Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages von Obradovic, Aleksandar, Chowdhury, Nivedita, Haake, Scott M., Ager, Casey, Wang, Vinson, Vlahos, Lukas, Guo, Xinzheng V., Aggen, David H., Rathmell, W. Kimryn, Jonasch, Eric, Johnson, Joyce E., Roth, Marc, Beckermann, Kathryn E., Rini, Brian I., McKiernan, James, Califano, Andrea, Drake, Charles G.

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Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19 von Szabo, Peter A., Dogra, Pranay, Gray, Joshua I., Wells, Steven B., Connors, Thomas J., Weisberg, Stuart P., Krupska, Izabela, Matsumoto, Rei, Poon, Maya M.L., Idzikowski, Emma, Morris, Sinead E., Pasin, Chloé, Yates, Andrew J., Ku, Amy, Chait, Michael, Davis-Porada, Julia, Guo, Xinzheng V., Zhou, Jing, Steinle, Matthew, Mackay, Sean, Saqi, Anjali, Baldwin, Matthew R., Sims, Peter A., Farber, Donna L.

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Development of a Comprehensive Antibody Staining Database Using a Standardized Analytics Pipeline von Amir, El-Ad David, Lee, Brian, Badoual, Paul, Gordon, Martin, Guo, Xinzheng V, Merad, Miriam, Rahman, Adeeb H

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Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice von Goodsmith, Nichole, Guo, Xinzheng V, Vandal, Omar H, Vaubourgeix, Julien, Wang, Ruojun, Botella, Hélène, Song, Shuang, Bhatt, Kamlesh, Liba, Amir, Salgame, Padmini, Schnappinger, Dirk, Ehrt, Sabine

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Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike von Liu, Lihong, Wang, Pengfei, Nair, Manoj S., Yu, Jian, Rapp, Micah, Wang, Qian, Luo, Yang, Chan, Jasper F.-W., Sahi, Vincent, Figueroa, Amir, Guo, Xinzheng V., Cerutti, Gabriele, Bimela, Jude, Gorman, Jason, Zhou, Tongqing, Chen, Zhiwei, Yuen, Kwok-Yung, Kwong, Peter D., Sodroski, Joseph G., Yin, Michael T., Sheng, Zizhang, Huang, Yaoxing, Shapiro, Lawrence, Ho, David D.

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Silencing Essential Protein Secretion in Mycobacterium smegmatis by Using Tetracycline Repressors von GUO, Xinzheng V, MONTELEONE, Mercedes, KLOTZSCHE, Marcus, KAMIONKA, Annette, HILLEN, Wolfgang, BRAUNSTEIN, Miriam, EHRT, Sabine, SCHNAPPINGER, Dirk

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Neoadjuvant chemoradiation alters the immune microenvironment in pancreatic ductal adenocarcinoma von Gartrell, Robyn D, Enzler, Thomas, Kim, Pan S, Fullerton, Benjamin T, Fazlollahi, Ladan, Chen, Andrew X, Minns, Hanna E, Perni, Subha, Weisberg, Stuart P, Rizk, Emanuelle M, Wang, Samuel, Oh, Eun Jeong, Guo, Xinzheng V, Chiuzan, Codruta, Manji, Gulam A, Bates, Susan E, Chabot, John, Schrope, Beth, Kluger, Michael, Emond, Jean, Rabadán, Raul, Farber, Donna, Remotti, Helen E, Horowitz, David P, Saenger, Yvonne M

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A molecular single-cell lung atlas of lethal COVID-19 von Melms, Johannes C., Biermann, Jana, Huang, Huachao, Wang, Yiping, Nair, Ajay, Tagore, Somnath, Katsyv, Igor, Rendeiro, André F., Amin, Amit Dipak, Schapiro, Denis, Frangieh, Chris J., Luoma, Adrienne M., Filliol, Aveline, Fang, Yinshan, Ravichandran, Hiranmayi, Clausi, Mariano G., Alba, George A., Rogava, Meri, Chen, Sean W., Ho, Patricia, Montoro, Daniel T., Kornberg, Adam E., Han, Arnold S., Bakhoum, Mathieu F., Anandasabapathy, Niroshana, Suárez-Fariñas, Mayte, Bakhoum, Samuel F., Bram, Yaron, Borczuk, Alain, Guo, Xinzheng V., Lefkowitch, Jay H., Marboe, Charles, Lagana, Stephen M., Del Portillo, Armando, Tsai, Emily J., Zorn, Emmanuel, Markowitz, Glen S., Schwabe, Robert F., Schwartz, Robert E., Elemento, Olivier, Saqi, Anjali, Hibshoosh, Hanina, Que, Jianwen, Izar, Benjamin

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Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses von Aggen, David H, Ager, Casey R, Obradovic, Aleksandar Z, Chowdhury, Nivedita, Ghasemzadeh, Ali, Mao, Wendy, Chaimowitz, Matthew G, Lopez-Bujanda, Zoila A, Spina, Catherine S, Hawley, Jessica E, Dallos, Matthew C, Zhang, Cheng, Wang, Vinson, Li, Hu, Guo, Xinzheng V, Drake, Charles G

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Anti-PD-1 immunotherapy with androgen deprivation therapy induces robust immune infiltration in metastatic castration-sensitive prostate cancer von Hawley, Jessica E., Obradovic, Aleksandar Z., Dallos, Matthew C., Lim, Emerson A., Runcie, Karie, Ager, Casey R., McKiernan, James, Anderson, Christopher B., Decastro, Guarionex J., Weintraub, Joshua, Virk, Renu, Lowy, Israel, Hu, Jianhua, Chaimowitz, Matthew G., Guo, Xinzheng V., Zhang, Ya, Haffner, Michael C., Worley, Jeremy, Stein, Mark N., Califano, Andrea, Drake, Charles G.

