Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases von Geurts, Aron M, Cost, Gregory J, Freyvert, Yevgeniy, Zeitler, Bryan, Miller, Jeffrey C, Choi, Vivian M, Jenkins, Shirin S, Wood, Adam, Cui, Xiaoxia, Meng, Xiangdong, Vincent, Anna, Lam, Stephen, Michalkiewicz, Mieczyslaw, Schilling, Rebecca, Foeckler, Jamie, Kalloway, Shawn, Weiler, Hartmut, Ménoret, Séverine, Anegon, Ignacio, Davis, Gregory D, Zhang, Lei, Rebar, Edward J, Gregory, Philip D, Urnov, Fyodor D, Jacob, Howard J, Buelow, Roland

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Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells von Hoban, Megan D., Cost, Gregory J., Mendel, Matthew C., Romero, Zulema, Kaufman, Michael L., Joglekar, Alok V., Ho, Michelle, Lumaquin, Dianne, Gray, David, Lill, Georgia R., Cooper, Aaron R., Urbinati, Fabrizia, Senadheera, Shantha, Zhu, Allen, Liu, Pei-Qi, Paschon, David E., Zhang, Lei, Rebar, Edward J., Wilber, Andrew, Wang, Xiaoyan, Gregory, Philip D., Holmes, Michael C., Reik, Andreas, Hollis, Roger P., Kohn, Donald B.

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Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases von Hauschild, Janet, Petersen, Bjoern, Santiago, Yolanda, Queisser, Anna-Lisa, Carnwath, Joseph W, Lucas-Hahn, Andrea, Zhang, Lei, Meng, Xiangdong, Gregory, Philip D, Schwinzer, Reinhard, Cost, Gregory J, Niemann, Heiner

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In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration von Cristea, Sandra, Freyvert, Yevgeniy, Santiago, Yolanda, Holmes, Michael C., Urnov, Fyodor D., Gregory, Philip D., Cost, Gregory J.

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Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation von Sexton, Alec N, Regalado, Samuel G, Lai, Christine S, Cost, Gregory J, O'Neil, Colleen M, Urnov, Fyodor D, Gregory, Philip D, Jaenisch, Rudolf, Collins, Kathleen, Hockemeyer, Dirk

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Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells von Forster, Ryan, Chiba, Kunitoshi, Schaeffer, Lorian, Regalado, Samuel G., Lai, Christine S., Gao, Qing, Kiani, Samira, Farin, Henner F., Clevers, Hans, Cost, Gregory J., Chan, Andy, Rebar, Edward J., Urnov, Fyodor D., Gregory, Philip D., Pachter, Lior, Jaenisch, Rudolf, Hockemeyer, Dirk

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Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes von Aliaga Goltsman, Daniela S., Alexander, Lisa M., Lin, Jyun-Liang, Fregoso Ocampo, Rodrigo, Freeman, Benjamin, Lamothe, Rebecca C., Perez Rivas, Andres, Temoche-Diaz, Morayma M., Chadha, Shailaja, Nordenfelt, Natalie, Janson, Owen P., Barr, Ian, Devoto, Audra E., Cost, Gregory J., Butterfield, Cristina N., Thomas, Brian C., Brown, Christopher T.

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Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases von Liu, Pei-Qi, Chan, Edmond M, Cost, Gregory J, Zhang, Lin, Wang, Jianbin, Miller, Jeffrey C, Guschin, Dmitry Y, Reik, Andreas, Holmes, Michael C, Mott, John E, Collingwood, Trevor N, Gregory, Philip D

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Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases von Remy, Séverine, Tesson, Laurent, Menoret, Séverine, Usal, Claire, De Cian, Anne, Thepenier, Virginie, Thinard, Reynald, Baron, Daniel, Charpentier, Marine, Renaud, Jean-Baptiste, Buelow, Roland, Cost, Gregory J, Giovannangeli, Carine, Fraichard, Alexandre, Concordet, Jean-Paul, Anegon, Ignacio

