Regulation of SIRT6 protein levels by nutrient availability von Kanfi, Yariv, Shalman, Ronnie, Peshti, Victoria, Pilosof, Shmuel N., Gozlan, Yosi M., Pearson, Kevin J., Lerrer, Batya, Moazed, Danesh, Marine, Jean-Christophe, de Cabo, Rafael, Cohen, Haim Y.

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Regulation of SIRT1 protein levels by nutrient availability von Kanfi, Yariv, Peshti, Victoria, Gozlan, Yosi M., Rathaus, Moran, Gil, Reuven, Cohen, Haim Y.

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Avidity optimization of a MAGE‐A1‐specific TCR with somatic hypermutation von Bassan, David, Gozlan, Yosi Meir, Sharbi‐Yunger, Adi, Tzehoval, Esther, Greenstein, Erez, Bitan, Lidor, Friedman, Nir, Eisenbach, Lea

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DSP107 combines inhibition of CD47/SIRPα axis with activation of 4-1BB to trigger anticancer immunity von Cendrowicz, Ewa, Jacob, Lisa, Greenwald, Shirley, Tamir, Ami, Pecker, Iris, Tabakman, Rinat, Ghantous, Lucy, Tamir, Liat, Kahn, Roy, Avichzer, Jasmine, Aronin, Alexandra, Amsili, Shira, Zorde-Khvalevsky, Elina, Gozlan, Yosi, Vlaming, Martijn, Huls, Gerwin, van Meerten, Tom, Dranitzki, Michal Elhalel, Foley-Comer, Adam, Pereg, Yaron, Peled, Amnon, Chajut, Ayelet, Bremer, Edwin

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Optimizing T‐cell receptor avidity with somatic hypermutation von Bassan, David, Gozlan, Yosi Meir, Sharbi‐Yunger, Adi, Tzehoval, Esther, Eisenbach, Lea

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SUV39H1 disruption imparts functional persistence to CD28-costimulated human CAR T cells von Jain, Nayan, Zhao, Zeguo, Koche, Richard, Gozlan, Yosi, Brocks, David, Raveh-Sadka, Tali, Wells, Danny, Dobrin, Anton, Shi, Yuzhe, Lopez, Michael, Gunset, Gertrude, Sadelain, Michel

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Impact of steroid premedication on atezolizumab (atezo)-induced immune cell activation: A comparative analysis of IMpassion130 and IMpassion131 peripheral blood mononuclear cells (... von Molinero, Luciana, Guan, Xiangnan, Deurloo, Regula, Gozlan, Yosi, Sharim, Hila, Emens, Leisha A., Cameron, David A., Schmid, Peter, Miles, David, Adams, Sylvia, Chui, Stephen Y., Mariathasan, Sanjeev, O'Shaughnessy, Joyce, Andre, Fabrice, Loi, Sherene

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DSP107, a Novel Bi-Functional Fusion Protein That Combines Inhibition of CD47 with Targeted Activation of 4-1BB to Trigger Innate and Adaptive Anticancer Immune Responses von Cendrowicz, Ewa, Jacob, Lisa, Greenwald, Shirley, Tamir, Ami, Gozlan, Yosi, Huls, Gerwin, Foley-Comer, Adam, Pereg, Yaron, Chajut, Ayelet, Peled, Amnon, Bremer, Edwin

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Abstract CT204: High cytotoxic T-cell or polymorphonuclear cell infiltrates in the tumor microenvironment correlate with responses to BL8040 plus pembrolizumab combination therapy... von Barreto, Carmelia M. Noia, Ledesma, Debora A., Gite, Swati, Solis, Luisa M., Jiang, Mei, Pandurengan, Renganayaki K., Wolff, Robert, Javle, Milind, Pant, Shubham, Varadhachary, Gauri, Shroff, Rachna, Vainstein-Haras, Abi, Sorani, Ella, Lustig, Tzipora M., Kashtan, Osnat, Gozlan, Yosi, Townson, Steven M., Fahey, Jeanne M., Yao, James, Wistuba, Ignacio I., Overman, Michael, Fogelman, David, Parra, Edwin R.

