An improved process for the release of synthetic DNA sequences from a solid-phase capture support von Grajkowski, Andrzej, Cawrse, Brian M., Takahashi, Mayumi, Beaucage, Serge L.

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Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome von Abdul-Sater, Ali A, Tattoli, Ivan, Jin, Lei, Grajkowski, Andrzej, Levi, Assaf, Koller, Beverly H, Allen, Irving C, Beaucage, Serge L, Fitzgerald, Katherine A, Ting, Jenny P -Y, Cambier, John C, Girardin, Stephen E, Schindler, Christian

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A Novel Function of RNAs Arising From the Long Terminal Repeat of Human Endogenous Retrovirus 9 in Cell Cycle Arrest von Xu, Lai, Elkahloun, Abdel G, Candotti, Fabio, Grajkowski, Andrzej, Beaucage, Serge L, Petricoin, Emanuel F, Calvert, Valerie, Juhl, Hartmut, Mills, Frederick, Mason, Karen, Shastri, Neal, Chik, Josh, Xu, Cynthia, Rosenberg, Amy S

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An improved process for the release of synthetic DNA sequences from a solid-phase capture support von Grajkowski, Andrzej, Cawrse, Brian M., Takahashi, Mayumi, Beaucage, Serge L.

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Hydroxyalkylated phosphoramidate, phosphoramidothioate and phosphorodiamidothioate derivatives as thiophosphate protecting groups in the development of thermolytic DNA prodrugs von Grajkowski, Andrzej, Cieślak, Jacek, Gapeev, Alexei, Beaucage, Serge L.

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Innovative 2′- O -Imino-2-propanoate-Protecting Group for Effective Solid-Phase Synthesis and 2′- O -Deprotection of RNA Sequences von Takahashi, Mayumi, Grajkowski, Andrzej, Cawrse, Brian M., Beaucage, Serge L.

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The 4-(N-Dichloroacetyl-N-methylamino)benzyloxymethyl Group for 2‘-Hydroxyl Protection of Ribonucleosides in the Solid-Phase Synthesis of Oligoribonucleotides von Cieślak, Jacek, Grajkowski, Andrzej, Kauffman, Jon S, Duff, Robert J, Beaucage, Serge L

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Use of thermolytic protective groups to prevent G-tetrad formation in CpG ODN type D: structural studies and immunomodulatory activity in primates von Puig, Montserrat, Grajkowski, Andrzej, Boczkowska, Malgorzata, Ausín, Cristina, Beaucage, Serge L, Verthelyi, Daniela

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Innovative 2′‑O‑Imino-2-propanoate-Protecting Group for Effective Solid-Phase Synthesis and 2′‑O‑Deprotection of RNA Sequences von Takahashi, Mayumi, Grajkowski, Andrzej, Cawrse, Brian M, Beaucage, Serge L

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Deoxyribonucleoside Cyclic N-Acylphosphoramidites as a New Class of Monomers for the Stereocontrolled Synthesis of Oligothymidylyl- and Oligodeoxycytidylyl- Phosphorothioates von Wilk, Andrzej, Grajkowski, Andrzej, Phillips, Lawrence R, Beaucage, Serge L

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An expedient process for reducing the formation of process-related impurities during solid-phase synthesis of potential nucleic acid-based drugs von Grajkowski, Andrzej, Takahashi, Mayumi, Cawrse, Brian M., Beaucage, Serge L.

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Solid-Phase Purification of Synthetic DNA Sequences von Grajkowski, Andrzej, Cieslak, Jacek, Beaucage, Serge L.

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A Cyclopentane Conformational Restraint for a Peptide Nucleic Acid:  Design, Asymmetric Synthesis, and Improved Binding Affinity to DNA and RNA von Myers, Michael C, Witschi, Mark A, Larionova, Nataliya V, Franck, John M, Haynes, Russell D, Hara, Toshiaki, Grajkowski, Andrzej, Appella, Daniel H

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Thermolytic 4-Methylthio-1-butyl Group for Phosphate/Thiophosphate Protection in Solid-Phase Synthesis of DNA Oligonucleotides von Cieślak, Jacek, Grajkowski, Andrzej, Livengood, Victor, Beaucage, Serge L

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An improved phosphoramidite approach for the chemical synthesis of 3′,5′-cyclic diguanylic acid von Grajkowski, Andrzej, Takahashi, Mayumi, Kaczyński, Tomasz, Srivastava, Suresh C., Beaucage, Serge L.

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The 3-(N-tert-Butylcarboxamido)-1-propyl Group as an Attractive Phosphate/Thiophosphate Protecting Group for Solid-Phase Oligodeoxyribonucleotide Synthesis von Wilk, Andrzej, Chmielewski, Marcin K, Grajkowski, Andrzej, Phillips, Lawrence R, Beaucage, Serge L

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The 4-[N-Methyl-N-(2,2,2-trifluoroacetyl)amino]butyl Group as an Alternative to the 2-Cyanoethyl Group for Phosphate Protection in the Synthesis of Oligodeoxyribonucleotides von Wilk, Andrzej, Grajkowski, Andrzej, Phillips, Lawrence R, Beaucage, Serge L

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An Alternate Process for the Solid‐Phase Synthesis and Solid‐Phase Purification of Synthetic Nucleic Acid Sequences von Cawrse, Brian M., Takahashi, Mayumi, Grajkowski, Andrzej, Beaucage, Serge L.

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Use of Arabinonucleosides for Development and Implementation of a Novel 2′‐O‐Protecting Group for Efficient Solid‐Phase Synthesis and 2′‐O‐Deprotection of RNA Sequences... von Takahashi, Mayumi, Cawrse, Brian M., Grajkowski, Andrzej, Beaucage, Serge L.

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Protection of the 2′-Hydroxy Function of Ribonucleosides as an Iminooxymethyl Propanoate and Its 2′-O-Deprotection through an Intramolecular Decarboxylative Elimination Process von Cieślak, Jacek, Grajkowski, Andrzej, Ausín, Cristina, Beaucage, Serge L.

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