Triple-negative breast cancer cells rely on kinase-independent functions of CDK8 to evade NK-cell-mediated tumor surveillance von Knab, Vanessa Maria, Gotthardt, Dagmar, Klein, Klara, Grausenburger, Reinhard, Heller, Gerwin, Menzl, Ingeborg, Prinz, Daniela, Trifinopoulos, Jana, List, Julia, Fux, Daniela, Witalisz-Siepracka, Agnieszka, Sexl, Veronika

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Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia von Kollmann, Sebastian, Grundschober, Eva, Maurer, Barbara, Warsch, Wolfgang, Grausenburger, Reinhard, Edlinger, Leo, Huuhtanen, Jani, Lagger, Sabine, Hennighausen, Lothar, Valent, Peter, Decker, Thomas, Strobl, Birgit, Mueller, Mathias, Mustjoki, Satu, Hoelbl-Kovacic, Andrea, Sexl, Veronika

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Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis von Jurkin, Jennifer, Zupkovitz, Gordin, Lagger, Sabine, Grausenburger, Reinhard, Hagelkruys, Astrid, Kenner, Lukas, Seiser, Christian

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A kinase-independent role for CDK8 in BCR-ABL1+ leukemia von Menzl, Ingeborg, Zhang, Tinghu, Berger-Becvar, Angelika, Grausenburger, Reinhard, Heller, Gerwin, Prchal-Murphy, Michaela, Edlinger, Leo, Knab, Vanessa M., Uras, Iris Z., Grundschober, Eva, Bauer, Karin, Roth, Mareike, Skucha, Anna, Liu, Yao, Hatcher, John M., Liang, Yanke, Kwiatkowski, Nicholas P., Fux, Daniela, Hoelbl-Kovacic, Andrea, Kubicek, Stefan, Melo, Junia V., Valent, Peter, Weichhart, Thomas, Grebien, Florian, Zuber, Johannes, Gray, Nathanael S., Sexl, Veronika

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T Cell-Intrinsic CDK6 Is Dispensable for Anti-Viral and Anti-Tumor Responses In Vivo von Klein, Klara, Witalisz-Siepracka, Agnieszka, Gotthardt, Dagmar, Agerer, Benedikt, Locker, Felix, Grausenburger, Reinhard, Knab, Vanessa Maria, Bergthaler, Andreas, Sexl, Veronika

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High activation of STAT5A drives peripheral T-cell lymphoma and leukemia von Maurer, Barbara, Nivarthi, Harini, Wingelhofer, Bettina, Pham, Ha Thi Thanh, Schlederer, Michaela, Suske, Tobias, Grausenburger, Reinhard, Schiefer, Ana-Iris, Prchal-Murphy, Michaela, Chen, Doris, Winkler, Susanne, Merkel, Olaf, Kornauth, Christoph, Hofbauer, Maximilian, Hochgatterer, Birgit, Hoermann, Gregor, Hoelbl-Kovacic, Andrea, Prochazkova, Jana, Lobello, Cosimo, Cumaraswamy, Abbarna A, Latzka, Johanna, Kitzwögerer, Melitta, Chott, Andreas, Janikova, Andrea, Pospíšilova, Šárka, Loizou, Joanna I, Kubicek, Stefan, Valent, Peter, Kolbe, Thomas, Grebien, Florian, Kenner, Lukas, Gunning, Patrick T, Kralovics, Robert, Herling, Marco, Müller, Mathias, Rülicke, Thomas, Sexl, Veronika, Moriggl, Richard

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The Cyclin-Dependent Kinase Inhibitor p21 Is a Crucial Target for Histone Deacetylase 1 as a Regulator of Cellular Proliferation von Zupkovitz, Gordin, Grausenburger, Reinhard, Brunmeir, Reinhard, Senese, Silvia, Tischler, Julia, Jurkin, Jennifer, Rembold, Martina, Meunier, Dominique, Egger, Gerda, Lagger, Sabine, Chiocca, Susanna, Propst, Fritz, Weitzer, Georg, Seiser, Christian

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Negative and Positive Regulation of Gene Expression by Mouse Histone Deacetylase 1 von Zupkovitz, Gordin, Tischler, Julia, Posch, Markus, Sadzak, Iwona, Ramsauer, Katrin, Egger, Gerda, Grausenburger, Reinhard, Schweifer, Norbert, Chiocca, Susanna, Decker, Thomas, Seiser, Christian

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ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling von Kuster, Lilian, Grausenburger, Reinhard, Fuka, Gerhard, Kaindl, Ulrike, Krapf, Gerd, Inthal, Andrea, Mann, Georg, Kauer, Maximilian, Rainer, Johannes, Kofler, Reinhard, Hall, Andrew, Metzler, Markus, Meyer, Lüder Hinrich, Meyer, Claus, Harbott, Jochen, Marschalek, Rolf, Strehl, Sabine, Haas, Oskar A., Panzer-Grümayer, Renate

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Small sizes and indolent evolutionary dynamics challenge the potential role of P2RY8-CRLF2–harboring clones as main relapse-driving force in childhood ALL von Morak, Maria, Attarbaschi, Andishe, Fischer, Susanna, Nassimbeni, Christine, Grausenburger, Reinhard, Bastelberger, Stephan, Krentz, Stefanie, Cario, Gunnar, Kasper, David, Schmitt, Klaus, Russell, Lisa J., Pötschger, Ulrike, Stanulla, Martin, Eckert, Conny, Mann, Georg, Haas, Oskar A., Panzer-Grümayer, Renate

