Small But Increasingly Mighty: Latest Advances in AAV Vector Research, Design, and Evolution von Grimm, Dirk, Büning, Hildegard

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When size matters: A novel compact Cas12a variant for in vivo genome editing von Bubeck, Felix, Grimm, Dirk

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Adeno-Associated Viruses (AAV) and Host Immunity - A Race Between the Hare and the Hedgehog von Rapti, Kleopatra, Grimm, Dirk

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E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal—Tailored Acceleration of AAV Evolution von Grimm, Dirk, Zolotukhin, Sergei

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The dose can make the poison: lessons learned from adverse in vivo toxicities caused by RNAi overexpression von Grimm, Dirk

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CRISPR genome engineering and viral gene delivery: A case of mutual attraction von Schmidt, Florian, Grimm, Dirk

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Next-generation AAV vectors for clinical use: an ever-accelerating race von Weinmann, Jonas, Grimm, Dirk

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Methane formation driven by reactive oxygen species across all living organisms von Ernst, Leonard, Steinfeld, Benedikt, Barayeu, Uladzimir, Klintzsch, Thomas, Kurth, Markus, Grimm, Dirk, Dick, Tobias P., Rebelein, Johannes G., Bischofs, Ilka B., Keppler, Frank

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Fantastic AAV Gene Therapy Vectors and How to Find Them—Random Diversification, Rational Design and Machine Learning von Becker, Jonas, Fakhiri, Julia, Grimm, Dirk

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All for One, One for All: New Combinatorial RNAi Therapies Combat Hepatitis C Virus Evolution von Grimm, Dirk

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Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants von Weinmann, Jonas, Weis, Sabrina, Sippel, Josefine, Tulalamba, Warut, Remes, Anca, El Andari, Jihad, Herrmann, Anne-Kathrin, Pham, Quang H., Borowski, Christopher, Hille, Susanne, Schönberger, Tanja, Frey, Norbert, Lenter, Martin, VandenDriessche, Thierry, Müller, Oliver J., Chuah, Marinee K., Lamla, Thorsten, Grimm, Dirk

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A breath of fresh air: targeted non-viral in vivo gene correction in the mammalian lung von Liu, Jixin, Grimm, Dirk

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Cell-specific CRISPR-Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins von Hoffmann, Mareike D, Aschenbrenner, Sabine, Grosse, Stefanie, Rapti, Kleopatra, Domenger, Claire, Fakhiri, Julia, Mastel, Manuel, Börner, Kathleen, Eils, Roland, Grimm, Dirk, Niopek, Dominik

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Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration von Malato, Yann, Naqvi, Syed, Schürmann, Nina, Ng, Raymond, Wang, Bruce, Zape, Joan, Kay, Mark A, Grimm, Dirk, Willenbring, Holger

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Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice von Michler, Thomas, Kosinska, Anna D., Festag, Julia, Bunse, Till, Su, Jinpeng, Ringelhan, Marc, Imhof, Hortenzia, Grimm, Dirk, Steiger, Katja, Mogler, Carolin, Heikenwalder, Mathias, Michel, Marie-Louise, Guzman, Carlos A., Milstein, Stuart, Sepp-Lorenzino, Laura, Knolle, Percy, Protzer, Ulrike

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Membrane-destabilizing ionizable phospholipids: Novel components for organ-selective mRNA delivery and CRISPR–Cas gene editing von Meng, Ning, Grimm, Dirk

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Every little bit helps: A single-residue switch in a vascular AAV enables blood-brain barrier penetration von Grimm, Dirk, Nonnenmacher, Mathieu

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Sodium taurocholate cotransporting polypeptide is the limiting host factor of hepatitis B virus infection in macaque and pig hepatocytes von Lempp, Florian A., Wiedtke, Ellen, Qu, Bingqian, Roques, Pierre, Chemin, Isabelle, Vondran, Florian W. R., Le Grand, Roger, Grimm, Dirk, Urban, Stephan

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Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models von Hakim, Chady H., Kumar, Sandeep R. P., Pérez-López, Dennis O., Wasala, Nalinda B., Zhang, Dong, Yue, Yongping, Teixeira, James, Pan, Xiufang, Zhang, Keqing, Million, Emily D., Nelson, Christopher E., Metzger, Samantha, Han, Jin, Louderman, Jacqueline A., Schmidt, Florian, Feng, Feng, Grimm, Dirk, Smith, Bruce F., Yao, Gang, Yang, N. Nora, Gersbach, Charles A., Chen, Shi-jie, Herzog, Roland W., Duan, Dongsheng

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CRISPR/Cas9-mediated genome engineering: An adeno-associated viral (AAV) vector toolbox von Senís, Elena, Fatouros, Chronis, Große, Stefanie, Wiedtke, Ellen, Niopek, Dominik, Mueller, Ann-Kristin, Börner, Kathleen, Grimm, Dirk

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