Format and geometries matter: Structure-based design defines the functionality of bispecific antibodies von Dickopf, Steffen, Georges, Guy J., Brinkmann, Ulrich

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The H3 loop of antibodies shows unique structural characteristics von Regep, Cristian, Georges, Guy, Shi, Jiye, Popovic, Bojana, Deane, Charlotte M.

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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome von Richter, Hans, Satz, Alexander L, Bedoucha, Marc, Buettelmann, Bernd, Petersen, Ann C, Harmeier, Anja, Hermosilla, Ricardo, Hochstrasser, Remo, Burger, Dominique, Gsell, Bernard, Gasser, Rodolfo, Huber, Sylwia, Hug, Melanie N, Kocer, Buelent, Kuhn, Bernd, Ritter, Martin, Rudolph, Markus G, Weibel, Franziska, Molina-David, Judith, Kim, Jin-Ju, Santos, Javier Varona, Stihle, Martine, Georges, Guy J, Bonfil, R. Daniel, Fridman, Rafael, Uhles, Sabine, Moll, Solange, Faul, Christian, Fornoni, Alessia, Prunotto, Marco

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SAbPred: a structure-based antibody prediction server von Dunbar, James, Krawczyk, Konrad, Leem, Jinwoo, Marks, Claire, Nowak, Jaroslaw, Regep, Cristian, Georges, Guy, Kelm, Sebastian, Popovic, Bojana, Deane, Charlotte M

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ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins von Abanades, Brennan, Wong, Wing Ki, Boyles, Fergus, Georges, Guy, Bujotzek, Alexander, Deane, Charlotte M.

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Targeted chain-exchange-mediated reconstitution of a split type-I cytokine for conditional immunotherapy von Vasic, Vedran, Buldun, Can, Ritz, Manfred, Dickopf, Steffen, Georges, Guy J., Spick, Christian, Peuker, Alessa, Meier, Thomas, Mayer, Klaus, Brinkmann, Ulrich

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Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies von Schaefer, Wolfgang, Regula, Jörg T, Bähner, Monika, Schanzer, Jürgen, Croasdale, Rebecca, Dürr, Harald, Gassner, Christian, Georges, Guy, Kettenberger, Hubert, Imhof-Jung, Sabine, Schwaiger, Manfred, Stubenrauch, Kay G, Sustmann, Claudio, Thomas, Markus, Scheuer, Werner, Klein, Christian

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Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices von Dengl, Stefan, Mayer, Klaus, Bormann, Felix, Duerr, Harald, Hoffmann, Eike, Nussbaum, Bianca, Tischler, Michael, Wagner, Martina, Kuglstatter, Andreas, Leibrock, Lea, Buldun, Can, Georges, Guy, Brinkmann, Ulrich

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Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies von Niederfellner, Gerhard, Lammens, Alfred, Mundigl, Olaf, Georges, Guy J., Schaefer, Wolfgang, Schwaiger, Manfred, Franke, Andreas, Wiechmann, Kornelius, Jenewein, Stefan, Slootstra, Jerry W., Timmerman, Peter, Brännström, Annika, Lindstrom, Frida, Mössner, Ekkehard, Umana, Pablo, Hopfner, Karl-Peter, Klein, Christian

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In vitro and in vivo degradation of microfiber bioresorbable coronary scaffold von Huang, Chi-Hung, Lee, Sheng-Yang, Horng, Sonida, Guy, Louis-Georges, Yu, Ting-Bin

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Ensembles in solution as a new paradigm for antibody structure prediction and design von Fernández-Quintero, Monica L., Georges, Guy, Varga, Janos M., Liedl, Klaus R.

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Prediction of VH-VL domain orientation for antibody variable domain modeling von Bujotzek, Alexander, Dunbar, James, Lipsmeier, Florian, Schäfer, Wolfgang, Antes, Iris, Deane, Charlotte M., Georges, Guy

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SCALOP: sequence-based antibody canonical loop structure annotation von Wong, Wing Ki, Georges, Guy, Ros, Francesca, Kelm, Sebastian, Lewis, Alan P, Taddese, Bruck, Leem, Jinwoo, Deane, Charlotte M

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Assessing developability early in the discovery process for novel biologics von Fernández-Quintero, Monica L., Ljungars, Anne, Waibl, Franz, Greiff, Victor, Andersen, Jan Terje, Gjølberg, Torleif T., Jenkins, Timothy P., Voldborg, Bjørn Gunnar, Grav, Lise Marie, Kumar, Sandeep, Georges, Guy, Kettenberger, Hubert, Liedl, Klaus R., Tessier, Peter M., McCafferty, John, Laustsen, Andreas H.

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Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope von Wong, Wing Ki, Robinson, Sarah A., Bujotzek, Alexander, Georges, Guy, Lewis, Alan P., Shi, Jiye, Snowden, James, Taddese, Bruck, Deane, Charlotte M.

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Germline-Dependent Antibody Paratope States and Pairing Specific VH-VL Interface Dynamics von Fernández-Quintero, Monica L., Kroell, Katharina B., Bacher, Lisa M., Loeffler, Johannes R., Quoika, Patrick K., Georges, Guy, Bujotzek, Alexander, Kettenberger, Hubert, Liedl, Klaus R.

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Evaluation of Magnesium-based Medical Devices in Preclinical Studies: Challenges and Points to Consider von Chagnon, Madeleine, Guy, Louis-Georges, Jackson, Nicolette

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VH-VL orientation prediction for antibody humanization candidate selection: A case study von Bujotzek, Alexander, Lipsmeier, Florian, Harris, Seth F, Benz, Jörg, Kuglstatter, Andreas, Georges, Guy

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Procollagen-lysine 2-oxoglutarate 5-dioxygenases are responsible for 5R-hydroxylysine modification of therapeutic T-cell bispecific monoclonal antibodies produced by Chinese hamste... von Bauer, Niels, Boettger, Marco, Papadaki, Styliani, Leitner, Tanja, Klostermann, Stefan, Kettenberger, Hubert, Georges, Guy, Larraillet, Vincent, Gluhacevic von Kruechten, Dino, Hillringhaus, Lars, Vogt, Annette, Ausländer, Simon, Popp, Oliver

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Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime von Moll, Solange, Yasui, Yukari, Abed, Ahmed, Murata, Takeshi, Shimada, Hideaki, Maeda, Akira, Fukushima, Naoshi, Kanamori, Masakazu, Uhles, Sabine, Badi, Laura, Cagarelli, Thomas, Formentini, Ivan, Drawnel, Faye, Georges, Guy, Bergauer, Tobias, Gasser, Rodolfo, Bonfil, R Daniel, Fridman, Rafael, Richter, Hans, Funk, Juergen, Moeller, Marcus J, Chatziantoniou, Christos, Prunotto, Marco

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