Epigenetics: a molecular link between environmental factors and type 2 diabetes von Ling, Charlotte, Groop, Leif

Volltext

Genetics of diabetes – Are we missing the genes or the disease? von Groop, Leif, Pociot, Flemming

Volltext

Genetics of type 2 diabetes-pitfalls and possibilities von Prasad, Rashmi B, Groop, Leif

Volltext

The (in)famous GWAS P-value threshold revisited and updated for low-frequency variants von Fadista, João, Manning, Alisa K, Florez, Jose C, Groop, Leif

Volltext

Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis von Skyler, Jay S, Bakris, George L, Bonifacio, Ezio, Darsow, Tamara, Eckel, Robert H, Groop, Leif, Groop, Per-Henrik, Handelsman, Yehuda, Insel, Richard A, Mathieu, Chantal, McElvaine, Allison T, Palmer, Jerry P, Pugliese, Alberto, Schatz, Desmond A, Sosenko, Jay M, Wilding, John P H, Ratner, Robert E

Volltext

The many faces of diabetes: a disease with increasing heterogeneity von Tuomi, Tiinamaija, MD, Santoro, Nicola, MD, Caprio, Sonia, Prof, Cai, Mengyin, MD, Weng, Jianping, Prof, Groop, Leif, Prof

Volltext

LoFtool: a gene intolerance score based on loss-of-function variants in 60 706 individuals von Fadista, João, Oskolkov, Nikolay, Hansson, Ola, Groop, Leif

Volltext

Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women von Pan, An, Schernhammer, Eva S, Sun, Qi, Hu, Frank B

Volltext

100 YEARS OF INSULIN: Towards improved precision and a new classification of diabetes mellitus von Ahlqvist, Emma, Prasad, Rashmi B, Groop, Leif

Volltext

Prevalence and risk factors of gestational diabetes in Punjab, North India: results from a population screening program von Arora, Geeti P, Thaman, Richa G, Prasad, Rashmi B, Almgren, Peter, Brøns, Charlotte, Groop, Leif C, Vaag, Allan A

Volltext

A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes von Taira, Makiko, Imamura, Minako, Takahashi, Atsushi, Kamatani, Yoichiro, Yamauchi, Toshimasa, Araki, Shin-Ichi, Tanaka, Nobue, van Zuydam, Natalie R, Ahlqvist, Emma, Toyoda, Masao, Umezono, Tomoya, Kawai, Koichi, Imanishi, Masahito, Watada, Hirotaka, Suzuki, Daisuke, Maegawa, Hiroshi, Babazono, Tetsuya, Kaku, Kohei, Kawamori, Ryuzo, Groop, Leif C, McCarthy, Mark I, Kadowaki, Takashi, Maeda, Shiro

Volltext

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes von Jaiswal, Siddhartha, Fontanillas, Pierre, Flannick, Jason, Manning, Alisa, Grauman, Peter V, Mar, Brenton G, Lindsley, R. Coleman, Mermel, Craig H, Burtt, Noel, Chavez, Alejandro, Higgins, John M, Moltchanov, Vladislav, Kuo, Frank C, Kluk, Michael J, Henderson, Brian, Kinnunen, Leena, Koistinen, Heikki A, Ladenvall, Claes, Getz, Gad, Correa, Adolfo, Banahan, Benjamin F, Gabriel, Stacey, Kathiresan, Sekar, Stringham, Heather M, McCarthy, Mark I, Boehnke, Michael, Tuomilehto, Jaakko, Haiman, Christopher, Groop, Leif, Atzmon, Gil, Wilson, James G, Neuberg, Donna, Altshuler, David, Ebert, Benjamin L

Volltext

Early metabolic markers identify potential targets for the prevention of type 2 diabetes von Peddinti, Gopal, Cobb, Jeff, Yengo, Loic, Froguel, Philippe, Kravić, Jasmina, Balkau, Beverley, Tuomi, Tiinamaija, Aittokallio, Tero, Groop, Leif

Volltext

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes von Bacos, Karl, Gillberg, Linn, Volkov, Petr, Olsson, Anders H, Hansen, Torben, Pedersen, Oluf, Gjesing, Anette Prior, Eiberg, Hans, Tuomi, Tiinamaija, Almgren, Peter, Groop, Leif, Eliasson, Lena, Vaag, Allan, Dayeh, Tasnim, Ling, Charlotte

Volltext

Genetics of type 2 diabetes von Ahlqvist, Emma, Ahluwalia, Tarunveer Singh, Groop, Leif

Volltext

Reappraisal of metformin efficacy in the treatment of type 2 diabetes: a meta-analysis of randomised controlled trials von Boussageon, Rémy, Supper, Irène, Bejan-Angoulvant, Theodora, Kellou, Nadir, Cucherat, Michel, Boissel, Jean-Pierre, Kassai, Behrouz, Moreau, Alain, Gueyffier, François, Cornu, Catherine

Volltext

Common Single Nucleotide Polymorphisms in TCF7L2 Are Reproducibly Associated With Type 2 Diabetes and Reduce the Insulin Response to Glucose in Nondiabetic Individuals von SAXENA, Richa, GIANNINY, Lauren, LINDBLAD, Ulf, DALY, Mark J, TUOMI, Tiinamaija, HIRSCHHORN, Joel N, ARDLIE, Kristin G, GROOP, Leif C, ALTSHULER, David, BURTT, Noël P, LYSSENKO, Valeriya, GIUDUCCI, Candace, SJÖGREN, Marketa, FLOREZ, Jose C, ALMGREN, Peter, ISOMAA, Bo, ORHO-MELANDER, Marju

Volltext

A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue von Rönn, Tina, Volkov, Petr, Davegårdh, Cajsa, Dayeh, Tasnim, Hall, Elin, Olsson, Anders H, Nilsson, Emma, Tornberg, Asa, Dekker Nitert, Marloes, Eriksson, Karl-Fredrik, Jones, Helena A, Groop, Leif, Ling, Charlotte

Volltext

Cohort profile: Epigenetics in Pregnancy (EPIPREG) - population-based sample of European and South Asian pregnant women with epigenome-wide DNA methylation (850k) in peripheral blo... von Fragoso-Bargas, Nicolas, Opsahl, Julia O., Kiryushchenko, Nadezhda, Bottcher, Yvonne, Lee-Odegard, Sindre, Qvigstad, Elisabeth, Richardsen, Kare Ronn, Waage, Christin W., Sletner, Line, Jenum, Anne Karen, Prasad, Rashmi B., Groop, Leif C., Moen, Gunn-Helen, Birkeland, Kare, Sommer, Christine

Volltext

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism von Fadista, João, Vikman, Petter, Laakso, Emilia Ottosson, Mollet, Inês Guerra, Esguerra, Jonathan Lou, Taneera, Jalal, Storm, Petter, Osmark, Peter, Ladenvall, Claes, Prasad, Rashmi B., Hansson, Karin B., Finotello, Francesca, Uvebrant, Kristina, Ofori, Jones K., Di Camillo, Barbara, Krus, Ulrika, Cilio, Corrado M., Hansson, Ola, Eliasson, Lena, Rosengren, Anders H., Renström, Erik, Wollheim, Claes B., Groop, Leif

Volltext