MicroRNAs as biomarkers for CNS cancer and other disorders von De Smaele, Enrico, Ferretti, Elisabetta, Gulino, Alberto

Volltext

Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy von Miele, Evelina, Spinelli, Gian Paolo, Miele, Ermanno, Di Fabrizio, Enzo, Ferretti, Elisabetta, Tomao, Silverio, Gulino, Alberto

Volltext

Control of stem cells and cancer stem cells by Hedgehog signaling: Pharmacologic clues from pathway dissection von Coni, Sonia, Infante, Paola, Gulino, Alberto

Volltext

Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells von Valente, Sergio, Liu, Yiwei, Schnekenburger, Michael, Zwergel, Clemens, Cosconati, Sandro, Gros, Christina, Tardugno, Maria, Labella, Donatella, Florean, Cristina, Minden, Steven, Hashimoto, Hideharu, Chang, Yanqi, Zhang, Xing, Kirsch, Gilbert, Novellino, Ettore, Arimondo, Paola B, Miele, Evelina, Ferretti, Elisabetta, Gulino, Alberto, Diederich, Marc, Cheng, Xiaodong, Mai, Antonello

Volltext

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis von Infante, Paola, Faedda, Roberta, Bernardi, Flavia, Bufalieri, Francesca, Lospinoso Severini, Ludovica, Alfonsi, Romina, Mazzà, Daniela, Siler, Mariangela, Coni, Sonia, Po, Agnese, Petroni, Marialaura, Ferretti, Elisabetta, Mori, Mattia, De Smaele, Enrico, Canettieri, Gianluca, Capalbo, Carlo, Maroder, Marella, Screpanti, Isabella, Kool, Marcel, Pfister, Stefan M., Guardavaccaro, Daniele, Gulino, Alberto, Di Marcotullio, Lucia

Volltext

Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth von D’Amico, Davide, Antonucci, Laura, Di Magno, Laura, Coni, Sonia, Sdruscia, Giulia, Macone, Alberto, Miele, Evelina, Infante, Paola, Di Marcotullio, Lucia, De Smaele, Enrico, Ferretti, Elisabetta, Ciapponi, Laura, Giangaspero, Felice, Yates, John R., Agostinelli, Enzo, Cardinali, Beatrice, Screpanti, Isabella, Gulino, Alberto, Canettieri, Gianluca

Volltext

MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion von Sebastiani, Guido, Po, Agnese, Miele, Evelina, Ventriglia, Giuliana, Ceccarelli, Elena, Bugliani, Marco, Marselli, Lorella, Marchetti, Piero, Gulino, Alberto, Ferretti, Elisabetta, Dotta, Francesco

Volltext

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP von Bufalieri, Francesca, Infante, Paola, Bernardi, Flavia, Caimano, Miriam, Romania, Paolo, Moretti, Marta, Lospinoso Severini, Ludovica, Talbot, Julie, Melaiu, Ombretta, Tanori, Mirella, Di Magno, Laura, Bellavia, Diana, Capalbo, Carlo, Puget, Stéphanie, De Smaele, Enrico, Canettieri, Gianluca, Guardavaccaro, Daniele, Busino, Luca, Peschiaroli, Angelo, Pazzaglia, Simonetta, Giannini, Giuseppe, Melino, Gerry, Locatelli, Franco, Gulino, Alberto, Ayrault, Olivier, Fruci, Doriana, Di Marcotullio, Lucia

Volltext

MicroRNA profiling in human medulloblastoma von Ferretti, Elisabetta, De Smaele, Enrico, Po, Agnese, Di Marcotullio, Lucia, Tosi, Emanuele, Espinola, Maria Salome B., Di Rocco, Concezio, Riccardi, Riccardo, Giangaspero, Felice, Farcomeni, Alessio, Nofroni, Italo, Laneve, Pietro, Gioia, Ubaldo, Caffarelli, Elisa, Bozzoni, Irene, Screpanti, Isabella, Gulino, Alberto

Volltext

Proapoptotic Function of the Retinoblastoma Tumor Suppressor Protein von Ianari, Alessandra, Natale, Tiziana, Calo, Eliezer, Ferretti, Elisabetta, Alesse, Edoardo, Screpanti, Isabella, Haigis, Kevin, Gulino, Alberto, Lees, Jacqueline A.

