CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations von Höijer, Ida, Emmanouilidou, Anastasia, Östlund, Rebecka, van Schendel, Robin, Bozorgpana, Selma, Tijsterman, Marcel, Feuk, Lars, Gyllensten, Ulf, den Hoed, Marcel, Ameur, Adam

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Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan von Johansson, Asa, Enroth, Stefan, Gyllensten, Ulf

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Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia von Halvorsen, Matthew, Huh, Ruth, Oskolkov, Nikolay, Wen, Jia, Netotea, Sergiu, Giusti-Rodriguez, Paola, Karlsson, Robert, Bryois, Julien, Nystedt, Björn, Ameur, Adam, Kähler, Anna K., Ancalade, NaEshia, Farrell, Martilias, Crowley, James J., Li, Yun, Magnusson, Patrik K. E., Gyllensten, Ulf, Hultman, Christina M., Sullivan, Patrick F., Szatkiewicz, Jin P.

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The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly von Pinese, Mark, Lacaze, Paul, Rath, Emma M., Stone, Andrew, Brion, Marie-Jo, Ameur, Adam, Nagpal, Sini, Puttick, Clare, Husson, Shane, Degrave, Dmitry, Cristina, Tina Navin, Kahl, Vivian F. S., Statham, Aaron L., Woods, Robyn L., McNeil, John J., Riaz, Moeen, Barr, Margo, Nelson, Mark R., Reid, Christopher M., Murray, Anne M., Shah, Raj C., Wolfe, Rory, Atkins, Joshua R., Fitzsimmons, Chantel, Cairns, Heath M., Green, Melissa J., Carr, Vaughan J., Cowley, Mark J., Pickett, Hilda A., James, Paul A., Powell, Joseph E., Kaplan, Warren, Gibson, Greg, Gyllensten, Ulf, Cairns, Murray J., McNamara, Martin, Dinger, Marcel E., Thomas, David M.

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Immune cells lacking Y chromosome show dysregulation of autosomal gene expression von Dumanski, Jan P., Halvardson, Jonatan, Davies, Hanna, Rychlicka-Buniowska, Edyta, Mattisson, Jonas, Moghadam, Behrooz Torabi, Nagy, Noemi, Węglarczyk, Kazimierz, Bukowska-Strakova, Karolina, Danielsson, Marcus, Olszewski, Paweł, Piotrowski, Arkadiusz, Oerton, Erin, Ambicka, Aleksandra, Przewoźnik, Marcin, Bełch, Łukasz, Grodzicki, Tomasz, Chłosta, Piotr L., Imreh, Stefan, Giedraitis, Vilmantas, Kilander, Lena, Nordlund, Jessica, Ameur, Adam, Gyllensten, Ulf, Johansson, Åsa, Józkowicz, Alicja, Siedlar, Maciej, Klich-Rączka, Alicja, Jaszczyński, Janusz, Enroth, Stefan, Baran, Jarosław, Ingelsson, Martin, Perry, John R. B., Ryś, Janusz, Forsberg, Lars A.

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Cost-effectiveness analysis of repeated self-sampling for HPV testing in primary cervical screening: a randomized study von Aarnio, Riina, Ostensson, Ellinor, Olovsson, Matts, Gustavsson, Inger, Gyllensten, Ulf

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Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease von Folkersen, Lasse, Fauman, Eric, Sabater-Lleal, Maria, Strawbridge, Rona J, Frånberg, Mattias, Sennblad, Bengt, Baldassarre, Damiano, Veglia, Fabrizio, Humphries, Steve E, Rauramaa, Rainer, de Faire, Ulf, Smit, Andries J, Giral, Philippe, Kurl, Sudhir, Mannarino, Elmo, Enroth, Stefan, Johansson, Åsa, Enroth, Sofia Bosdotter, Gustafsson, Stefan, Lind, Lars, Lindgren, Cecilia, Morris, Andrew P, Giedraitis, Vilmantas, Silveira, Angela, Franco-Cereceda, Anders, Tremoli, Elena, Gyllensten, Ulf, Ingelsson, Erik, Brunak, Søren, Eriksson, Per, Ziemek, Daniel, Hamsten, Anders, Mälarstig, Anders

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Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs von Enroth, Stefan, Johansson, Åsa, Enroth, Sofia Bosdotter, Gyllensten, Ulf

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The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases von Ahsan, Muhammad, Ek, Weronica E, Rask-Andersen, Mathias, Karlsson, Torgny, Lind-Thomsen, Allan, Enroth, Stefan, Gyllensten, Ulf, Johansson, Åsa

