Tumor-targeted superantigens produce curative tumor immunity with induction of memory and demonstrated antigen spreading von Azulay, Meir, Shahar, Michal, Shany, Eitan, Elbaz, Eti, Lifshits, Sveta, Törngren, Marie, Friedmann, Adam, Kramer, Robert, Hedlund, Gunnar

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Synthesis and Biological Evaluation of New 1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for Treatment of Autoimmune Disorders:  Structure−Activity Relationship von Jönsson, Stig, Andersson, Gunnar, Fex, Tomas, Fristedt, Tomas, Hedlund, Gunnar, Jansson, Karl, Abramo, Lisbeth, Fritzson, Ingela, Pekarski, Olga, Runström, Anna, Sandin, Helena, Thuvesson, Ingela, Björk, Anders

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Phase I Dose Escalation, Pharmacokinetic and Pharmacodynamic Study of Naptumomab Estafenatox Alone in Patients With Advanced Cancer and With Docetaxel in Patients With Advanced Non... von Borghaei, Hossein, Alpaugh, Katherine, Hedlund, Gunnar, Forsberg, Göran, Langer, Corey, Rogatko, Andre, Hawkins, Robert, Dueland, Svein, Lassen, Ulrik, Cohen, Roger B

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The tumor targeted superantigen ABR-217620 selectively engages TRBV7-9 and exploits TCR-pMHC affinity mimicry in mediating T cell cytotoxicity von Hedlund, Gunnar, Eriksson, Helena, Sundstedt, Anette, Forsberg, Göran, Jakobsen, Bent K, Pumphrey, Nicholas, Rödström, Karin, Lindkvist-Petersson, Karin, Björk, Per

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The new orally active immunoregulator laquinimod (ABR-215062) effectively inhibits development and relapses of experimental autoimmune encephalomyelitis von Brunmark, Charlott, Runström, Anna, Ohlsson, Lennart, Sparre, Birgitta, Brodin, Thomas, Åström, Mikael, Hedlund, Gunnar

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A model of knowledge management and the N-form corporation von Hedlund, Gunnar

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Abstract 2712: Naptumomab Estafenatox induces T cell recognition, turning anti-PD-1 unresponsive "cold" tumors into "hot" responsive tumors von Azulay, Meir, Lifshits, Sveta, Fridman, Adam, Hedlund, Gunnar, Törngren, Marie, Shahar, Michal

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A Randomized Phase II/III Study of Naptumomab Estafenatox + IFNα versus IFNα in Renal Cell Carcinoma: Final Analysis with Baseline Biomarker Subgroup and Trend Analysis von Hawkins, Robert E, Gore, Martin, Shparyk, Yaroslav, Bondar, Vladimir, Gladkov, Oleg, Ganev, Tosho, Harza, Mihai, Polenkov, Serhii, Bondarenko, Igor, Karlov, Petr, Karyakin, Oleg, Khasanov, Rustem, Hedlund, Gunnar, Forsberg, Goran, Nordle, Örjan, Eisen, Timothy

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Combining tumor-targeted superantigens with interferon-alpha results in synergistic anti-tumor effects von Sundstedt, Anette, Celander, Mona, Hedlund, Gunnar

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Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-α versus IFN-... von Elkord, Eyad, Burt, Deborah J, Sundstedt, Anette, Nordle, Örjan, Hedlund, Gunnar, Hawkins, Robert E

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Naptumomab Estafenatox: Targeted Immunotherapy with a Novel Immunotoxin von Eisen, Tim, Hedlund, Gunnar, Forsberg, Göran, Hawkins, Robert

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Laquinimod (ABR-215062) suppresses the development of experimental autoimmune encephalomyelitis, modulates the Th1/Th2 balance and induces the Th3 cytokine TGF-β in Lewis rats von Yang, Jian-She, Xu, Ling-Yun, Xiao, Bao-Guo, Hedlund, Gunnar, Link, Hans

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Effects of Linomide on immune cells and cytokines inhibit autoimmune pathologies of the central and peripheral nervous system von Hedlund, Gunnar, Link, Hans, Zhu, Jie, Xiao, Bao-Guo

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Linomide abolishes leukocyte adhesion and extravascular recruitment induced by tumor necrosis factor α in vivo von Zhang, X W, Hedlund, G, Borgström, P, Arfors, K E, Thorlacius, H

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Abstract B17: Immunomodulation by tasquinimod: Combination with immunotherapy results in enhanced CD8 T cell responses and improved antitumor effects von Sundstedt, Anette, Olsson, Anders, Stenström, Martin, Celander, Mona, Törngren, Marie, Eriksson, Helena, Hedlund, Gunnar, Liberg, David, Leanderson, Tomas

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Monotherapeutically Nonactive CTLA-4 Blockade Results in Greatly Enhanced Antitumor Effects When Combined With Tumor-targeted Superantigens in a B16 Melanoma Model von SUNDSTEDT, Anette, CELANDER, Mona, ERIKSSON, Helena, TÖRNGREN, Marie, HEDLUND, Gunnar

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The hypermodern MNC-A heterarchy? von Hedlund, Gunnar

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Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse von Dahlén, E, Dawe, K, Ohlsson, L, Hedlund, G

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COMBINATIONS OF SUBSTITUTED BENZAMIDES AND 5-ASA AGENTS von HEDLUND, Gunnar, BJÖRK, Anders

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COMBINATIONS OF SUBSTITUTED BENZAMIDES AND 5-ASA AGENTS von HEDLUND, Gunnar, BJÖRK, Anders

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