Chemical Upcycling of Expired Pharmaceuticals as a Source of Value-Added Chemicals for Organic Synthesis and Medicinal Chemistry von Abad-Grillo, Teresa, McNaughton-Smith, Grant

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ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice von Stocker, Jonathan W., De Franceschi, Lucia, McNaughton-Smith, Grant A., Corrocher, Roberto, Beuzard, Yves, Brugnara, Carlo

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Fused oxazepine-naphthoquinones as novel cytotoxic agents with diverse modes of action in yeast von Anaissi-Afonso, Laura, Santana-Sosa, Silvia, Lorenzo-Castrillejo, Isabel, McNaughton-Smith, Grant, Machín, Félix

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In vitro activity of 1H-phenalen-1-one derivatives against Leishmania spp. and evidence of programmed cell death von López-Arencibia, Atteneri, Reyes-Batlle, María, Freijo, Mónica B, Sifaoui, Ines, Bethencourt-Estrella, Carlos J, Rizo-Liendo, Aitor, Chiboub, Olfa, McNaughton-Smith, Grant, Lorenzo-Morales, Jacob, Abad-Grillo, Teresa, Piñero, José E

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Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics von Hanessian, Stephen, McNaughton-Smith, Grant, Lombart, Henry-Georges, Lubell, William D.

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Novel Inhibitors of the Gardos Channel for the Treatment of Sickle Cell Disease von McNaughton-Smith, Grant A, Burns, J. Ford, Stocker, Jonathan W, Rigdon, Gregory C, Creech, Christopher, Arrington, Susan, Shelton, Tara, de Franceschi, Lucia

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Process Development and Optimization for Production of a Potassium Ion Channel Blocker, ICA-17043 von Mobele, Bingidimi I, Venkatraman, Sripathy, McNaughton-Smith, Grant, Gibb, Cameron, Ulysse, Luckner G, Lindmark, Carl A, Shaw, Stephen, Marron, Brian, Spear, Kerry, Suto, Mark J

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Design, synthesis and evaluation of amino-substituted 1H-phenalen-1-ones as anti-leishmanial agents von Freijo, Mónica Blanco, López-Arencibia, Atteneri, Piñero, José E., McNaughton-Smith, Grant, Abad-Grillo, Teresa

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Plant defensin Pv D 1 modulates the membrane composition of breast tumour-derived exosomes von Skalska, Julia, Oliveira, Filipa D., Figueira, Tiago N., Mello, Érica O., Gomes, Valdirene M., McNaughton-Smith, Grant, Castanho, Miguel A. R. B., Gaspar, Diana

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Plant defensin D modulates the membrane composition of breast tumour-derived exosomes von Skalska, Julia, Oliveira, Filipa D, Figueira, Tiago N, Mello, Érica O, Gomes, Valdirene M, McNaughton-Smith, Grant, Castanho, Miguel A. R. B, Gaspar, Diana

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Plant defensin PvD1 modulates the membrane composition of breast tumour-derived exosomes von Skalska, Julia, Oliveira, Filipa, Figueira, Tiago, Mello, Érica O., Gomes, Valdirene M., McNaughton-Smith, Grant, Castanho, Miguel, Gaspar, Diana

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Anticoccidial efficacy of Canary rue (Ruta pinnata) extracts against the caprine apicomplexan Eimeria ninakohlyakimovae1 von López, Adassa M, Muñoz, María C, Molina, José M, Hermosilla, Carlos, Taubert, Anja, Zárate, Rafael, Hildebrandt, Inna, McNaughton-Smith, Grant, Eiroa, José L, Ruiz, Antonio

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Anticoccidial efficacy of Canary rue ( Ruta pinnata ) extracts against the caprine apicomplexan Eimeria ninakohlyakimovae 1 von López, Adassa M, Muñoz, María C, Molina, José M, Hermosilla, Carlos, Taubert, Anja, Zárate, Rafael, Hildebrandt, Inna, McNaughton-Smith, Grant, Eiroa, José L, Ruiz, Antonio

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Identification of N-acyl quinolin-2(1H)-ones as new selective agents against clinical isolates of Acanthamoeba keratitis von Reyes-Batlle, María, Freijo, Mónica Blanco, López-Arencibia, Atteneri, Lorenzo-Morales, Jacob, McNaughton-Smith, Grant, Piñero, José E., Abad-Grillo, Teresa

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Chemical-proteomics Identify Peroxiredoxin-1 as an Actionable Target in Triple-negative Breast Cancer von Spínola-Lasso, Elena, Montero, Juan Carlos, Jiménez-Monzón, Roberto, Estévez, Francisco, Quintana, José, Guerra, Borja, Elokely, Khaled M, León, Francisco, Del Rosario, Henoc, Fernández-Pérez, Leandro, López, Manuel Rodríguez, Díaz-Chico, Bonifacio Nicolás, McNaughton-Smith, Grant, Pandiella, Atanasio, Díaz-Chico, Juan Carlos

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Synthesis of (4 S)-hydroxymethyl-(2 R)-(2-propyl)-butyrolactone: A quest for a practical route to an important hydroxyethylene isostere chiron von Hanessian, Stephen, Abad-Grillo, Teresa, McNaughton-Smith, Grant

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JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous le... von Aranda-Tavío, Haidée, Recio, Carlota, Martín-Acosta, Pedro, Guerra-Rodríguez, Miguel, Brito-Casillas, Yeray, Blanco, Rosa, Junco, Vanessa, León, Javier, Montero, Juan Carlos, Gandullo-Sánchez, Lucía, McNaughton-Smith, Grant, Zapata, Juan Manuel, Pandiella, Atanasio, Amesty, Angel, Estévez-Braun, Ana, Fernández-Pérez, Leandro, Guerra, Borja

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New phenalenone analogues with improved activity against Leishmania species von López-Arencibia, Atteneri, Bethencourt-Estrella, Carlos J., Freijo, Mónica B., Reyes-Batlle, María, Sifaoui, Ines, Nicolás-Hernández, Desirée San, McNaughton-Smith, Grant, Lorenzo-Morales, Jacob, Abad-Grillo, Teresa, Piñero, José E.

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Evaluation of substituted phenalenone analogues as antiplasmodial agents von Gutiérrez, David, Flores, Ninoska, Abad-Grillo, Teresa, McNaughton-Smith, Grant

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Anticoccidial efficacy of Canary rue (Ruta pinnata) extracts against the caprine apicomplexan Eimeria ninakohlyakimovae von López, Adassa M, Muñoz, María C, Molina, José M, Hermosilla, Carlos, Taubert, Anja, Zárate, Rafael, Hildebrandt, Inna, McNaughton-Smith, Grant, Eiroa, José L, Ruiz, Antonio

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