miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors von Moskwa, Patryk, Buffa, Francesca M., Pan, Yunfeng, Panchakshari, Rohit, Gottipati, Ponnari, Muschel, Ruth J., Beech, John, Kulshrestha, Ritu, Abdelmohsen, Kotb, Weinstock, David M., Gorospe, Myriam, Harris, Adrian L., Helleday, Thomas, Chowdhury, Dipanjan

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Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination―Defective Cells von GOTTIPATI, Ponnari, VISCHIONI, Barbara, SCHULTZ, Niklas, SOLOMONS, Joyce, BRYANT, Helen E, DJUREINOVIC, Tatjana, ISSAEVA, Natalia, SLEETH, Kate, SHARMA, Ricky A, HELLEDAY, Thomas

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Contextual Synthetic Lethality of Cancer Cell Kill Based on the Tumor Microenvironment von CHAN, Norman, PIRES, Isabel M, HAMMOND, Ester M, BRISTOW, Robert G, BENCOKOVA, Zuzana, COACKLEY, Carla, LUOTO, Kaisa R, BHOGAL, Nirmal, LAKSHMAN, Minalini, GOTTIPATI, Ponnari, OLIVER, F. Javier, HELLEDAY, Thomas

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Transcription-Associated Recombination Is Dependent on Replication in Mammalian Cells von Gottipati, Ponnari, Cassel, Tobias N., Savolainen, Linda, Helleday, Thomas

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Transcription inhibition by DRB potentiates recombinational repair of UV lesions in mammalian cells von Stoimenov, Ivaylo, Schultz, Niklas, Gottipati, Ponnari, Helleday, Thomas

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Transcription-associated recombination in eukaryotes: link between transcription, replication and recombination von Gottipati, Ponnari, Helleday, Thomas

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6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance von ISSAEVA, Natalia, THOMAS, Huw D, CHATZAKOS, Vicky, MULLIGAN, Evan A, LUNDIN, Cecilia, GUBANOVA, Evgenia, KERSBERGEN, Ariena, HARRIS, Adrian L, SHARMA, Ricky A, ROTTENBERG, Sven, CURTIN, Nicola J, HELLEDAY, Thomas, DJURENOVIC, Tatjana, JASPERS, Janneke E, STOIMENOV, Ivaylo, KYLE, Suzanne, PEDLEY, Nicholas, GOTTIPATI, Ponnari, ZUR, Rafal, SLEETH, Kate

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miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors von Moskwa, Patryk, Buffa, Francesca M., Pan, Yunfeng, Panchakshari, Rohit, Gottipati, Ponnari, Muschel, Ruth J., Beech, John, Kulshrestha, Ritu, Abdelmohsen, Kotb, Weinstock, David M., Gorospe, Myriam, Harris, Adrian L., Helleday, Thomas, Chowdhury, Dipanjan

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miR-182-mediated down-regulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors von Moskwa, Patryk, Buffa, Francesca M., Pan, Yunfeng, Panchakshari, Rohit, Gottipati, Ponnari, Muschel, Ruth J, Beech, John, Kulshrestha, Ritu, Abdelmohsen, Kotb, Weinstock, David M., Gorospe, Myriam, Harris, Adrian L., Helleday, Thomas, Chowdhury, Dipanjan

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Abstract A115: Contextual synthetic lethality: Repair-deficient hypoxic tumor cells are sensitized to poly(ADP-ribose) polymerase (PARP) inhibition von Chan, Norman, Pires, Isabel M., Bencokova, Zuzana, Coackley, Carla, Bhogal, Nirmal, Lakshman, Minalini, Gottipati, Ponnari, Oliver, F Javier, Helleday, Thomas, Hammond, Ester M., Bristow, Robert G.

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