Pharmacology of Free Fatty Acid Receptors and Their Allosteric Modulators von Grundmann, Manuel, Bender, Eckhard, Schamberger, Jens, Eitner, Frank

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Lack of beta-arrestin signaling in the absence of active G proteins von Grundmann, Manuel, Merten, Nicole, Malfacini, Davide, Inoue, Asuka, Preis, Philip, Simon, Katharina, Rüttiger, Nelly, Ziegler, Nicole, Benkel, Tobias, Schmitt, Nina Katharina, Ishida, Satoru, Müller, Ines, Reher, Raphael, Kawakami, Kouki, Inoue, Ayumi, Rick, Ulrike, Kühl, Toni, Imhof, Diana, Aoki, Junken, König, Gabriele M., Hoffmann, Carsten, Gomeza, Jesus, Wess, Jürgen, Kostenis, Evi

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Direct Blood Pressure-Independent Anti-Fibrotic Effects by the Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone in Progressive Models of Kidney Fibrosis von Droebner, Karoline, Pavkovic, Mira, Grundmann, Manuel, Hartmann, Elke, Goea, Laura, Nordlohne, Johannes, Klar, Jürgen, Eitner, Frank, Kolkhof, Peter

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Applying label-free dynamic mass redistribution technology to frame signaling of G protein–coupled receptors noninvasively in living cells von Schröder, Ralf, Schmidt, Johannes, Blättermann, Stefanie, Peters, Lucas, Janssen, Nicole, Grundmann, Manuel, Seemann, Wiebke, Kaufel, Dorina, Merten, Nicole, Drewke, Christel, Gomeza, Jesus, Milligan, Graeme, Mohr, Klaus, Kostenis, Evi

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A flow cytometry approach reveals heterogeneity in conventional subsets of murine renal mononuclear phagocytes von Nordlohne, Johannes, Hulsmann, Ilona, Schwafertz, Svenja, Zgrajek, Jasmin, Grundmann, Manuel, von Vietinghoff, Sibylle, Eitner, Frank, Becker, Michael S.

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Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs von Hudson, Brian D., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Kostenis, Evi, Adams, David R., Ulven, Trond, Milligan, Graeme

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cNMP-AMs mimic and dissect bacterial nucleotidyl cyclase toxin effects von Beckert, Ulrike, Grundmann, Manuel, Wolter, Sabine, Schwede, Frank, Rehmann, Holger, Kaever, Volkhard, Kostenis, Evi, Seifert, Roland

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Reevaluation of Fatty Acid Receptor 1 as a Drug Target for the Stimulation of Insulin Secretion in Humans von WAGNER, Robert, KAISER, Gabriele, FRITSCHE, Andreas, HÄRING, Hans-Ulrich, ULLRICH, Susanne, GERST, Felicia, CHRISTIANSEN, Elisabeth, DUE-HANSEN, Maria E, GRUNDMANN, Manuel, MACHICAO, Fausto, PETER, Andreas, KOSTENIS, Evi, ULVEN, Trond

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The effects of CD148 Q276P/R326Q polymorphisms in A431D epidermoid cancer cell proliferation and epidermal growth factor receptor signaling von He, Lilly, Takahashi, Keiko, Pasic, Lejla, Narui, Chikage, Ellinger, Philipp, Grundmann, Manuel, Takahashi, Takamune

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The molecular mechanism by which saturated lysophosphatidylcholine attenuates the metastatic capacity of melanoma cells von Ross, Thomas, Jakubzig, Bastian, Grundmann, Manuel, Massing, Ulrich, Kostenis, Evi, Schlesinger, Martin, Bendas, Gerd

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Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes von Christiansen, Elisabeth, Hansen, Steffen V. F, Urban, Christian, Hudson, Brian D, Wargent, Edward T, Grundmann, Manuel, Jenkins, Laura, Zaibi, Mohamed, Stocker, Claire J, Ullrich, Susanne, Kostenis, Evi, Kassack, Matthias U, Milligan, Graeme, Cawthorne, Michael A, Ulven, Trond

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Temporal Bias: Time-Encoded Dynamic GPCR Signaling von Grundmann, Manuel, Kostenis, Evi

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Label‐Free Dynamic Mass Redistribution and Bio‐Impedance Methods for Drug Discovery von Grundmann, Manuel

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Label-Free Whole Cell Biosensing for High-Throughput Discovery of Activators and Inhibitors Targeting G Protein-Activated Inwardly Rectifying Potassium Channels von Krebs, Katrin M, Pfeil, Eva M, Simon, Katharina, Grundmann, Manuel, Häberlein, Felix, Bautista-Aguilera, Oscar M, Gütschow, Michael, Weaver, C. David, Fleischmann, Bernd K, Kostenis, Evi

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Single-Cell Resolution Drug Effects on RAAS Blockade in ZSF1 Rat Diabetic Kidney Disease: FR-OR36 von Balzer, Michael S., Zhou, Jianfu, Abedini, Amin, Ma, Ziyuan, Grundmann, Manuel, Pavkovic, Mira, Susztak, Katalin

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Label-Free Biosensor Assays in GPCR Screening von Grundmann, Manuel, Kostenis, Evi

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Allosteric targeting of the FFA2 receptor (GPR43) restores responsiveness of desensitized human neutrophils von Frei, Robert, Nordlohne, Johannes, Hüser, Ulrike, Hild, Seda, Schmidt, Johannes, Eitner, Frank, Grundmann, Manuel

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Selective Orthosteric Free Fatty Acid Receptor 2 (FFA2) Agonists von Schmidt, Johannes, Smith, Nicola J., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Hudson, Brian D., Ward, Richard J., Drewke, Christel, Milligan, Graeme, Kostenis, Evi, Ulven, Trond

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The Novel Nonsteroidal and Selective Mineralocorticoid Receptor Antagonist Finerenone Differentiates from SGLT2 Inhibitor Empagliflozin by Anti-Fibrotic Effects in a Progressive Mo... von Droebner, Karoline, Pavkovic, Mira, Grundmann, Manuel, Hartmann, Elke, Goea, Laura, Nordlohne, Johannes, Eitner, Frank, Kolkhof, Peter

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Genetic Ablation of CD148 Increases Renal Macrophage Inflammation and Fibrosis in Ureteral Obstructed Kidney: PO0654 von Otsuka, Tadashi, Takahashi, Keiko, Narui, Chikage, Harris, Raymond C., Grundmann, Manuel, Takahashi, Takamune, Pasic, Lejla

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