Antibody Responses after a Single Dose of SARS-CoV-2 mRNA Vaccine von Bradley, Todd, Grundberg, Elin, Selvarangan, Rangaraj, LeMaster, Cas, Fraley, Elizabeth, Banerjee, Dithi, Belden, Bradley, Louiselle, Daniel, Nolte, Nick, Biswell, Rebecca, Pastinen, Tomi, Myers, Angela, Schuster, Jennifer

Volltext

Cross-reactive antibodies elicited to conserved epitopes on SARS-CoV-2 spike protein after infection and vaccination von Geanes, Eric S., LeMaster, Cas, Fraley, Elizabeth R., Khanal, Santosh, McLennan, Rebecca, Grundberg, Elin, Selvarangan, Rangaraj, Bradley, Todd

Volltext

Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range von Winkley, Konner, Banerjee, Dithi, Bradley, Todd, Koseva, Boryana, Cheung, Warren A., Selvarangan, Rangaraj, Pastinen, Tomi, Grundberg, Elin

Volltext

Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals von Fraley, Elizabeth, LeMaster, Cas, Geanes, Eric, Banerjee, Dithi, Khanal, Santosh, Grundberg, Elin, Selvarangan, Rangaraj, Bradley, Todd

Volltext

Capturing functional epigenomes for insight into metabolic diseases von Allum, Fiona, Grundberg, Elin

Volltext

Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto–Kakizaki rats improves glucose homeostasis through enhanced FXR signalling von Péan, Noémie, Le Lay, Aurelie, Brial, Francois, Wasserscheid, Jessica, Rouch, Claude, Vincent, Mylène, Myridakis, Antonis, Hedjazi, Lyamine, Dumas, Marc-Emmanuel, Grundberg, Elin, Lathrop, Mark, Magnan, Christophe, Dewar, Ken, Gauguier, Dominique

Volltext

Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population von Bell, Jordana T, Tsai, Pei-Chien, Yang, Tsun-Po, Pidsley, Ruth, Nisbet, James, Glass, Daniel, Mangino, Massimo, Zhai, Guangju, Zhang, Feng, Valdes, Ana, Shin, So-Youn, Dempster, Emma L, Murray, Robin M, Grundberg, Elin, Hedman, Asa K, Nica, Alexandra, Small, Kerrin S, Dermitzakis, Emmanouil T, McCarthy, Mark I, Mill, Jonathan, Spector, Tim D, Deloukas, Panos

Volltext

Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types von Vijay, Jinchu, Gauthier, Marie-Frédérique, Biswell, Rebecca L., Louiselle, Daniel A., Johnston, Jeffrey J., Cheung, Warren A., Belden, Bradley, Pramatarova, Albena, Biertho, Laurent, Gibson, Margaret, Simon, Marie-Michelle, Djambazian, Haig, Staffa, Alfredo, Bourque, Guillaume, Laitinen, Anita, Nystedt, Johanna, Vohl, Marie-Claude, Fraser, Jason D., Pastinen, Tomi, Tchernof, André, Grundberg, Elin

Volltext

ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development von Varberg, Kaela M., Iqbal, Khursheed, Muto, Masanaga, Simon, Mikaela E., Scott, Regan L., Kozai, Keisuke, Choudhury, Ruhul H., Aplin, John D., Biswell, Rebecca, Gibson, Margaret, Okae, Hiroaki, Arima, Takahiro, Vivian, Jay L., Grundberg, Elin, Soares, Michael J.

Volltext

An epigenome-wide association study of total serum immunoglobulin E concentration von Liang, Liming, Willis-Owen, Saffron A. G., Laprise, Catherine, Wong, Kenny C. C., Davies, Gwyneth A., Hudson, Thomas J., Binia, Aristea, Hopkin, Julian M., Yang, Ivana V., Grundberg, Elin, Busche, Stephan, Hudson, Marie, Rönnblom, Lars, Pastinen, Tomi M., Schwartz, David A., Lathrop, G. Mark, Moffatt, Miriam F., Cookson, William O. C. M.