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Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells von Leone, Dino P, Genoud, S.téphane, Atanasoski, Suzana, Grausenburger, Reinhard, Berger, Philipp, Metzger, Daniel, Macklin, Wendy B, Chambon, Pierre, Suter, Ueli

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SBNO2 is a critical mediator of STAT3-driven hematological malignancies von Brandstoetter, Tania, Schmoellerl, Johannes, Grausenburger, Reinhard, Kollmann, Sebastian, Doma, Eszter, Huuhtanen, Jani, Klampfl, Thorsten, Eder, Thomas, Grebien, Florian, Hoermann, Gregor, Zuber, Johannes, Mustjoki, Satu, Maurer, Barbara, Sexl, Veronika

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A STAT5B–CD9 axis determines self-renewal in hematopoietic and leukemic stem cells von Kollmann, Sebastian, Grausenburger, Reinhard, Klampfl, Thorsten, Prchal-Murphy, Michaela, Bastl, Klavdija, Pisa, Hanja, Knab, Vanessa M., Brandstoetter, Tania, Doma, Eszter, Sperr, Wolfgang R., Lagger, Sabine, Farlik, Matthias, Moriggl, Richard, Valent, Peter, Halbritter, Florian, Kollmann, Karoline, Heller, Gerwin, Maurer, Barbara, Sexl, Veronika

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STAT5BN642H is a driver mutation for T cell neoplasia von Pham, Ha Thi Thanh, Maurer, Barbara, Prchal-Murphy, Michaela, Grausenburger, Reinhard, Grundschober, Eva, Javaheri, Tahereh, Nivarthi, Harini, Boersma, Auke, Kolbe, Thomas, Elabd, Mohamed, Halbritter, Florian, Pencik, Jan, Kazemi, Zahra, Grebien, Florian, Hengstschläger, Markus, Kenner, Lukas, Kubicek, Stefan, Farlik, Matthias, Bock, Christoph, Valent, Peter, Müller, Mathias, Rülicke, Thomas, Sexl, Veronika, Moriggl, Richard

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CDK6 Antagonizes p53-Induced Responses during Tumorigenesis von Bellutti, Florian, Tigan, Anca-Sarmiza, Nebenfuehr, Sofie, Dolezal, Marlies, Zojer, Markus, Grausenburger, Reinhard, Hartenberger, Svenja, Kollmann, Sebastian, Doma, Eszter, Prchal-Murphy, Michaela, Uras, Iris Z, Höllein, Alexander, Neuberg, Donna S, Ebert, Benjamin L, Ringler, Anna, Mueller, Andre C, Loizou, Joanna I, Hinds, Philip W, Vogl, Claus, Heller, Gerwin, Kubicek, Stefan, Zuber, Johannes, Malumbres, Marcos, Farlik, Matthias, Villunger, Andreas, Kollmann, Karoline, Sexl, Veronika

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Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production von Grausenburger, Reinhard, Bilic, Ivan, Boucheron, Nicole, Zupkovitz, Gordin, El-Housseiny, Lamia, Tschismarov, Roland, Zhang, Yu, Rembold, Martina, Gaisberger, Martin, Hartl, Arnulf, Epstein, Michelle M, Matthias, Patrick, Seiser, Christian, Ellmeier, Wilfried

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CDK6 coordinates JAK2V617F mutant MPN via NF-κB and apoptotic networks von Uras, Iris Z., Maurer, Barbara, Nivarthi, Harini, Jodl, Philipp, Kollmann, Karoline, Prchal-Murphy, Michaela, Milosevic Feenstra, Jelena D., Zojer, Markus, Lagger, Sabine, Grausenburger, Reinhard, Grabner, Beatrice, Holly, Raimund, Kavirayani, Anoop, Bock, Christoph, Gisslinger, Heinz, Valent, Peter, Kralovics, Robert, Sexl, Veronika

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Predicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemia von Hajingabo, Leon Juvenal, Daakour, Sarah, Martin, Maud, Grausenburger, Reinhard, Panzer-Grümayer, Renate, Dequiedt, Franck, Simonis, Nicolas, Twizere, Jean-Claude

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Clofarabine Has a Superior Therapeutic Window as compared to Gemcitabine in Preclinical Bladder Cancer Models von Gutmann, Michael, Ertl, Iris E., Herek, Paula, Vician, Petra, Pirker, Christine, Nössing, Christoph, Brettner, Robert, Lemberger, Ursula, Grausenburger, Reinhard, Batlogg, Kai, Baumfried, Oliver, Prantl, Isabella, Singh, Neha, Laukhtina, Ekaterina, Oszwald, André, Wasinger, Gabriel, Compérat, Eva, Berger, Walter, Shariat, Shahrokh F., Englinger, Bernhard

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A robust approach for the generation of functional hematopoietic progenitor cell lines to model leukemic transformation von Doma, Eszter, Mayer, Isabella Maria, Brandstoetter, Tania, Maurer, Barbara, Grausenburger, Reinhard, Menzl, Ingeborg, Zojer, Markus, Hoelbl-Kovacic, Andrea, Carlsson, Leif, Heller, Gerwin, Kollmann, Karoline, Sexl, Veronika

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