Rare cancer-specific mutations in PIK3CA show gain of function von Gymnopoulos, Marco, Elsliger, Marc-André, Vogt, Peter K

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Prostate specific membrane antigen (PSMA) expression in primary gliomas and breast cancer brain metastases von Nomura, Natsuko, Pastorino, Sandra, Jiang, Pengfei, Lambert, Gage, Crawford, John R, Gymnopoulos, Marco, Piccioni, David, Juarez, Tiffany, Pingle, Sandeep C, Makale, Milan, Kesari, Santosh

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TR1801‐ADC: a highly potent cMet antibody–drug conjugate with high activity in patient‐derived xenograft models of solid tumors von Gymnopoulos, Marco, Betancourt, Oscar, Blot, Vincent, Fujita, Ryo, Galvan, Diana, Lieuw, Vincent, Nguyen, Sophie, Snedden, Jeanette, Stewart, Christine, Villicana, Jose, Wojciak, Jon, Wong, Eley, Pardo, Raul, Patel, Neki, D’Hooge, Francois, Vijayakrishnan, Balakumar, Barry, Conor, Hartley, John A., Howard, Philip W., Newman, Roland, Coronella, Julia

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Developmental mapping of small-conductance calcium-activated potassium channel expression in the rat nervous system von Gymnopoulos, Marco, Cingolani, Lorenzo A., Pedarzani, Paola, Stocker, Martin

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Cancer-specific mutations in phosphatidylinositol 3-kinase von Vogt, Peter K., Kang, Sohye, Elsliger, Marc-André, Gymnopoulos, Marco

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Eag1 Expression Interferes with Hypoxia Homeostasis and Induces Angiogenesis in Tumors von Downie, Bryan R., Sánchez, Araceli, Knötgen, Hendrik, Contreras-Jurado, Constanza, Gymnopoulos, Marco, Weber, Claudia, Stühmer, Walter, Pardo, Luis A.

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Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation von Denley, Adam, Gymnopoulos, Marco, Kang, Sohye, Mitchell, Christina, Vogt, Peter K

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Addition of N-terminal peptide sequences activates the oncogenic and signaling potentials of the catalytic subunit p110α of phosphoinositide-3-kinase von Sun, Minghao, Hart, Jonathan R., Hillmann, Petra, Gymnopoulos, Marco, Vogt, Peter K.

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A MET Targeting Antibody-Drug Conjugate Overcomes Gemcitabine Resistance in Pancreatic Cancer von Cazes, Alex, Betancourt, Oscar, Esparza, Edgar, Mose, Evangeline S., Jaquish, Dawn, Wong, Eric, Wascher, Alexis A., Tiriac, Herve, Gymnopoulos, Marco, Lowy, Andrew M.

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A novel non-agonist c-Met antibody drug conjugate with superior potency over a c-Met tyrosine kinase inhibitor in c-Met amplified and non-amplified cancers von Fujita, Ryo, Blot, Vincent, Wong, Eley, Stewart, Christine, Lieuw, Vincent, Richardson, Robyn, Banah, Ammar, Villicana, Jose, Timmer, Anjuli, Coronella, Julia, Newman, Roland, Gymnopoulos, Marco

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PI 3-kinase and cancer: changing accents von Vogt, Peter K, Gymnopoulos, Marco, Hart, Jonathan R

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Abstract A58: Bispecific anti-CD3-folate for the treatment of ovarian cancer von Xia, Jinming, deDios, Kristine, Rodrigo, Evelyn, Humphreys, Robin, Wahl, Alan, Gymnopoulos, Marco

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Abstract 225: TR1801-ADC, an optimized anti cMet PBD ADC with high efficacy in solid tumors of the GI tract and head & neck cancer von Gymnopoulos, Marco, Betancourt, Oscar, Blot, Vincent, Fujita, Ryo, Ly, Diana, Nguyen, Sophie, Snedden, Jeanette, Villicana, Jose, Wojciak, Jon, Wong, Eley, Patel, Neki, D'Hooge, Francois, Vijayakrishnan, Balakumar, Barry, Conor, Hartley, John A., Howard, Phil W., Newman, Roland, Coronella, Julia

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Consecutive Steps of Phosphorylation Affect Conformation and DNA Binding of the Chironomus High Mobility Group A Protein von Schwanbeck, Ralf, Gymnopoulos, Marco, Petry, Inga, Piekiełko, Agnieszka, Szewczuk, Zbigniew, Heyduk, Tomasz, Zechel, Kasper, Wiśniewski, Jacek R.

