STING Agonists/Antagonists: Their Potential as Therapeutics and Future Developments von Guerini, Danilo

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Second generation S1P pathway modulators: Research strategies and clinical developments von Bigaud, Marc, Guerini, Danilo, Billich, Andreas, Bassilana, Frederic, Brinkmann, Volker

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Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors von Mullershausen, Florian, Seuwen, Klaus, Zecri, Frédéric, Cetin, Cihan, Billich, Andreas, Guerini, Danilo

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Small molecule induced STING degradation facilitated by the HECT ligase HERC4 von Mutlu, Merve, Schmidt, Isabel, Morrison, Andrew I., Goretzki, Benedikt, Freuler, Felix, Begue, Damien, Simic, Oliver, Pythoud, Nicolas, Ahrne, Erik, Kapps, Sandra, Roest, Susan, Bonenfant, Debora, Jeanpierre, Delphine, Tran, Thi-Thanh-Thao, Maher, Rob, An, Shaojian, Rietsch, Amandine, Nigsch, Florian, Hofmann, Andreas, Reece-Hoyes, John, Parker, Christian N., Guerini, Danilo

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Siponimod is a Functional Agonist for the S1P5 Receptor (P3.404) von Bigaud, Marc, Nuesslein-Hildesheim, Barbara, Tran, Thi-Thanh-Thao, Guerini, Danilo

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ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA von Greiner-Tollersrud, Ole Kristian, Krausz, Máté, Boehler, Vincent, Polyzou, Aikaterini, Seidl, Maximilian, Spahiu, Ambra, Abdullah, Zeinab, Andryka-Cegielski, Katarzyna, Dominick, Felix Immunuel, Huebscher, Katrin, Goschin, Andreas, Smulski, Cristian R., Trompouki, Eirini, Link, Regina, Ebersbach, Hilmar, Srinivas, Honnappa, Marchant, Martine, Sogkas, Georgios, Staab, Dieter, Vågbø, Cathrine, Guerini, Danilo, Baasch, Sebastian, Latz, Eicke, Hartmann, Gunther, Henneke, Philippe, Geiger, Roger, Peng, Xiao P., Grimbacher, Bodo, Bartok, Eva, Alseth, Ingrun, Warncke, Max, Proietti, Michele

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Investigating the molecular mechanisms through which FTY720‐P causes persistent S1P1 receptor internalization von Sykes, David A, Riddy, Darren M, Stamp, Craig, Bradley, Michelle E, McGuiness, Neil, Sattikar, Afrah, Guerini, Danilo, Rodrigues, Ines, Glaenzel, Albrecht, Dowling, Mark R, Mullershausen, Florian, Charlton, Steven J

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Phosphorylated FTY720 promotes astrocyte migration through sphingosine‐1‐phosphate receptors von Mullershausen, Florian, Craveiro, Luis M., Shin, Youngah, Cortes‐Cros, Marta, Bassilana, Frederic, Osinde, Maribel, Wishart, William L., Guerini, Danilo, Thallmair, Michaela, Schwab, Martin E., Sivasankaran, Rajeev, Seuwen, Klaus, Dev, Kumlesh K.

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Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically... von Albert, Rainer, Hinterding, Klaus, Brinkmann, Volker, Guerini, Danilo, Müller-Hartwieg, Constanze, Knecht, Helmut, Simeon, Corinne, Streiff, Markus, Wagner, Trixie, Welzenbach, Karl, Zécri, Frédéric, Zollinger, Markus, Cooke, Nigel, Francotte, Eric

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STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia von Morozzi, Giulio, Rothen, Julian, Toussaint, Gauthier, De Lange, Katrina, Westritschnig, Katrin, Doelemeyer, Arno, Ueberschlag, Vanessa Pitiot, Kahle, Peter, Lambert, Christian, Obrecht, Michael, Beckmann, Nicolau, Ritter, Veronique, Panesar, Moh, Stauffer, Daniela, Garnier, Isabelle, Mueller, Matthias, Guerini, Danilo, Keller, Caroline Gubser, Knehr, Judith, Roma, Guglielmo, Bidinosti, Michael, Brachat, Sophie, Morvan, Frederic, Fornaro, Mara

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Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation von Golks, Alexander, Tran, Thi-Thanh Thao, Goetschy, Jean Francois, Guerini, Danilo

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Reversible translocation of p115-RhoGEF by G12/13-coupled receptors von Meyer, Bruno H., Freuler, Felix, Guerini, Danilo, Siehler, Sandra

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Calcineurin Controls Inositol 1,4,5-Trisphosphate Type 1 Receptor Expression in Neurons von Genazzani, Armando A., Carafoli, Ernesto, Guerini, Danilo

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A Comparative Functional Analysis of Plasma Membrane Ca2+ Pump Isoforms in Intact Cells von Brini, Marisa, Coletto, Luisa, Pierobon, Nicola, Kraev, Natasha, Guerini, Danilo, Carafoli, Ernesto

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Calcineurin Controls the Transcription of Na+/Ca2+ Exchanger Isoforms in Developing Cerebellar Neurons von Li, Lei, Guerini, Danilo, Carafoli, Ernesto

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The O-linked N-acetylglucosamine modification in cellular signalling and the immune system. 'Protein modifications: beyond the usual suspects' review series von Golks, Alexander, Guerini, Danilo

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The O-linked N-acetylglucosamine modification in cellular signalling and the immune system von Golks, Alexander, Guerini, Danilo

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Design and Synthesis of Selective and Potent Orally Active S1P5 Agonists von Mattes, Henri, Dev, Kumlesh Kumar, Bouhelal, Rochdi, Barske, Carmen, Gasparini, Fabrizio, Guerini, Danilo, Mir, Anis Khusro, Orain, David, Osinde, Maribel, Picard, Anne, Dubois, Celine, Tasdelen, Engin, Haessig, Samuel

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TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis von Willemsen, Joschka, Neuhoff, Marie-Therese, Hoyler, Thomas, Noir, Emma, Tessier, Clemence, Sarret, Sophie, Thorsen, Tara N., Littlewood-Evans, Amanda, Zhang, Juan, Hasan, Maroof, Rush, James S., Guerini, Danilo, Siegel, Richard M.

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Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib von Rao, V. Koneti, Webster, Sharon, Dalm, Virgil A.S.H., Šedivá, Anna, van Hagen, P. Martin, Holland, Steven, Rosenzweig, Sergio D., Christ, Andreas D., Sloth, Birgitte, Cabanski, Maciej, Joshi, Aniket D., de Buck, Stefan, Doucet, Julie, Guerini, Danilo, Kalis, Christoph, Pylvaenaeinen, Ilona, Soldermann, Nicolas, Kashyap, Anuj, Uzel, Gulbu, Lenardo, Michael J., Patel, Dhavalkumar D., Lucas, Carrie L., Burkhart, Christoph

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