A call for transparent reporting to optimize the predictive value of preclinical research von Landis, Story C., Amara, Susan G., Asadullah, Khusru, Austin, Chris P., Blumenstein, Robi, Bradley, Eileen W., Crystal, Ronald G., Darnell, Robert B., Ferrante, Robert J., Fillit, Howard, Finkelstein, Robert, Fisher, Marc, Gendelman, Howard E., Golub, Robert M., Goudreau, John L., Gross, Robert A., Gubitz, Amelie K., Hesterlee, Sharon E., Howells, David W., Huguenard, John, Kelner, Katrina, Koroshetz, Walter, Krainc, Dimitri, Lazic, Stanley E., Levine, Michael S., Macleod, Malcolm R., McCall, John M., Moxley III, Richard T., Narasimhan, Kalyani, Noble, Linda J., Perrin, Steve, Porter, John D., Steward, Oswald, Unger, Ellis, Utz, Ursula, Silberberg, Shai D.

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Inosine to Increase Serum and Cerebrospinal Fluid Urate in Parkinson Disease: A Randomized Clinical Trial von Schwarzschild, Michael A, Ascherio, Alberto, Beal, M. Flint, Cudkowicz, Merit E, Curhan, Gary C, Hare, Joshua M, Hooper, D. Craig, Kieburtz, Karl D, Macklin, Eric A, Oakes, David, Rudolph, Alice, Shoulson, Ira, Tennis, Marsha K, Espay, Alberto J, Gartner, Maureen, Hung, Albert, Bwala, Grace, Lenehan, Richard, Encarnacion, Elmyra, Ainslie, Melissa, Castillo, Richard, Togasaki, Daniel, Barles, Gina, Friedman, Joseph H, Niles, Lisa, Carter, Julie H, Murray, Megan, Goetz, Christopher G, Jaglin, Jeana, Ahmed, Anwar, Russell, David S, Cotto, Candace, Goudreau, John L, Russell, Doozie, Parashos, Sotirios Andreas, Ede, Patricia, Saint-Hilaire, Marie H, Thomas, Cathi-Ann, James, Raymond, Stacy, Mark A, Johnson, Julia, Gauger, Lisa, Antonelle de Marcaida, J, Thurlow, Sheila, Isaacson, Stuart H, Carvajal, Lisbeth, Rao, Jayaraman, Cook, Maureen, Hope-Porche, Charlise, McClurg, Lauren, Grasso, Daniela L, Logan, Robert, Orme, Constance, Ross, Tori, Brocht, Alicia F. D, Constantinescu, Radu, Sharma, Saloni, Venuto, Charles, Weber, Joseph, Eaton, Ken

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Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial von Schwarzschild, Michael A, Macklin, Eric A, Bakshi, Rachit, Battacharyya, Shamik, Logan, Robert, Espay, Alberto J, Hung, Albert Y, Bwala, Grace, Goetz, Christopher G, Russell, David S, Goudreau, John L, Parashos, Sotirios A, Saint-Hilaire, Marie H, Rudolph, Alice, Hare, Joshua M, Curhan, Gary C, Ascherio, Alberto

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BDNF rs10501087, rs1491850 and rs11030094 polymorphisms associated with delayed progression in early-stage Parkinson's disease von Fischer, D Luke, Auinger, Peggy, Goudreau, John L, Paumier, Katrina L, Cole-Strauss, Allyson, Kemp, Christopher J, Lipton, Jack W, Sortwell, Caryl E

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BDNF rs6265 Variant Alters Outcomes with Levodopa in Early-Stage Parkinson’s Disease von Fischer, D. Luke, Auinger, Peggy, Goudreau, John L., Cole-Strauss, Allyson, Kieburtz, Karl, Elm, Jordan J., Hacker, Mallory L., Charles, P. David, Lipton, Jack W., Pickut, Barbara A., Sortwell, Caryl E.