Volltext

Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape von Varberg, Kaela M., Dominguez, Esteban M., Koseva, Boryana, Varberg, Joseph M., McNally, Ross P., Moreno-Irusta, Ayelen, Wesley, Emily R., Iqbal, Khursheed, Cheung, Warren A., Schwendinger-Schreck, Carl, Smail, Craig, Okae, Hiroaki, Arima, Takahiro, Lydic, Michael, Holoch, Kristin, Marsh, Courtney, Soares, Michael J., Grundberg, Elin

Volltext

Complex trait associations in rare diseases and impacts on Mendelian variant interpretation von Smail, Craig, Ge, Bing, Keever-Keigher, Marissa R., Schwendinger-Schreck, Carl, Cheung, Warren A., Johnston, Jeffrey J., Barrett, Cassandra, Feldman, Keith, Cohen, Ana S. A., Farrow, Emily G., Thiffault, Isabelle, Grundberg, Elin, Pastinen, Tomi

Volltext

Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation von Busche, Stephan, Shao, Xiaojian, Caron, Maxime, Kwan, Tony, Allum, Fiona, Cheung, Warren A, Ge, Bing, Westfall, Susan, Simon, Marie-Michelle, Barrett, Amy, Bell, Jordana T, McCarthy, Mark I, Deloukas, Panos, Blanchette, Mathieu, Bourque, Guillaume, Spector, Timothy D, Lathrop, Mark, Pastinen, Tomi, Grundberg, Elin

Volltext

Intersection of regulatory pathways controlling hemostasis and hemochorial placentation von Muto, Masanaga, Chakraborty, Damayanti, Varberg, Kaela M., Moreno-Irusta, Ayelen, Iqbal, Khursheed, Scott, Regan L., McNally, Ross P., Choudhury, Ruhul H., Aplin, John D., Okae, Hiroaki, Arima, Takahiro, Matsumoto, Shoma, Ema, Masatsugu, Mast, Alan E., Grundberg, Elin, Soares, Michael J.

Volltext

Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements von Allum, Fiona, Hedman, Åsa K., Shao, Xiaojian, Cheung, Warren A., Vijay, Jinchu, Guénard, Frédéric, Kwan, Tony, Simon, Marie-Michelle, Ge, Bing, Moura, Cristiano, Boulier, Elodie, Rönnblom, Lars, Bernatsky, Sasha, Lathrop, Mark, McCarthy, Mark I., Deloukas, Panos, Tchernof, André, Pastinen, Tomi, Vohl, Marie-Claude, Grundberg, Elin

Volltext

Direct haplotype-resolved 5-base HiFi sequencing for genome-wide profiling of hypermethylation outliers in a rare disease cohort von Cheung, Warren A., Johnson, Adam F., Rowell, William J., Farrow, Emily, Hall, Richard, Cohen, Ana S. A., Means, John C., Zion, Tricia N., Portik, Daniel M., Saunders, Christopher T., Koseva, Boryana, Bi, Chengpeng, Truong, Tina K., Schwendinger-Schreck, Carl, Yoo, Byunggil, Johnston, Jeffrey J., Gibson, Margaret, Evrony, Gilad, Rizzo, William B., Thiffault, Isabelle, Younger, Scott T., Curran, Tom, Wenger, Aaron M., Grundberg, Elin, Pastinen, Tomi

Volltext

A comparison of the whole genome approach of MeDIP-seq to the targeted approach of the Infinium HumanMethylation450 BeadChip(®) for methylome profiling von Clark, Christine, Palta, Priit, Joyce, Christopher J, Scott, Carol, Grundberg, Elin, Deloukas, Panos, Palotie, Aarno, Coffey, Alison J

Volltext

Genomic insights into pediatric intestinal inflammatory and eosinophilic disorders using single-cell RNA-sequencing von Keever-Keigher, Marissa R, Harvey, Lisa, Williams, Veronica, Vyhlidal, Carrie A, Ahmed, Atif A, Johnston, Jeffery J, Louiselle, Daniel A, Grundberg, Elin, Pastinen, Tomi, Friesen, Craig A, Chevalier, Rachel, Smail, Craig, Shakhnovich, Valentina

Volltext

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure von Paternoster, Lavinia, Lorentzon, Mattias, Lehtimäki, Terho, Eriksson, Joel, Kähönen, Mika, Raitakari, Olli, Laaksonen, Marika, Sievänen, Harri, Viikari, Jorma, Lyytikäinen, Leo-Pekka, Mellström, Dan, Karlsson, Magnus, Ljunggren, Osten, Grundberg, Elin, Kemp, John P, Sayers, Adrian, Nethander, Maria, Evans, David M, Vandenput, Liesbeth, Tobias, Jon H, Ohlsson, Claes

Volltext

Higher chylomicron remnants and LDL particle numbers associate with CD36 SNPs and DNA methylation sites that reduce CD36[S] von Love-Gregory, Latisha, Kraja, Aldi T., Allum, Fiona, Aslibekyan, Stella, Hedman, Åsa K., Duan, Yanan, Borecki, Ingrid B., Arnett, Donna K., McCarthy, Mark I., Deloukas, Panos, Ordovas, Jose M., Hopkins, Paul N., Grundberg, Elin, Abumrad, Nada A.

Volltext