley, Alison, Eves, Karen, Tipping, Robert, Guris, Dalya, Kartsonis, Nicholas, Dorr, Mary-Beth

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Efficacy of bezlotoxumab based on timing of administration relative to start of antibacterial therapy for Clostridium difficile infection von Birch, Thomas, Golan, Yoav, Rizzardini, Giuliano, Jensen, Erin, Gabryelski, Lori, Guris, Dalya, Dorr, Mary Beth

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Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells von Zhuang, Linghang, Wai, John S, Embrey, Mark W, Fisher, Thorsten E, Egbertson, Melissa S, Payne, Linda S, Guare, James P, Vacca, Joseph P, Hazuda, Daria J, Felock, Peter J, Wolfe, Abigail L, Stillmock, Kara A, Witmer, Marc V, Moyer, Gregory, Schleif, William A, Gabryelski, Lori J, Leonard, Yvonne M, Lynch, Joseph J, Michelson, Stuart R, Young, Steven D

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4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells von Wai, John S, Egbertson, Melissa S, Payne, Linda S, Fisher, Thorsten E, Embrey, Mark W, Tran, Lekhanh O, Melamed, Jeffrey Y, Langford, H. Marie, Guare, James P, Zhuang, Linghang, Grey, Vanessa E, Vacca, Joseph P, Holloway, M. Katharine, Naylor-Olsen, Adel M, Hazuda, Daria J, Felock, Peter J, Wolfe, Abigail L, Stillmock, Kara A, Schleif, William A, Gabryelski, Lori J, Young, Steven D

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In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors von Condra, Jon H, Schleif, William A, Blahy, Olga M, Gabryelski, Lori J, Graham, Donald J, Quintero, Julio, Rhodes, Audrey, Robbins, Helen L, Roth, Elizabeth, Shivaprakash, Malathi, Titus, Donna, Yang, Tao, Tepplert, Hedy, Squires, Kathleen E, Deutsch, Paul J, Emini, Emilio A

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Bezlotoxumab for the Prevention of Recurrent Clostridioides difficile Infection: 12-Month Observational Data From the Randomized Phase III Trial, MODIFY II von Goldstein, Ellie J C, Citron, Diane M, Gerding, Dale N, Wilcox, Mark H, Gabryelski, Lori, Pedley, Alison, Zeng, Zhen, Dorr, Mary Beth

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Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells von Hazuda, Daria J., Felock, Peter, Witmer, Marc, Wolfe, Abigail, Stillmock, Kara, Grobler, Jay A., Espeseth, Amy, Gabryelski, Lori, Schleif, William, Blau, Carol, Miller, Michael D.

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Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs) von Zhao, Zhijian, Wolkenberg, Scott E., Lu, Meiqing, Munshi, Vandna, Moyer, Gregory, Feng, Meizhen, Carella, Anthony V., Ecto, Linda T., Gabryelski, Lori J., Lai, Ming-Tain, Prasad, Sridar G., Yan, Youwei, McGaughey, Georgia B., Miller, Michael D., Lindsley, Craig W., Hartman, George D., Vacca, Joseph P., Williams, Theresa M.

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Vectored Gag and Env but Not Tat Show Efficacy against Simian-Human Immunodeficiency Virus 89.6P Challenge in Mamu-A01-Negative Rhesus Monkeys von Liang, Xiaoping, Casimiro, Danilo R, Schleif, William A, Wang, Fubao, Davies, Mary-Ellen, Zhang, Zhi-Qiang, Fu, Tong-Ming, Finnefrock, Adam C, Handt, Larry, Citron, Michael P, Heidecker, Gwendolyn, Tang, Aimin, Chen, Minchun, Wilson, Keith A, Gabryelski, Lori, McElhaugh, Michael, Carella, Anthony, Moyer, Cheryl, Huang, Lingyi, Vitelli, Salvatore, Patel, Deepa, Lin, Jing, Emini, Emilio A, Shiver, John W

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Amplifying the Voice of the Patient in Clinical Research: Development of Toolkits for Use in Designing and Conducting Patient-Centered Clinical Studies von Elmer, Mary, Florek, Cathy, Gabryelski, Lori, Greene, Alison, Inglis, Anne Marie, Johnson, Karen L., Keiper, Tanja, Ludlam, Sean, Sharpe, T. J., Shay, Kathyjo, Somers, Fabian, Sutherland, Catherine, Teufel, Michele, Yates, Stephen

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A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors von Guare, James P., Wai, John S., Gomez, Robert P., Anthony, Neville J., Jolly, Samson M., Cortes, Amanda R., Vacca, Joseph P., Felock, Peter J., Stillmock, Kara A., Schleif, William A., Moyer, Gregory, Gabryelski, Lori J., Jin, Lixia, Chen, I-Wu, Hazuda, Daria J., Young, Steven D.

