North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies von Shah, Urvi A., Chung, Elaine Y., Giricz, Orsi, Pradhan, Kith, Kataoka, Keisuke, Gordon-Mitchell, Shanisha, Bhagat, Tushar D., Mai, Yun, Wei, Yongqiang, Ishida, Elise, Choudhary, Gaurav S., Joseph, Ancy, Rice, Ronald, Gitego, Nadege, Parrish, Crystall, Bartenstein, Matthias, Goel, Swati, Mantzaris, Ioannis, Shastri, Aditi, Derman, Olga, Binder, Adam, Gritsman, Kira, Kornblum, Noah, Braunschweig, Ira, Bhagat, Chirag, Hall, Jeff, Graber, Armin, Ratner, Lee, Wang, Yanhua, Ogawa, Seishi, Verma, Amit, Ye, B. Hilda, Janakiram, Murali

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A large scale analysis of information-theoretic network complexity measures using chemical structures von Dehmer, Matthias, Barbarini, Nicola, Varmuza, Kurt, Graber, Armin

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Sample size and statistical power considerations in high-dimensionality data settings: a comparative study of classification algorithms von Guo, Yu, Graber, Armin, McBurney, Robert N, Balasubramanian, Raji

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Bioinformatics Analysis of Targeted Metabolomics—Uncovering Old and New Tales of Diabetic Mice under Medication von Altmaier, Elisabeth, Ramsay, Steven L, Graber, Armin, Mewes, Hans-Werner, Weinberger, Klaus M, Suhre, Karsten

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Integrative network biology: graph prototyping for co-expression cancer networks von Kugler, Karl G, Mueller, Laurin A J, Graber, Armin, Dehmer, Matthias

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Stem cell mutations can be detected in myeloma patients years before onset of secondary leukemias von Sridharan, Ashwin, Schinke, Carolina D., Georgiev, George, Da Silva Ferreira, Mariana, Thiruthuvanathan, Victor, MacArthur, Ian, Bhagat, Tushar D., Choudhary, Gaurav S., Aluri, Srinivas, Chen, Jiahao, Pradhan, Kith, Xia, Yu, Panjikaran, Maya, Sims, Gregory, Bhagat, Chirag K., Bender, Ryan, Keeler, Lauryn, Graber, Armin, Heuck, Christoph, Fletcher, Frederick A., Alapat, Daisy, Weinhold, Niels, Johnson, Sarah K., Wickrema, Amittha, Barlogie, Bart, Morgan, Gareth J., Shastri, Aditi, Steidl, Ulrich, Will, Britta, Verma, Amit

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New polynomial-based molecular descriptors with low degeneracy von Dehmer, Matthias, Mueller, Laurin A J, Graber, Armin

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Effects of Pooling Samples on the Performance of Classification Algorithms : A Comparative Study von Baumgartner, Christian, Kusonmano, Kanthida, Graber, Armin, Liedl, Klaus R., Dehmer, Matthias, Netzer, Michael

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MUMAL: multivariate analysis in shotgun proteomics using machine learning techniques von Cerqueira, Fabio R, Ferreira, Ricardo S, Oliveira, Alcione P, Gomes, Andreia P, Ramos, Humberto J O, Graber, Armin, Baumgartner, Christian

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The Impact of Sample Storage Time on Estimates of Association in Biomarker Discovery Studies von Kugler, Karl G, Hackl, Werner O, Mueller, Laurin Aj, Fiegl, Heidi, Graber, Armin, Pfeiffer, Ruth M

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Repotrectinib in ROS1 Fusion–Positive Non–Small-Cell Lung Cancer von Drilon, Alexander, Camidge, D. Ross, Lin, Jessica J., Kim, Sang-We, Solomon, Benjamin J., Dziadziuszko, Rafal, Besse, Benjamin, Goto, Koichi, de Langen, Adrianus Johannes, Wolf, Jürgen, Lee, Ki Hyeong, Popat, Sanjay, Springfeld, Christoph, Nagasaka, Misako, Felip, Enriqueta, Yang, Nong, Velcheti, Vamsidhar, Lu, Shun, Kao, Steven, Dooms, Christophe, Krebs, Matthew G., Yao, Wenxiu, Beg, Muhammad Shaalan, Hu, Xiufeng, Moro-Sibilot, Denis, Cheema, Parneet, Stopatschinskaja, Shanna, Mehta, Minal, Trone, Denise, Graber, Armin, Sims, Gregory, Yuan, Yong, Cho, Byoung Chul