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Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool von Fu, Jianing, Zuber, Julien, Martinez, Mercedes, Shonts, Brittany, Obradovic, Aleksandar, Wang, Hui, Lau, Sai-ping, Xia, Amy, Waffarn, Elizabeth E., Frangaj, Kristjana, Savage, Thomas M., Simpson, Michael T., Yang, Suxiao, Guo, Xinzheng V., Miron, Michelle, Senda, Takashi, Rogers, Kortney, Rahman, Adeeb, Ho, Siu-hong, Shen, Yufeng, Griesemer, Adam, Farber, Donna L., Kato, Tomoaki, Sykes, Megan

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Plasticity of intragraft alloreactive T cell clones in human gut correlates with transplant outcomes von Fu, Jianing, Wang, Zicheng, Martinez, Mercedes, Obradovic, Aleksandar, Jiao, Wenyu, Frangaj, Kristjana, Jones, Rebecca, Guo, Xinzheng V, Zhang, Ya, Kuo, Wan-I, Ko, Huaibin M, Iuga, Alina, Bay Muntnich, Constanza, Prada Rey, Adriana, Rogers, Kortney, Zuber, Julien, Ma, Wenji, Miron, Michelle, Farber, Donna L, Weiner, Joshua, Kato, Tomoaki, Shen, Yufeng, Sykes, Megan

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Average Overlap Frequency: A simple metric to evaluate staining quality and community identification in high dimensional mass cytometry experiments von Amir, El-ad David, Guo, Xinzheng V., Mayovska, Oksana, Rahman, Adeeb H.

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Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor von Ehrt, Sabine, Guo, Xinzheng V., Hickey, Christopher M., Ryou, Marvin, Monteleone, Mercedes, Riley, Lee W., Schnappinger, Dirk

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Author Correction: A molecular single-cell lung atlas of lethal COVID-19 von Melms, Johannes C., Biermann, Jana, Huang, Huachao, Wang, Yiping, Nair, Ajay, Tagore, Somnath, Katsyv, Igor, Rendeiro, André F., Amin, Amit Dipak, Schapiro, Denis, Frangieh, Chris J., Luoma, Adrienne M., Filliol, Aveline, Fang, Yinshan, Ravichandran, Hiranmayi, Clausi, Mariano G., Alba, George A., Rogava, Meri, Chen, Sean W., Ho, Patricia, Montoro, Daniel T., Kornberg, Adam E., Han, Arnold S., Bakhoum, Mathieu F., Anandasabapathy, Niroshana, Suárez-Fariñas, Mayte, Bakhoum, Samuel F., Bram, Yaron, Borczuk, Alain, Guo, Xinzheng V., Lefkowitch, Jay H., Marboe, Charles, Lagana, Stephen M., Del Portillo, Armando, Tsai, Emily J., Zorn, Emmanuel, Markowitz, Glen S., Schwabe, Robert F., Schwartz, Robert E., Elemento, Olivier, Saqi, Anjali, Hibshoosh, Hanina, Que, Jianwen, Izar, Benjamin

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A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter‐Instrument Variability of the Helios Mass Cytometer von Lee, Brian H., Kelly, Geoffrey, Bradford, Shermineh, Davila, Melanie, Guo, Xinzheng V., Amir, El‐Ad David, Thrash, Emily M., Solga, Michael D., Lannigan, Joanne, Sellers, Brian, Candia, Julian, Tsang, John, Montgomery, Ruth R., Tamaki, Stanley J., Sigdel, Tara K., Sarwal, Minnie M., Lanier, Lewis L., Tian, Yuan, Kim, Cheryl, Hinz, Denise, Peters, Bjoern, Sette, Alessandro, Rahman, Adeeb H.

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Abstract PO-024: Tumor-specific cell populations in clear cell renal carcinoma associated with clinical outcome identified using single-cell protein activity inference von Obradovic, Aleksandar, Showdhury, Nivedita, Ager, Casey, Wang, Vinson, Vlahos, Lukas, Guo, Xinzheng V., Aggen, David H., McKiernan, James, Califano, Andrea, Drake, Charles G.

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Disruption of an M. tuberculosis Membrane Protein Causes a Magnesium-dependent Cell Division Defect and Failure to Persist in Mice: e1004645 von Goodsmith, Nichole, Guo, Xinzheng V, Vandal, Omar H, Vaubourgeix, Julien, Wang, Ruojun, Botella, Hélène, Song, Shuang, Bhatt, Kamlesh, Liba, Amir, Salgame, Padmini, Schnappinger, Dirk, Ehrt, Sabine

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Silencing Mycobacterium smegmatis by using tetracycline repressors von Guo, Xinzheng V, Monteleone, Mercedes, Klotzsche, Marcus, Kamionka, Annette, Hillen, Wolfgang, Braunstein, Miriam, Ehrt, Sabine, Schnappinger, Dirk

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Neoadjuvant chemoradiation alters the immune microenvironment in pancreatic ductal adenocarcinoma von Gartrell, Robyn D., Enzler, Thomas, Kim, Pan S., Fullerton, Benjamin T., Fazlollahi, Ladan, Chen, Andrew X., Minns, Hanna E., Perni, Subha, Weisberg, Stuart P., Rizk, Emanuelle M., Wang, Samuel, Oh, Eun Jeong, Guo, Xinzheng V., Chiuzan, Codruta, Manji, Gulam A., Bates, Susan E., Chabot, John, Schrope, Beth, Kluger, Michael, Emond, Jean, Rabadán, Raul, Farber, Donna, Remotti, Helen E., Horowitz, David P., Saenger, Yvonne M.

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