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Heterozygous VPS13A and PARK2 Mutations in a Patient with Parkinsonism and Seizures von Mitchell, Steven D., Albin, Roger L., Dauer, William T., Goudreau, John L., Sidiropoulos, Christos

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Activation of autophagy through modulation of 5'-AMP-activated protein kinase protects pancreatic beta-cells from high glucose von Han, Diana, Yang, Byungho, Olson, L Karl, Greenstein, Alexander, Baek, Seung-Hoon, Claycombe, Kate J, Goudreau, John L, Yu, Seong-Woon, Kim, Eun-Kyoung

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Restoring pars intermedia dopamine concentrations and tyrosine hydroxylase expression levels with pergolide: evidence from horses with pituitary pars intermedia dysfunction von Fortin, Jessica S, Benskey, Matthew J, Lookingland, Keith J, Patterson, Jon S, Howey, Erin B, Goudreau, John L, Schott, 2nd, Harold C

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Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease von Fischer, D. Luke, Auinger, Peggy, Goudreau, John L., Paumier, Katrina L., Cole-Strauss, Allyson, Kemp, Christopher J., Lipton, Jack W., Sortwell, Caryl E.

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Metabolism of Dopamine in Nucleus Accumbens Astrocytes Is Preserved in Aged Mice Exposed to MPTP von Winner, Brittany M, Zhang, Harue, Farthing, McKenzie M, Karchalla, Lalitha M, Lookingland, Keith J, Goudreau, John L

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Autophagic Death of Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal von Yu, Seong‐Woon, Baek, Seung‐Hoon, Brennan, Ryan T., Bradley, Christopher J., Park, Se Kyong, Lee, Yoon Sun, Jun, Eun Jung, Lookingland, Keith J., Kim, Eun‐Kyoung, Lee, Heuiran, Goudreau, John L., Kim, Seong Who

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FosB and ΔFosB expression in brain regions containing differentially susceptible dopamine neurons following acute neurotoxicant exposure von Patterson, Joseph R, Kim, Elizabeth J, Goudreau, John L, Lookingland, Keith J

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Choice of dopaminergic therapy among early, mild Parkinson disease subjects in North America von Goudreau, John L, Pérez, Adriana, Aminoff, Michael J, Boyd, James T, Burau, Keith D, Christine, Chadwick W, Leehey, Maureen, Morgan, John C

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Asiatic acid, a pentacyclic triterpene from Centella asiatica, is neuroprotective in a mouse model of focal cerebral ischemia von Krishnamurthy, Rajanikant G., Senut, Marie-Claude, Zemke, Daniel, Min, Jiangyong, Frenkel, Mark B., Greenberg, Eric J., Yu, Seong-Woon, Ahn, Nick, Goudreau, John, Kassab, Mounzer, Panickar, Kiran S., Majid, Arshad

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Alpha‐Synuclein induces hyperphosphorylation of Tau in the MPTP model of Parkinsonism von Duka, Tetyana, Rusnak, Milan, Drolet, Robert E., Duka, Valeriy, Wersinger, Christophe, Goudreau, John L., Sidhu, Anita

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Comparison of the structure, function and autophagic maintenance of mitochondria in nigrostriatal and tuberoinfundibular dopamine neurons von Hawong, Hae-young, Patterson, Joseph R, Winner, Brittany M, Goudreau, John L, Lookingland, Keith J

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Asiatic Acid Attenuates Infarct Volume, Mitochondrial Dysfunction, and Matrix Metalloproteinase-9 Induction After Focal Cerebral Ischemia von KI YONG LEE, BAE, Ok-Nam, GOUDREAU, John, KASSAB, Mounzer, MAJID, Arshad, SERFOZO, Kelsey, HEJABIAN, Siamk, MOUSSA, Ahmad, REEVES, Mathew, RUMBEIHA, Wilson, FITZGERALD, Scott D, STEIN, Gary, BAEK, Seung-Hoon

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Methylmercury impairs canonical dopamine metabolism in rat undifferentiated pheochromocytoma (PC12) cells by indirect inhibition of aldehyde dehydrogenase von Tiernan, Chelsea T, Edwin, Ethan A, Hawong, Hae-Young, Ríos-Cabanillas, Mónica, Goudreau, John L, Atchison, William D, Lookingland, Keith J

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Sustained resistance to acute MPTP toxicity by hypothalamic dopamine neurons following chronic neurotoxicant exposure is associated with sustained up-regulation of parkin protein von Benskey, Matthew, Lee, Ki Yong, Parikh, Kevin, Lookingland, Keith J., Goudreau, John L.

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The role of de novo catecholamine synthesis in mediating methylmercury-induced vesicular dopamine release from rat pheochromocytoma (PC12) cells von Tiernan, Chelsea T, Edwin, Ethan A, Goudreau, John L, Atchison, William D, Lookingland, Keith J

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