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Development of an NGS assay to detect MRD in hematologic malignancies von Yu, James, Sitlani, Parth, Nakashe, Prachi, Sims, Gregory, Scott, Christopher, Graber, Armin, Falk, Jeffrey

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Repotrectinib in ROS1 Fusion–Positive Non–Small-Cell Lung Cancer von Drilon, Alexander, Camidge, D. Ross, Lin, Jessica J, Kim, Sang-We, Solomon, Benjamin J, Dziadziuszko, Rafal, Besse, Benjamin, Goto, Koichi, de Langen, Adrianus Johannes, Wolf, Jürgen, Lee, Ki Hyeong, Popat, Sanjay, Springfeld, Christoph, Nagasaka, Misako, Felip, Enriqueta, Yang, Nong, Velcheti, Vamsidhar, Lu, Shun, Kao, Steven, Dooms, Christophe, Krebs, Matthew G, Yao, Wenxiu, Beg, Muhammad Shaalan, Hu, Xiufeng, Moro-Sibilot, Denis, Cheema, Parneet, Stopatschinskaja, Shanna, Mehta, Minal, Trone, Denise, Graber, Armin, Sims, Gregory, Yuan, Yong, Cho, Byoung Chul

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MUMAL2: Improving sensitivity in shotgun proteomics using cost sensitive artificial neural networks and a threshold selector algorithm von Cerqueira, Fabio Ribeiro, Ricardo, Adilson Mendes, de Paiva Oliveira, Alcione, Graber, Armin, Baumgartner, Christian

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B-cell enrichment for next generation sequencing (NGS): An approach to detect actionable low frequency variants in B-cell lymphomas von Panjikaran, Maya P, Orosco, Claire, Kwok, Brian, Xia, Yu, Keeler, Lauryn, Petersen, Paris, Sims, Gregory, Falk, Jeffrey, Scott, Christopher, Graber, Armin

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Abstract 1321: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC for treatment of cancers with abnormal HGF/MET signaling von Zhai, Dayong, Rogers, Evan, Deng, Wei, Zhang, Xin, Lee, Dong, Ung, Jane, Zhang, Han, Liu, Jing, Lu, Yuelie, Huang, John, Graber, Armin, Zimmerman, Zach, Lim, John, Whitten, Jeffrey, Cui, J. Jean

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Development and Validation of an Rnaseq NGS Assay to Comprehensively Detect Clinically Relevant ALL Gene Fusions von Sitlani, Parth, Panjikaran, Maya, Weiner, Dana, Orosco, Claire Orosco, Cherukuri, Durga, Keeler, Lauryn, Dedek, Matthew, Xia, Yu, Graber, Armin, Scott, Christopher, Falk, Jeffrey

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Abstract 3388: Analytical validation and clinical verification of phosphoprotein biomarker modulation using a novel preservation system-based flow cytometry assay in multiple myelo... von Pahuja, Anil, Sarikonda, Shyam, Lee, Benjamin, Graber, Armin, Tangri, Shabnam, Dakappagari, Naveen

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A new rule-based algorithm for identifying metabolic markers in prostate cancer using tandem mass spectrometry von Osl, Melanie, Dreiseitl, Stephan, Pfeifer, Bernhard, Weinberger, Klaus, Klocker, Helmut, Bartsch, Georg, Schäfer, Georg, Tilg, Bernhard, Graber, Armin, Baumgartner, Christian

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Abstract CT068: Phase Ib/II combination study of APR-246 and azacitidine (AZA) in patients with TP53 mutant myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) von Sallman, David A., DeZern, Amy, Sweet, Kendra, Steensma, David P., Cluzeau, Thomas, Sekeres, Mikkael, Garcia-Manero, Guillermo, Roboz, Gail, McLemore, Amy, McGraw, Kathy, Puskas, John, Zhang, Ling, Bhagat, Chirag, Graber, Armin, Ali, Najla H. Al, Padron, Eric, Tell, Roger, Lancet, Jeffrey E., Fenaux, Pierre, List, Alan F., Komrokji, Rami S.

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