Volltext

Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy von Coni, Sonia, Antonucci, Laura, D'Amico, Davide, Di Magno, Laura, Infante, Paola, De Smaele, Enrico, Giannini, Giuseppe, Di Marcotullio, Lucia, Screpanti, Isabella, Gulino, Alberto, Canettieri, Gianluca

Volltext

MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness von Evangelisti, Cristina, Florian, Maria Carolina, Massimi, Isabella, Dominici, Carlo, Giannini, Giuseppe, Galardi, Silvia, Buè, Maria Cristina, Massalini, Simone, McDowell, Heather P, Messi, Elio, Gulino, Alberto, Farace, Maria Giulia, Ciafrè, Silvia Anna

Volltext

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Depend... von La Regina, Giuseppe, Bai, Ruoli, Coluccia, Antonio, Famiglini, Valeria, Pelliccia, Sveva, Passacantilli, Sara, Mazzoccoli, Carmela, Ruggieri, Vitalba, Verrico, Annalisa, Miele, Andrea, Monti, Ludovica, Nalli, Marianna, Alfonsi, Romina, Di Marcotullio, Lucia, Gulino, Alberto, Ricci, Biancamaria, Soriani, Alessandra, Santoni, Angela, Caraglia, Michele, Porto, Stefania, Da Pozzo, Eleonora, Martini, Claudia, Brancale, Andrea, Marinelli, Luciana, Novellino, Ettore, Vultaggio, Stefania, Varasi, Mario, Mercurio, Ciro, Bigogno, Chiara, Dondio, Giulio, Hamel, Ernest, Lavia, Patrizia, Silvestri, Romano

Volltext

MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors von Petroni, Marialaura, Sardina, Francesca, Infante, Paola, Bartolazzi, Armando, Locatelli, Erica, Fabretti, Francesca, Di Giulio, Stefano, Capalbo, Carlo, Cardinali, Beatrice, Coppa, Anna, Tessitore, Alessandra, Colicchia, Valeria, Sahùn Roncero, Maria, Belardinilli, Francesca, Di Marcotullio, Lucia, Soddu, Silvia, Comes Franchini, Mauro, Petricci, Elena, Gulino, Alberto, Giannini, Giuseppe

Volltext

interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells von Laneve, Pietro, Di Marcotullio, Lucia, Gioia, Ubaldo, Fiori, Micol E, Ferretti, Elisabetta, Gulino, Alberto, Bozzoni, Irene, Caffarelli, Elisa

Volltext

Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL von Pelullo, Maria, Quaranta, Roberta, Talora, Claudio, Checquolo, Saula, Cialfi, Samantha, Felli, Maria Pia, te Kronnie, Geertruy, Borga, Chiara, Besharat, Zein Mersini, Palermo, Rocco, Di Marcotullio, Lucia, Capobianco, Anthony J, Gulino, Alberto, Screpanti, Isabella, Bellavia, Diana

Volltext

Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma von De Smaele, Enrico, Di Marcotullio, Lucia, Moretti, Marta, Pelloni, Marianna, Occhione, Maria Anna, Infante, Paola, Cucchi, Danilo, Greco, Azzura, Pietrosanti, Laura, Todorovic, Jelena, Coni, Sonia, Canettieri, Gianluca, Ferretti, Elisabetta, Bei, Roberto, Maroder, Marella, Screpanti, Isabella, Gulino, Alberto

Volltext

Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications von Jaffrain-Rea, Marie-Lise, Angelini, Mariolina, Gargano, Donatella, Tichomirowa, Maria A, Daly, Adrian F, Vanbellinghen, Jean-François, D'Innocenzo, Emanuela, Barlier, Anne, Giangaspero, Felice, Esposito, Vincenzo, Ventura, Luca, Arcella, Antonietta, Theodoropoulou, Marily, Naves, Luciana A, Fajardo, Carmen, Zacharieva, Sabina, Rohmer, Vincent, Brue, Thierry, Gulino, Alberto, Cantore, Giampaolo, Alesse, Edoardo, Beckers, Albert

Volltext

Differential regulation of E2F1 apoptotic target genes in response to DNA damage von Gulino, Alberto, Levrero, Massimo, Pediconi, Natalia, Ianari, Alessandra, Costanzo, Antonio, Belloni, Laura, Gallo, Rita, Cimino, Letizia, Porcellini, Antonio, Screpanti, Isabella, Balsano, Clara, Alesse, Edoardo

Volltext

Galectin-3 impairment of MYCN-dependent apoptosis-sensitive phenotype is antagonized by nutlin-3 in neuroblastoma cells von Veschi, Veronica, Petroni, Marialaura, Cardinali, Beatrice, Dominici, Carlo, Screpanti, Isabella, Frati, Luigi, Bartolazzi, Armando, Gulino, Alberto, Giannini, Giuseppe

Volltext