The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease von Ryskamp, Daniel, Wu, Jun, Geva, Michal, Kusko, Rebecca, Grossman, Iris, Hayden, Michael, Bezprozvanny, Ilya

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A Secreted Disulfide Catalyst Controls Extracellular Matrix Composition and Function von Ilani, Tal, Alon, Assaf, Grossman, Iris, Horowitz, Ben, Kartvetishvily, Elena, Cohen, Sidney R., Fass, Deborah

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cis‐Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures von Javitt, Gabriel, Grossman‐Haham, Iris, Alon, Assaf, Resnick, Efrat, Mutsafi, Yael, Ilani, Tal, Fass, Deborah

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Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor von Kaye, Joel, Piryatinsky, Victor, Birnberg, Tal, Hingaly, Tal, Raymond, Emanuel, Kashi, Rina, Amit-Romach, Einat, Caballero, Ignacio S., Towfic, Fadi, Ator, Mark A., Rubinstein, Efrat, Laifenfeld, Daphna, Orbach, Aric, Shinar, Doron, Marantz, Yael, Grossman, Iris, Knappertz, Volker, Hayden, Michael R., Laufer, Ralph

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Slow domain reconfiguration causes power-law kinetics in a two-state enzyme von Grossman-Haham, Iris, Rosenblum, Gabriel, Namani, Trishool, Hofmann, Hagen

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Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration von Ramaswami, Gokul, Yuva-Aydemir, Yeliz, Akerberg, Brynn, Matthews, Bryan, Williams, Jenna, Golczer, Gabriel, Huang, Jiaqi, Al Abdullatif, Ali, Huh, Dann, Burkly, Linda C., Engle, Sandra J., Grossman, Iris, Sehgal, Alfica, Sigova, Alla A., Fremeau, Robert T., Liu, Yuting, Bumcrot, David

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Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson's disease: a pharmacogenetic study von Masellis, Mario, Collinson, Shannon, Freeman, Natalie, Tampakeras, Maria, Levy, Joseph, Tchelet, Amir, Eyal, Eli, Berkovich, Elijahu, Eliaz, Rom E, Abler, Victor, Grossman, Iris, Fitzer-Attas, Cheryl, Tiwari, Arun, Hayden, Michael R, Kennedy, James L, Lang, Anthony E, Knight, Jo

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Author Correction: Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration von Ramaswami, Gokul, Yuva-Aydemir, Yeliz, Akerberg, Brynn, Matthews, Bryan, Williams, Jenna, Golczer, Gabriel, Huang, Jiaqi, Al Abdullatif, Ali, Huh, Dann, Burkly, Linda C., Engle, Sandra J., Grossman, Iris, Sehgal, Alfica, Sigova, Alla A., Fremeau, Robert T., Liu, Yuting, Bumcrot, David

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Perturbed N-glycosylation of Halobacterium salinarum archaellum filaments leads to filament bundling and compromised cell motility von Sofer, Shahar, Vershinin, Zlata, Mashni, Leen, Zalk, Ran, Shahar, Anat, Eichler, Jerry, Grossman-Haham, Iris

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Emulated Clinical Trials from Longitudinal Real-World Data Efficiently Identify Candidates for Neurological Disease Modification: Examples from Parkinson's Disease von Laifenfeld, Daphna, Yanover, Chen, Ozery-Flato, Michal, Shaham, Oded, Rosen-Zvi, Michal, Lev, Nirit, Goldschmidt, Yaara, Grossman, Iris

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The dynamic disulphide relay of quiescin sulphydryl oxidase von Alon, Assaf, Grossman, Iris, Gat, Yair, Kodali, Vamsi K., DiMaio, Frank, Mehlman, Tevie, Haran, Gilad, Baker, David, Thorpe, Colin, Fass, Deborah

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Characterizing patient compliance over six months in remote digital trials of Parkinson's and Huntington disease von Cohen, Shani, Waks, Zeev, Elm, Jordan J, Gordon, Mark Forrest, Grachev, Igor D, Navon-Perry, Leehee, Fine, Shai, Grossman, Iris, Papapetropoulos, Spyros, Savola, Juha-Matti

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Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse von Kusko, Rebecca, Dreymann, Jennifer, Ross, Jermaine, Cha, Yoonjeong, Escalante-Chong, Renan, Garcia-Miralles, Marta, Tan, Liang Juin, Burczynski, Michael E, Zeskind, Ben, Laifenfeld, Daphna, Pouladi, Mahmoud, Geva, Michal, Grossman, Iris, Hayden, Michael R

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Single-molecule spectroscopy exposes hidden states in an enzymatic electron relay von Grossman, Iris, Yuval Aviram, Haim, Armony, Gad, Horovitz, Amnon, Hofmann, Hagen, Haran, Gilad, Fass, Deborah

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Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating von Grossman-Haham, Iris, Coudray, Nicolas, Yu, Zanlin, Wang, Feng, Zhang, Nan, Bhabha, Gira, Vale, Ronald D.

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Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings von Schwartz, Brian E., Rajagopal, Vaishnavi, Smith, Cynthia, Cohick, Evan, Whissell, Gavin, Gamboa, Mario, Pai, Rutuja, Sigova, Alla, Grossman, Iris, Bumcrot, David, Sasidharan, Kavitha, Romeo, Stefano, Sehgal, Alfica, Pingitore, Piero

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Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis von Need, Anna C, Keefe, Richard SE, Ge, Dongliang, Grossman, Iris, Dickson, Sam, McEvoy, Joseph P, Goldstein, David B

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A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis von Ross, Colin J, Towfic, Fadi, Shankar, Jyoti, Laifenfeld, Daphna, Thoma, Mathis, Davis, Matthew, Weiner, Brian, Kusko, Rebecca, Zeskind, Ben, Knappertz, Volker, Grossman, Iris, Hayden, Michael R

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Biobanking in Israel 2016-17; expressed perceptions versus real life enrollment von Koren, Gideon, Beller, Daniella, Laifenfeld, Daphna, Grossman, Iris, Shalev, Varda

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Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models von Feldman, Tal, Grossman-Haham, Iris, Elkis, Yoav, Vilela, Patrick, Moskovits, Neta, Barshack, Iris, Salame, Tomer M, Fass, Deborah, Ilani, Tal

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