Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo von Lehmann, Mareike, Korfei, Martina, Mutze, Kathrin, Klee, Stephan, Skronska-Wasek, Wioletta, Alsafadi, Hani N, Ota, Chiharu, Costa, Rita, Schiller, Herbert B, Lindner, Michael, Wagner, Darcy E, Günther, Andreas, Königshoff, Melanie

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Model‐Based Drug–Drug Interaction Extrapolation Strategy From Adults to Children: Risdiplam in Pediatric Patients With Spinal Muscular Atrophy von Cleary, Yumi, Gertz, Michael, Grimsey, Paul, Günther, Andreas, Heinig, Katja, Ogungbenro, Kayode, Aarons, Leon, Galetin, Aleksandra, Kletzl, Heidemarie

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Ocrelizumab in relapsing and primary progressive multiple sclerosis: Pharmacokinetic and pharmacodynamic analyses of OPERA I, OPERA II and ORATORIO von Gibiansky, Ekaterina, Petry, Claire, Mercier, Francois, Günther, Andreas, Herman, Ann, Kappos, Ludwig, Hauser, Stephen, Yamamoto, Yumi, Wang, Qing, Model, Fabian, Kletzl, Heidemarie

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Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD von Baarsma, Hoeke A, Skronska-Wasek, Wioletta, Mutze, Kathrin, Ciolek, Florian, Wagner, Darcy E, John-Schuster, Gerrit, Heinzelmann, Katharina, Günther, Andreas, Bracke, Ken R, Dagouassat, Maylis, Boczkowski, Jorge, Brusselle, Guy G, Smits, Ron, Eickelberg, Oliver, Yildirim, Ali Ö, Königshoff, Melanie

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WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis von Königshoff, Melanie, Kramer, Monika, Balsara, Nisha, Wilhelm, Jochen, Amarie, Oana Veronica, Jahn, Andreas, Rose, Frank, Fink, Ludger, Seeger, Werner, Schaefer, Liliana, Günther, Andreas, Eickelberg, Oliver

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Exploring efficacy and safety of oral Pirfenidone for progressive, non-IPF lung fibrosis (RELIEF) - a randomized, double-blind, placebo-controlled, parallel group, multi-center, ph... von Behr, Jürgen, Neuser, Petra, Prasse, Antje, Kreuter, Michael, Rabe, Klaus, Schade-Brittinger, Carmen, Wagner, Jasmin, Günther, Andreas

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Entrepreneurial Strategies of Professional Service Firms: An Analysis of Commercial Law Firm Spin-Offs in Germany von Gunther, Andreas B

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A phase 1 healthy male volunteer single escalating dose study of the pharmacokinetics and pharmacodynamics of risdiplam (RG7916, RO7034067), a SMN2 splicing modifier von Sturm, Stefan, Günther, Andreas, Jaber, Birgit, Jordan, Paul, Al Kotbi, Nada, Parkar, Nikhat, Cleary, Yumi, Frances, Nicolas, Bergauer, Tobias, Heinig, Katja, Kletzl, Heidemarie, Marquet, Anne, Ratni, Hasane, Poirier, Agnès, Müller, Lutz, Czech, Christian, Khwaja, Omar

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Targeting Jak-Stat Signaling in Experimental Pulmonary Hypertension von Yerabolu, Dinesh, Weiss, Astrid, Kojonazarov, Baktybek, Boehm, Mario, Schlueter, Beate Christiane, Ruppert, Clemens, Günther, Andreas, Jonigk, Danny, Grimminger, Friedrich, Ghofrani, Hossein-Ardeschir, Seeger, Werner, Weissmann, Norbert, Schermuly, Ralph Theo

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Identification of a novel subset of alveolar type 2 cells enriched in PD-L1 and expanded following pneumonectomy von Ahmadvand, Negah, Khosravi, Farhad, Lingampally, Arun, Wasnick, Roxana, Vazquez-Armendariz, Ana Ivonne, Carraro, Gianni, Heiner, Monika, Rivetti, Stefano, Lv, Yuqing, Wilhelm, Jochen, Gunther, Andreas, Herold, Susanne, Al Alam, Denise, Chen, Chengshui, Minoo, Parviz, Zhang, Jin-San, Bellusci, Saverio