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Generation of Gene-Specific Mutated Rats Using Zinc-Finger Nucleases von Geurts, Aron M., Cost, Gregory J., Rémy, Séverine, Cui, Xiaoxia, Tesson, Laurent, Usal, Claire, Ménoret, Séverine, Jacob, Howard J., Anegon, Ignacio, Buelow, Roland

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Genetic engineering of human pluripotent cells using TALE nucleases von Jaenisch, Rudolf, Hockemeyer, Dirk, Wang, Haoyi, Kiani, Samira, Lai, Christine S, Gao, Qing, Cassady, John P, Cost, Gregory J, Zhang, Lei, Santiago, Yolanda, Miller, Jeffrey C, Zeitler, Bryan, Cherone, Jennifer M, Meng, Xiangdong, Hinkley, Sarah J, Rebar, Edward J, Gregory, Philip D, Urnov, Fyodor D

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Sequence-Directed DNA Translocation by Purified FtsK von Pease, Paul J, Levy, Oren, Cost, Gregory J, Gore, Jeff, Ptacin, Jerod L, Sherratt, David, Bustamante, Carlos, Cozzarelli, Nicholas R

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Knockout rats generated by embryo microinjection of TALENs von Tesson, Laurent, Usal, Claire, Ménoret, Séverine, Leung, Elo, Niles, Brett J, Remy, Séverine, Santiago, Yolanda, Vincent, Anna I, Meng, Xiangdong, Zhang, Lei, Gregory, Philip D, Anegon, Ignacio, Cost, Gregory J

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A TALE nuclease architecture for efficient genome editing von Rebar, Edward J, Miller, Jeffrey C, Tan, Siyuan, Qiao, Guijuan, Barlow, Kyle A, Wang, Jianbin, Xia, Danny F, Meng, Xiangdong, Paschon, David E, Leung, Elo, Hinkley, Sarah J, Dulay, Gladys P, Hua, Kevin L, Ankoudinova, Irina, Cost, Gregory J, Urnov, Fyodor D, Zhang, H Steve, Holmes, Michael C, Zhang, Lei, Gregory, Philip D

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Characterization of immunoglobulin heavy chain knockout rats von Ménoret, Séverine, Iscache, Anne-L, Tesson, Laurent, Rémy, Séverine, Usal, Claire, Osborn, Michel J, Cost, Gregory J, Brüggemann, Marianne, Buelow, Roland, Anegon, Ignacio

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Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency von Li, Yanfeng, Guha, Chandan, Asp, Patrik, Wang, Xia, Tchaikovskya, Tatyana L, Kim, Kenneth, Mendel, Matthew, Cost, Gregory J, Perlmutter, David H, Roy-Chowdhury, Namita, Fox, Ira J, Conway, Anthony, Roy-Chowdhury, Jayanta

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Translating dosage compensation to trisomy 21 von Jiang, Jun, Jing, Yuanchun, Cost, Gregory J., Chiang, Jen-Chieh, Kolpa, Heather J., Cotton, Allison M., Carone, Dawn M., Carone, Benjamin R., Shivak, David A., Guschin, Dmitry Y., Pearl, Jocelynn R., Rebar, Edward J., Byron, Meg, Gregory, Philip D., Brown, Carolyn J., Urnov, Fyodor D., Hall, Lisa L., Lawrence, Jeanne B.

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Dissection of splicing regulation at an endogenous locus by zinc-finger nuclease-mediated gene editing von Cristea, Sandra, Gregory, Philip D, Urnov, Fyodor D, Cost, Gregory J

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Targeting of Human Retrotransposon Integration Is Directed by the Specificity of the L1 Endonuclease for Regions of Unusual DNA Structure von Cost, Gregory J, Boeke, Jef D

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Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology von Orlando, Salvatore J, Santiago, Yolanda, DeKelver, Russell C, Freyvert, Yevgeniy, Boydston, Elizabeth A, Moehle, Erica A, Choi, Vivian M, Gopalan, Sunita M, Lou, Jacqueline F, Li, James, Miller, Jeffrey C, Holmes, Michael C, Gregory, Philip D, Urnov, Fyodor D, Cost, Gregory J

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