Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange von Guillard, Sandrine, Kolasinska-Zwierz, Paulina, Debreczeni, Judit, Breed, Jason, Zhang, Jing, Bery, Nicolas, Marwood, Rose, Tart, Jon, Overman, Ross, Stocki, Pawel, Mistry, Bina, Phillips, Christopher, Rabbitts, Terence, Jackson, Ronald, Minter, Ralph

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Engineering therapeutic proteins for cell entry: the natural approach von Guillard, Sandrine, Minter, Ralph R, Jackson, Ronald H

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Pharmacologic characterization of a potent inhibitor of class I phosphatidylinositide 3-kinases von RAYNAUD, Florence I, ECCLES, Suzanne, BJERKE, Lynn M, KELLAND, Lloyd, VALENTI, Melanie, PATTERSON, Lisa, GOWAN, Sharon, DE HAVEN BRANDON, Alexis, HAYAKAWA, Masahiko, KAIZAWA, Hiroyuki, KOIZUMI, Tomonubu, OHISHI, Takahide, CLARKE, Paul A, PATEL, Sonal, SAGHIR, Nahid, PARKER, Peter, WATERFIELD, Mike, WORKMAN, Paul, HAYES, Angela, NUTLEY, Bernard, ALIX, Sonia, HENLEY, Alan, DI-STEFANO, Francesca, AHMAD, Zahida, GUILLARD, Sandrine

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Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type von Rust, Steven, Guillard, Sandrine, Sachsenmeier, Kris, Hay, Carl, Davidson, Max, Karlsson, Anders, Karlsson, Roger, Brand, Erin, Lowne, David, Elvin, John, Flynn, Matt, Kurosawa, Gene, Hollingsworth, Robert, Jermutus, Lutz, Minter, Ralph

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Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants von Zubko, M.K, Guillard, S, Lydall, D

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Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human glioma von Guillard, Sandrine, Clarke, Paul A., te Poele, Robert, Mohri, Zahra, Bjerke, Lynn, Valenti, Melanie, Raynaud, Florence, Eccles, Suzanne A., Workman, Paul

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Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening von DiGiandomenico, Antonio, Warrener, Paul, Hamilton, Melissa, Guillard, Sandrine, Ravn, Peter, Minter, Ralph, Camara, Maria Margarita, Venkatraman, Vignesh, Macgill, Randall S, Lin, Jia, Wang, Qun, Keller, Ashley Elaine, Bonnell, Jessica C, Tomich, Mladen, Jermutus, Lutz, McCarthy, Michael P, Melnick, David A, Suzich, Joann A, Stover, C Kendall

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Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling von Sandercock, Alan M, Rust, Steven, Guillard, Sandrine, Sachsenmeier, Kris F, Holoweckyj, Nick, Hay, Carl, Flynn, Matt, Huang, Qihui, Yan, Kuan, Herpers, Bram, Price, Leo S, Soden, Jo, Freeth, Jim, Jermutus, Lutz, Hollingsworth, Robert, Minter, Ralph

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Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy von Williams, Geoffrey S, Mistry, Bina, Guillard, Sandrine, Ulrichsen, Jane Coates, Sandercock, Alan M, Wang, Jun, González-Muñoz, Andrea, Parmentier, Julie, Black, Chelsea, Soden, Jo, Freeth, Jim, Jovanović, Jelena, Leyland, Rebecca, Al-Lamki, Rafia S, Leishman, Andrew J, Rust, Steven J, Stewart, Ross, Jermutus, Lutz, Bradley, John R, Bedian, Vahe, Valge-Archer, Viia, Minter, Ralph, Wilkinson, Robert W

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A Genome-Wide Screen Identifies the Evolutionarily Conserved KEOPS Complex as a Telomere Regulator von Downey, Michael, Houlsworth, Rebecca, Maringele, Laura, Rollie, Adrienne, Brehme, Marc, Galicia, Sarah, Guillard, Sandrine, Partington, Melanie, Zubko, Mikhajlo K., Krogan, Nevan J., Emili, Andrew, Greenblatt, Jack F., Harrington, Lea, Lydall, David, Durocher, Daniel

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Drugging the PI3 kinome von Workman, Paul, Clarke, Paul A, Guillard, Sandrine, Raynaud, Florence I

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Abstract 4328: Phenotypic selection for identification of functional antibodies and development of high throughput screening assays von Hay, Carl, Rust, Steven, Sult, Erin, Clarke, Lori, Rosenthal, Kim, Guillard, Sandrine, Lowne, David, Flynn, Matt, Jermutus, Lutz, Minter, Ralph, Hollingsworth, Robert, Sachsenmeier, Kris

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Development of a Novel Ectonucleotidase Assay Suitable for High-Throughput Screening von Sachsenmeier, Kris F., Hay, Carl, Brand, Erin, Clarke, Lori, Rosenthal, Kim, Guillard, Sandrine, Rust, Steven, Minter, Ralph, Hollingsworth, Robert

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Abstract 4613: Identification of tumor necrosis factor receptor II as a regulatory T cell target for cancer immunotherapy using designed ankyrin repeat protein phenotypic selection... von Williams, Geoff, Anderton, Judith, Bedian, Vahe, Ulrichsen, Jane Coates, Gonzalez-Munoz, Andrea, Guillard, Sandrine, Harris, Olivia, Hair, James, Leishman, Andrew, Lewis, Arthur, Moissan, Jacques, Minter, Ralph, Mistry, Bina, Parmentier, Julie, Poon, Edmund, Popple, Amy, Rust, Steve, Sandercock, Alan, Stewart, Ross, Valge-Archer, Viia, Wilkinson, Robert W.

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Abstract 974: New target discovery for oncology utilizing phenotypic selection and primary NSCLC patient tumors von Holoweckyj, Nicholas M., Sandercock, Alan, Guillard, Sandrine, Rust, Steven, Hay, Carl, Brand, Erin, Meekin, John, Huang, Qihui, Sachsenmeier, Kris, Hollingsworth, Robert E., Minter, Ralph, Bowden, Emma

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MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants von Foster, Steven S., Zubko, Mikhajlo K., Guillard, Sandrine, Lydall, David

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Correction: Corrigendum: Drugging the PI3 kinome von Workman, Paul, Clarke, Paul A, Guillard, Sandrine, Raynaud, Florence I

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Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc 13-1 mutants von Zubko, Mikhajlo K, Guillard, Sandrine, Lydall, David

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Corrigendum: Drugging the PI3 kinome von Workman, Paul, Clarke, Paul A, Guillard, Sandrine, Raynaud, Florence I

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ANTI-PSEUDOMONAS PSL BINDING MOLECULES AND USES THEREOF von WARRENER, PAUL G, STOVER, CHARLES K, SELLMAN, BRET, TOMICH, MLADEN, RUST, STEVEN, GUILLARD, SANDRINE, MINTER, RALPH, DIGIANDOMENICO, ANTONIO

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