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Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells Is Required to Prevent Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease von Qi, Hui, Liu, Hang, Pullamsetti, Soni Savai, Günther, Stefan, Kuenne, Carsten, Atzberger, Ann, Sommer, Natascha, Hadzic, Stefan, Günther, Andreas, Weissmann, Norbert, Zhou, Yonggang, Yuan, Xuejun, Braun, Thomas

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FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury von Yuan, Tingting, Volckaert, Thomas, Redente, Elizabeth F., Hopkins, Seantel, Klinkhammer, Kylie, Wasnick, Roxana, Chao, Cho-Ming, Yuan, Jie, Zhang, Jin-San, Yao, Changfu, Majka, Susan, Stripp, Barry R., Günther, Andreas, Riches, David W.H., Bellusci, Saverio, Thannickal, Victor J., De Langhe, Stijn P.

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Addressing Today's Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRN... von Fowler, Stephen, Brink, Andreas, Cleary, Yumi, Günther, Andreas, Heinig, Katja, Husser, Christophe, Kletzl, Heidemarie, Kratochwil, Nicole, Mueller, Lutz, Savage, Mark, Stillhart, Cordula, Tuerck, Dietrich, Ullah, Mohammed, Umehara, Kenichi, Poirier, Agnès

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Effect of mild or moderate hepatic impairment on the pharmacokinetics of risdiplam von Kletzl, Heidemarie, Ajmi, Hassan, Antys, Izabela, Heinig, Katja, Jaber, Birgit, Marbury, Thomas C., Young, Annie, Günther, Andreas

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An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea von Yin, Wenguang, Liontos, Andreas, Koepke, Janine, Ghoul, Maroua, Mazzocchi, Luciana, Liu, Xinyuan, Lu, Chunyan, Wu, Haoyu, Fysikopoulos, Athanasios, Sountoulidis, Alexandros, Seeger, Werner, Ruppert, Clemens, Günther, Andreas, Stainier, Didier Y R, Samakovlis, Christos

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The role of tyrosine kinases in the pathogenesis of idiopathic pulmonary fibrosis von Grimminger, Friedrich, Günther, Andreas, Vancheri, Carlo

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Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis von MacKenzie, BreAnne, Korfei, Martina, Henneke, Ingrid, Sibinska, Zaneta, Tian, Xia, Hezel, Stefanie, Dilai, Salma, Wasnick, Roxana, Schneider, Beate, Wilhelm, Jochen, El Agha, Elie, Klepetko, Walter, Seeger, Werner, Schermuly, Ralph, Günther, Andreas, Bellusci, Saverio

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The Novel Dual Topoisomerase Inhibitor P8-D6 Shows Anti-myeloma Activity In Vitro and In Vivo von Klausz, Katja, Kellner, Christian, Gehlert, Carina Lynn, Krohn, Steffen, Wilcken, Hauke, Floerkemeier, Inken, Günther, Andreas, Bauerschlag, Dirk O, Clement, Bernd, Gramatzki, Martin, Peipp, Matthias

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Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation von Wettstein, Guillaume, Bellaye, Pierre‐Simon, Kolb, Martin, Hammann, Arlette, Crestani, Bruno, Soler, Paul, Marchal‐Somme, Joëlle, Hazoume, Adonis, Gauldie, Jack, Gunther, Andreas, Micheau, Olivier, Gleave, Martin, Camus, Philippe, Garrido, Carmen, Bonniaud, Philippe

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Opportunities and Risks of Resuscitation Attempts in Nursing Homes von Günther, Andreas, Schildmann, Jan, In der Schmitten, Jürgen, Schmid, Sybille, Weidlich-Wichmann, Uta, Fischer, Matthias

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