Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector von Bowles, Dawn E, McPhee, Scott WJ, Li, Chengwen, Gray, Steven J, Samulski, Jade J, Camp, Angelique S, Li, Juan, Wang, Bing, Monahan, Paul E, Rabinowitz, Joseph E, Grieger, Joshua C, Govindasamy, Lakshmanan, Agbandje-McKenna, Mavis, Xiao, Xiao, Samulski, R Jude

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Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses von Zhong, Li, Li, Baozheng, Mah, Cathryn S, Govindasamy, Lakshmanan, Agbandje-McKenna, Mavis, Cooper, Mario, Herzog, Roland W, Zolotukhin, Irene, Warrington, Kenneth H. Jr, Weigel-Van Aken, Kirsten A, Hobbs, Jacqueline A, Zolotukhin, Sergei, Muzyczka, Nicholas, Srivastava, Arun

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Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold? von Aslanidi, George V, Rivers, Angela E, Ortiz, Luis, Song, Liujiang, Ling, Chen, Govindasamy, Lakshmanan, Van Vliet, Kim, Tan, Mengqun, Agbandje-McKenna, Mavis, Srivastava, Arun

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Structural Insights into Adeno-Associated Virus Serotype 5 von Govindasamy, Lakshmanan, DiMattia, Michael A, Gurda, Brittney L, Halder, Sujata, McKenna, Robert, Chiorini, John A, Muzyczka, Nicholas, Zolotukhin, Sergei, Agbandje-McKenna, Mavis

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Single Amino Acid Changes Can Influence Titer, Heparin Binding, and Tissue Tropism in Different Adeno-Associated Virus Serotypes von ZHIJIAN WU, ASOKAN, Aravind, GRIEGER, Joshua C, GOVINDASAMY, Lakshmanan, AGBANDJE-MCKENNA, Mavis, SAMULSKI, R. Jude

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Structural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6 von Ng, Robert, Govindasamy, Lakshmanan, Gurda, Brittney L, McKenna, Robert, Kozyreva, Olga G, Samulski, R Jude, Parent, Kristin N, Baker, Timothy S, Agbandje-McKenna, Mavis

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Structurally Mapping the Diverse Phenotype of Adeno-Associated Virus Serotype 4 von GOVINDASAMY, Lakshmanan, PADRON, Eric, MCKENNA, Robert, MUZYCZKA, Nicholas, KALUDOV, Nikola, CHIORINI, John A, AGBANDJE-MCKENNA, Mavis

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Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression von Zhong, Li, Li, Baozheng, Jayandharan, Giridhararao, Mah, Cathryn S, Govindasamy, Lakshmanan, Agbandje-McKenna, Mavis, Herzog, Roland W, Weigel-Van Aken, Kirsten A, Hobbs, Jacqueline A, Zolotukhin, Sergei, Muzyczka, Nicholas, Srivastava, Arun

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Adeno-Associated Virus Type 2 Contains an Integrin α5β1 Binding Domain Essential for Viral Cell Entry von ASOKAN, Aravind, HAMRA, Julie B, GOVINDASAMY, Lakshmanan, AGBANDJE-MCKENNA, Mavis, SAMULSKI, Richard J

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A Dual Role of EGFR Protein Tyrosine Kinase Signaling in Ubiquitination of AAV2 Capsids and Viral Second-strand DNA Synthesis von Zhong, Li, Zhao, Weihong, Wu, Jianqing, Li, Baozheng, Zolotukhin, Sergei, Govindasamy, Lakshmanan, Agbandje-McKenna, Mavis, Srivastava, Arun

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Structural Characterization of H-1 Parvovirus: Comparison of Infectious Virions to Empty Capsids von Halder, Sujata, Nam, Hyun-Joo, Govindasamy, Lakshmanan, Vogel, Michèle, Dinsart, Christiane, Salomé, Nathalie, McKenna, Robert, Agbandje-McKenna, Mavis

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Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II von Fisher, Zoë, Hernandez Prada, Jose A, Tu, Chingkuang, Duda, David, Yoshioka, Craig, An, Haiqian, Govindasamy, Lakshmanan, Silverman, David N, McKenna, Robert

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Molecular Characterization of the Heparin-Dependent Transduction Domain on the Capsid of a Novel Adeno-Associated Virus Isolate, AAV(VR-942) von SCHMIDT, Michael, GOVINDASAMY, Lakshmanan, AFIONE, Sandra, KALUDOV, Nick, AGBANDJE-MCKENNA, Mavis, CHIORINI, John A

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Surface Loop Dynamics in Adeno-Associated Virus Capsid Assembly von DIPRIMIO, Nina, ASOKAN, Aravind, GOVINDASAMY, Lakshmanan, AGBANDJE-MCKENNA, Mavis, JUDE SAMULSKI, R

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Structure of Adeno-Associated Virus Type 4 von PADRON, Eric, BOWMAN, Valorie, AGBANDJE-MCKENNA, Mavis, KALUDOV, Nikola, GOVINDASAMY, Lakshmanan, LEVY, Hazel, NICK, Phillip, MCKENNA, Robert, MUZYCZKA, Nicholas, CHIORINI, John A, BAKER, Timothy S

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Structures of Host Range-Controlling Regions of the Capsids of Canine and Feline Parvoviruses and Mutants von Govindasamy, Lakshmanan, Hueffer, Karsten, Parrish, Colin R, Agbandje-McKenna, Mavis

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Structural Determinants of Tissue Tropism and In Vivo Pathogenicity for the Parvovirus Minute Virus of Mice von KONTOU, Maria, GOVINDASAMY, Lakshmanan, AGBANDJE-MCKENNA, Mavis, NAM, Hyun-Joo, BRYANT, Nathan, LLAMAS-SAIZ, Antonio L, FOCES-FOCES, Concepcion, HERNANDO, Eva, RUBIO, Mari-Paz, MCKENNA, Robert, ALMENDRAL, José M

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Analysis of HIV-1 CRF_01 A/E Protease Inhibitor Resistance:  Structural Determinants for Maintaining Sensitivity and Developing Resistance to Atazanavir von Clemente, José C, Coman, Roxana M, Thiaville, Michele M, Janka, Linda K, Jeung, Jennifer A, Nukoolkarn, Sarawut, Govindasamy, Lakshmanan, Agbandje-McKenna, Mavis, McKenna, Robert, Leelamanit, Wichet, Goodenow, Maureen M, Dunn, Ben M

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Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease von Clemente, José C, Moose, Rebecca E, Hemrajani, Reena, Whitford, Lisa R. S, Govindasamy, Lakshmanan, Reutzel, Robbie, McKenna, Robert, Agbandje-McKenna, Mavis, Goodenow, Maureen M, Dunn, Ben M

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Engineering Liver-detargeted AAV9 Vectors for Cardiac and Musculoskeletal Gene Transfer von Pulicherla, Nagesh, Shen, Shen, Yadav, Swati, Debbink, Kari, Govindasamy, Lakshmanan, Agbandje-McKenna, Mavis, Asokan, Aravind

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