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Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection von Wilcox, Mark H, Gerding, Dale N, Poxton, Ian R, Kelly, Ciaran, Nathan, Richard, Birch, Thomas, Cornely, Oliver A, Rahav, Galia, Bouza, Emilio, Lee, Christine, Jenkin, Grant, Jensen, Werner, Kim, You-Sun, Yoshida, Junichi, Gabryelski, Lori, Pedley, Alison, Eves, Karen, Tipping, Robert, Guris, Dalya, Kartsonis, Nicholas, Dorr, Mary-Beth

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Influence of Diagnostic Method on Outcomes in Phase 3 Clinical Trials of Bezlotoxumab for the Prevention of Recurrent Clostridioides difficile Infection: A Post Hoc Analysis of MOD... von Wilcox, Mark H, Rahav, Galia, Dubberke, Erik R, Gabryelski, Lori, Davies, Kerrie, Berry, Claire, Eves, Karen, Ellison, Misoo C, Guris, Dalya, Dorr, Mary Beth

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8-Hydroxy-3,4-dihydropyrrolo[1,2- a]pyrazine-1(2 H)-one HIV-1 integrase inhibitors von Fisher, Thorsten E., Kim, Boyoung, Staas, Donnette D., Lyle, Terry A., Young, Steven D., Vacca, Joseph P., Zrada, Matthew M., Hazuda, Daria J., Felock, Peter J., Schleif, William A., Gabryelski, Lori J., Anari, M. Reza, Kochansky, Christopher J., Wai, John S.

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Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5- a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors von Langford, H. Marie, Williams, Peter D., Homnick, Carl F., Vacca, Joseph P., Felock, Peter J., Stillmock, Kara A., Witmer, Marc V., Hazuda, Daria J., Gabryelski, Lori J., Schleif, William A.

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A series of 5-(5,6)-dihydrouracil substituted 8-hydroxy-[1,6]naphthyridine-7-carboxylic acid 4-fluorobenzylamide inhibitors of HIV-1 integrase and viral replication in cells von Embrey, Mark W., Wai, John S., Funk, Timothy W., Homnick, Carl F., Perlow, Debbie S., Young, Steven D., Vacca, Joseph P., Hazuda, Daria J., Felock, Peter J., Stillmock, Kara A., Witmer, Marc V., Moyer, Gregory, Schleif, William A., Gabryelski, Lori J., Jin, Lixia, Chen, I-Wu, Ellis, Joan D., Wong, Bradley K., Lin, Jiunn H., Leonard, Yvonne M., Tsou, Nancy N., Zhuang, Linghang

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Dihydroxypyridopyrazine-1,6-dione HIV-1 integrase inhibitors von Wai, John S., Kim, Boyoung, Fisher, Thorsten E., Zhuang, Linghang, Embrey, Mark W., Williams, Peter D., Staas, Donnette D., Culberson, Chris, Lyle, Terry A., Vacca, Joseph P., Hazuda, Daria J., Felock, Peter J., Schleif, William A., Gabryelski, Lori J., Jin, Lixia, Chen, I-Wu, Ellis, Joan D., Mallai, Rama, Young, Steven D.

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10-Hydroxy-7,8-dihydropyrazino[1′,2′:1,5]pyrrolo[2,3- d]pyridazine-1,9(2 H,6 H)-diones: Potent, orally bioavailable HIV-1 integrase strand-transfer inhibitors with activity against... von Wiscount, Catherine M., Williams, Peter D., Tran, Lekhanh O., Embrey, Mark W., Fisher, Thorsten E., Sherman, Vanessa, Homnick, Carl F., Donnette Staas, D., Lyle, Terry A., Wai, John S., Vacca, Joseph P., Wang, ZiQiang, Felock, Peter J., Stillmock, Kara A., Witmer, Marc V., Miller, Michael D., Hazuda, Daria J., Day, Alysha M., Gabryelski, Lori J., Ecto, Linda T., Schleif, William A., DiStefano, Daniel J., Kochansky, Christopher J., Reza Anari, M.

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