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Comparison of vaginal self‐sampling and cervical sampling by medical professionals for the detection of HPV and CIN2+: A randomized study von Aarnio, Riina, Isacson, Isabella, Sanner, Karin, Gustavsson, Inger, Gyllensten, Ulf, Olovsson, Matts

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Next generation pan-cancer blood proteome profiling using proximity extension assay von Álvez, María Bueno, Edfors, Fredrik, von Feilitzen, Kalle, Zwahlen, Martin, Mardinoglu, Adil, Edqvist, Per-Henrik, Sjöblom, Tobias, Lundin, Emma, Rameika, Natallia, Enblad, Gunilla, Lindman, Henrik, Höglund, Martin, Hesselager, Göran, Stålberg, Karin, Enblad, Malin, Simonson, Oscar E., Häggman, Michael, Axelsson, Tomas, Åberg, Mikael, Nordlund, Jessica, Zhong, Wen, Karlsson, Max, Gyllensten, Ulf, Ponten, Fredrik, Fagerberg, Linn, Uhlén, Mathias

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Human papillomavirus prevalence and risk factors among HIV-negative and HIV-positive women residing in rural Eastern Cape, South Africa von Taku, Ongeziwe, Businge, Charles B., Mdaka, Mana L., Phohlo, Keletso, Basera, Wisdom, Garcia-Jardon, Mirta, Meiring, Tracy L., Gyllensten, Ulf, Williamson, Anna-Lise, Mbulawa, Zizipho Z.A.

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Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability von Kierczak, Marcin, Rafati, Nima, Höglund, Julia, Gourlé, Hadrien, Lo Faro, Valeria, Schmitz, Daniel, Ek, Weronica E., Gyllensten, Ulf, Enroth, Stefan, Ekman, Diana, Nystedt, Björn, Karlsson, Torgny, Johansson, Åsa

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High throughput proteomics identifies a high-accuracy 11 plasma protein biomarker signature for ovarian cancer von Enroth, Stefan, Berggrund, Malin, Lycke, Maria, Broberg, John, Lundberg, Martin, Assarsson, Erika, Olovsson, Matts, Stålberg, Karin, Sundfeldt, Karin, Gyllensten, Ulf

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Acceptability of self- collection for human papillomavirus detection in the Eastern Cape, South Africa von Taku, Ongeziwe, Meiring, Tracy L., Gustavsson, Inger, Phohlo, Keletso, Garcia-Jardon, Mirta, Mbulawa, Zizipho Z. A., Businge, Charles B., Gyllensten, Ulf, Williamson, Anna-Lise

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KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference von Schumann, Gunter, O’Reilly, Paul, Gao, He, Xu, Bing, Ruggeri, Barbara, Preis, Sarah, Lepe, Marcelo Segura, Akira, Shizuo, Barbieri, Caterina, Baumeister, Sebastian, Cauchi, Stephane, Clarke, Toni-Kim, Enroth, Stefan, Fische, Kristar, Harris, Sarah E., Hieber, Saskia, Johansson, Åsa, Laitinen, Jaana, Loukola, Anu, Luan, Jian’an, Lyytikäinen, Leo-Pekka, Mangino, Massimo, Mbarek, Hamdi, Milaneschi, Yuri, Nelson, Christopher, Nettleton, Jennifer, Partinen, Eemil, Rawal, Rajesh, Robino, Antonietta, Rose, Lynda, Sala, Cinzia, Satoh, Takashi, Schmidt, Reinhold, Schraut, Katharina, Scott, Robert, Starr, John M., Trompet, Stella, Uitterlinden, André G., Venturini, Cristina, Vergnaud, Anne-Claire, Vitart, Veronique, Vuckovic, Dragana, Wedenoja, Juho, Yengo, Loic, Yu, Bing, Zhang, Weihua, Zhao, Jing Hua, Boomsma, Dorret I., Chambers, John, de Geus, Eco, Eriksson, Johan G., Esko, Tõnu, Eulenburg, Volker, Franco, Oscar H., Froguel, Philippe, Gieger, Christian, Grabe, Hans J., Gudnason, Vilmundur, Gyllensten, Ulf, Harris, Tamara B., Hartikainen, Anna-Liisa, Heath, Andrew C., Hocking, Lynne, Hofman, Albert, Huth, Cornelia, Jarvelin, Marjo-Riitta, Jukema, J. Wouter, Kutalik, Zoltan, Lahti, Jari, Lehtimäki, Terho, Liu, Yongmei, Madden, Pamela A. F., Martin, Nicholas, Morrison, Alanna, Penninx, Brenda, Pirastu, Nicola, Psaty, Bruce, Raitakari, Olli, Rose, Richard, Rotter, Jerome I., Samani, Nilesh J., Spector, Tim D., Stott, David, Strachan, David, Tzoulaki, Ioanna, van der Harst, Pim, van Duijn, Cornelia M., Marques-Vidal, Pedro, Vollenweider, Peter, Wareham, Nicholas J., Whitfield, John B., Wilson, James, Bakalkin, Georgy, Evangelou, Evangelos, Liu, Yun, Desrivières, Sylvane, Mangelsdorf, David J., Müller, Christian P., Levy, Daniel, Elliott, Paul