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Recruiting Cytotoxic T Cells to Folate-Receptor-Positive Cancer Cells von Kularatne, Sumith A., Deshmukh, Vishal, Gymnopoulos, Marco, Biroc, Sandra L., Xia, Jinming, Srinagesh, Shailaja, Sun, Ying, Zou, Ning, Shimazu, Mark, Pinkstaff, Jason, Ensari, Semsi, Knudsen, Nick, Manibusan, Anthony, Axup, Jun Y., Kim, Chan Hyuk, Smider, Vaughn V., Javahishvili, Tsotne, Schultz, Peter G.

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Abstract LB025: First disclosure of AZD5335, a TOP1i-ADC targeting low and high FRα-expressing ovarian cancer with superior preclinical activity vs FRα-MTI ADC von Gymnopoulos, Marco, Thomas, Tima, Gasper, Diana, Anderton, Judith, Tammali, Ravinder, Rosfjord, Ed, Durham, Nick, Ward, Chris, Myers, Claire, Wang, Jixin, Zhong, Wenyan, Christ, Simon, Meinecke, Lina, Nekolla, Katharina, Monasor, Laura Sebastian, Dodd, Roger, Patel, Neki, Albertella, Mark, Zeron-Medina, Jorge, Fraenkel, Paula, Sapra, Puja

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Abstract 2947: Preclinical evaluation of a novel B7-H4 targeted antibody-drug conjugate AZD8205 as a single agent and in combination with novel PARP inhibitor and checkpoint blocka... von Cazes, Alex, Kinneer, Krista, Omar, Bilal, Chesebrough, Jon, Anderton, Judith, Wang, Jixin, Staniszewska, Anna D., Arbitman, Steven, Daita, Kalyani, Desai, Himanshi, Johnson, Yoshimi, Rothstein, Raymond, Gymnopoulos, Marco, Fabbri, Giulia, Cooper, Zachary A., Albertella, Mark, Hammond, Scott A., Cosulich, Sabina, Luheshi, Nadia, Sapra, Puja

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Developmental Regulation of Small-Conductance Ca2+-Activated K+ Channel Expression and Function in Rat Purkinje Neurons von Cingolani, Lorenzo A, Gymnopoulos, Marco, Boccaccio, Anna, Stocker, Martin, Pedarzani, Paola

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Abstract 668: Folate conjugated site-specifically to anti-human-CD3-Fab is efficacious in mouse models of ovarian cancer von Biroc, Sandra L., Gymnopoulos, Marco, Srinagesh, Shailaja, Hayes, Brad, Knudsen, Nick, Manibusan, Anthony, Pinkstaff, Jason, Buss, Tim, Cox, Kari, Marsden, Robin, Skidmore, Lillian, Xia, Jinming, Sun, Ying, Zou, Ning, Javahishvili, Tsotne

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Folate Receptor–Targeted T cells for Cancer Immunotherapy von Kularatne, Sumith A., Deshmukh, Vishal, Gymnopoulos, Marco, Biroc, Sandra L., Xia, Jinming, Srinagesh, Shaila, Sun, Ying, Zou, Ning, Shimazu, Mark, Pinkstaff, Jason, Ensari, Semsi, Knudsen, Nick, Manibusan, Anthony, Axup, Jun, Kim, Chanhyuk, Smider, Vaughn, Javahishvili, Tsotne, Schultz, Peter G.

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