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CTLA4-FasL, the Hexameric Targeted FasL Fusion Protein, As Potential Novel Treatment for DLBCL von Aronin, Alexandra, Ben Gigi-Tamir, Liat, Makdasi, Efi, Amsili, Shira, Ben David, Shlomi, Avraham, Ortal, Sagiv, Yehudith Jitka, Gozlan, Yosi Meir, Shani, Noam, Dranitzki Elhalel, Michal

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Toxicology and Pharmacokinetic Studies in Mice and Nonhuman Primates of the Nontoxic, Efficient, Targeted Hexameric FasL: CTLA4-FasL von Makdasi, Efi, Amsili, Shira, Aronin, Alexandra, Prigozhina, Tatyana B, Tzdaka, Kobi, Gozlan, Yosi Meir, Ben Gigi-Tamir, Liat, Sagiv, Jitka Yehudith, Shkedy, Fanny, Shani, Noam, Tykocinski, Mark L, Dranitzki Elhalel, Michal

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DSP107 combines inhibition of CD47/SIRP[alpha] axis with activation of 4-1BB to trigger anticancer immunity von Zorde-Khvalevsky, Elina, Kahn, Roy, Amsili, Shira, Tamir, Liat, Vlaming, Martijn, Chajut, Ayelet, Avichzer, Jasmine, Aronin, Alexandra, Tamir, Ami, Tabakman, Rinat, Huls, Gerwin, Gozlan, Yosi, Pereg, Yaron, Ghantous, Lucy, Cendrowicz, Ewa, Pecker, Iris, Bremer, Edwin, Jacob, Lisa, van Meerten, Tom, Foley-Comer, Adam, Greenwald, Shirley, Dranitzki, Michal Elhalel, Peled, Amnon

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Abstract 5583: SUV39H1 disruption enhances the persistence and anti-tumor efficacy of CD28-costimulated human CAR T cells von Jain, Nayan, Zhao, Zeguo, Koche, Richard, Gozlan, Yosi, Brocks, David, Raveh-Sadka, Tali, Wells, Danny, Dobrin, Anton, Shi, Yuzhe, Lopez, Michael, Gunset, Gertrude, Sadelain, Michel

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“First AID” for T cell adoptive transfer: TCR affinity maturation by somatic hypermutation von Gozlan, Yosi M, Tzehoval, Esther, Eisenbach, Lea

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Abstract A076: DSP107—a novel SIRPα-4-1BBL dual signaling protein (DSP) for cancer immunotherapy von Gozlan, Yosi M., Hilgendorf, Susan, Aronin, Alexandra, Sagiv, Yehudith, Ben-gigi-Tamir, Liat, Amsili, Shira, Tamir, Ami, Pecker, Iris, Greenwald, Shirley, Chajut, Ayelet, Foley-Comer, Adam, Pereg, Yaron, Peled, Amnon, Dranitzki-Elhalel, Michal, Bremer, Edwin

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"First AID" for T cell adoptive transfer: TCR affinity maturation by somatic hypermutation von Yosi, Gozlan, Zoya, Alteber, Meir, Azulay, Adi, Sharbi Yunger, Esther, Tzehoval, Lea, Eisenbach

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Production of lacZ inducible T cell hybridoma specific for human and mouse gp10025-33 peptides von Gal, Cafri, Adi, Sharbi-Yunger, Esther, Tzehoval, Zoya, Alteber, Meir, Azulay, Yosi, Gozlan, Lea, Eisenbach

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The role of IFITM genes in the pathogenesis of the gastro-intestinal tract von Zoya, Alteber, Meir, Azulay, Yosi, Gozlan, Adi, Sharbi-Yunger, Esther, Tzehoval, Lea, Eisenbach

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T cell Tolerance as Function of Tumor Progression von Meir, Azulay, Yosi, Gozlan, Zoya, Alteber, Adi, Shrbi Younger, Esther, Tzehoval, Lea, Eisenbach

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AFFINITY MATURATED T CELL RECEPTORS AND USE THEREOF von GOZLAN, Yosi, EISENBACH, Rachel Lea, TZEHOVAL, Esther

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