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SweGen: a whole-genome data resource of genetic variability in a cross-section of the Swedish population von Ameur, Adam, Dahlberg, Johan, Olason, Pall, Vezzi, Francesco, Karlsson, Robert, Martin, Marcel, Viklund, Johan, Kähäri, Andreas Kusalananda, Lundin, Pär, Che, Huiwen, Thutkawkorapin, Jessada, Eisfeldt, Jesper, Lampa, Samuel, Dahlberg, Mats, Hagberg, Jonas, Jareborg, Niclas, Liljedahl, Ulrika, Jonasson, Inger, Johansson, Åsa, Feuk, Lars, Lundeberg, Joakim, Syvänen, Ann-Christine, Lundin, Sverker, Nilsson, Daniel, Nystedt, Björn, Magnusson, Patrik Ke, Gyllensten, Ulf

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Diagnostic excision of the cervix in women over 40 years with human papilloma virus persistency and normal cytology von Aarnio, Riina, Wikström, Ingrid, Gustavsson, Inger, Gyllensten, Ulf, Olovsson, Matts

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Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets von Wain, Louise V, Shrine, Nick, Artigas, María Soler, Erzurumluoglu, A Mesut, Bossini-Castillo, Lara, Obeidat, Ma'en, Henry, Amanda P, Billington, Charlotte K, Rimington, Tracy L, Fenech, Anthony G, John, Catherine, Blake, Tineka, Jackson, Victoria E, Allen, Richard J, Prins, Bram P, Campbell, Archie, Porteous, David J, Jarvelin, Marjo-Riitta, Wielscher, Matthias, Hui, Jennie, Wareham, Nicholas J, Zhao, Jing Hua, Wilson, James F, Joshi, Peter K, Stubbe, Beate, Rawal, Rajesh, Schulz, Holger, Imboden, Medea, Probst-Hensch, Nicole M, Karrasch, Stefan, Gieger, Christian, Deary, Ian J, Harris, Sarah E, Marten, Jonathan, Rudan, Igor, Enroth, Stefan, Gyllensten, Ulf, Kerr, Shona M, Polasek, Ozren, Surakka, Ida, Vitart, Veronique, Hayward, Caroline, Lehtimäki, Terho, Raitakari, Olli T, Evans, David M, Henderson, A John, Pennell, Craig E, Wang, Carol A, Sly, Peter D, Wan, Emily S, Busch, Robert, Hobbs, Brian D, Litonjua, Augusto A, Sparrow, David W, Gulsvik, Amund, Bakke, Per S, Crapo, James D, Beaty, Terri H, Hansel, Nadia N, Mathias, Rasika A, Ruczinski, Ingo, Barnes, Kathleen C, Bossé, Yohan, Joubert, Philippe, van den Berge, Maarten, Brandsma, Corry-Anke, Paré, Peter D, Sin, Don D, Nickle, David C, Hao, Ke, Gottesman, Omri, Dewey, Frederick E, Bruse, Shannon E, Carey, David J, Kirchner, H Lester, Jonsson, Stefan, Thorleifsson, Gudmar, Jonsdottir, Ingileif, Gislason, Thorarinn, Stefansson, Kari, Schurmann, Claudia, Nadkarni, Girish, Bottinger, Erwin P, Loos, Ruth J F, Walters, Robin G, Chen, Zhengming, Millwood, Iona Y, Vaucher, Julien, Kurmi, Om P, Li, Liming, Hansell, Anna L, Brightling, Chris, Zeggini, Eleftheria, Cho, Michael H, Silverman, Edwin K, Sayers, Ian, Trynka, Gosia, Morris, Andrew P, Strachan, David P, Hall, Ian P

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Cervical dysplasia in elderly women performing repeated self-sampling for HPV testing von Lindström, Annika Kristina, Hermansson, Ruth Sanchez, Gustavsson, Inger, Hedlund Lindberg, Julia, Gyllensten, Ulf, Olovsson, Matts

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