EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma von Gorthi, Aparna, Romero, July Carolina, Loranc, Eva, Cao, Lin, Lawrence, Liesl A., Goodale, Elicia, Iniguez, Amanda Balboni, Bernard, Xavier, Masamsetti, V. Pragathi, Roston, Sydney, Lawlor, Elizabeth R., Toretsky, Jeffrey A., Stegmaier, Kimberly, Lessnick, Stephen L., Chen, Yidong, Bishop, Alexander J. R.

Volltext

Predicting drug response of tumors from integrated genomic profiles by deep neural networks von Chiu, Yu-Chiao, Chen, Hung-I Harry, Zhang, Tinghe, Zhang, Songyao, Gorthi, Aparna, Wang, Li-Ju, Huang, Yufei, Chen, Yidong

Volltext

Abstract 4401: Implications of STAG2 loss in Ewing sarcoma von Gorthi, Aparna

Volltext

Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit von de Araujo, Patricia Rosa, Gorthi, Aparna, da Silva, Acarizia E., Tonapi, Sonal S., Vo, Dat T., Burns, Suzanne C., Qiao, Mei, Uren, Philip J., Yuan, Zhi-Min, Bishop, Alexander J.R., Penalva, Luiz O.F.

Volltext

Ewing sarcoma fusion oncogene: At the crossroads of transcription and DNA damage response von Gorthi, Aparna, Bishop, Alexander J. R.

Volltext

RNA helicase DDX3 regulates RAD51 localization and DNA damage repair in Ewing sarcoma von Randolph, Matthew E., Afifi, Marwa, Gorthi, Aparna, Weil, Rachel, Wilky, Breelyn A., Weinreb, Joshua, Ciero, Paul, Hoeve, Natalie ter, van Diest, Paul J., Raman, Venu, Bishop, Alexander J.R., Loeb, David M.

Volltext

Scaffold Architecture and Matrix Strain Modulate Mesenchymal Cell and Microvascular Growth and Development in a Time Dependent Manner von Chiou, Gennifer, Jui, Elysa, Rhea, Allison C., Gorthi, Aparna, Miar, Solaleh, Acosta, Francisca M., Perez, Cynthia, Suhail, Yasir, Kshitiz, Chen, Yidong, Ong, Joo L., Bizios, Rena, Rathbone, Christopher, Guda, Teja

Volltext

Correction to: Predicting drug response of tumors from integrated genomic profiles by deep neural networks von Chiu, Yu-Chiao, Chen, Hung-I Harry, Zhang, Tinghe, Zhang, Songyao, Gorthi, Aparna, Wang, Li-Ju, Huang, Yufei, Chen, Yidong

Volltext

The landscape of therapeutic vulnerabilities in EGFR inhibitor osimertinib drug tolerant persister cells von Criscione, Steven W., Martin, Matthew J., Oien, Derek B., Gorthi, Aparna, Miragaia, Ricardo J., Zhang, Jingwen, Chen, Huawei, Karl, Daniel L., Mendler, Kerrin, Markovets, Aleksandra, Gagrica, Sladjana, Delpuech, Oona, Dry, Jonathan R., Grondine, Michael, Hattersley, Maureen M., Urosevic, Jelena, Floc’h, Nicolas, Drew, Lisa, Yao, Yi, Smith, Paul D.

Volltext

ATR suppresses endogenous DNA damage and allows completion of homologous recombination repair von Brown, Adam D, Sager, Brian W, Gorthi, Aparna, Tonapi, Sonal S, Brown, Eric J, Bishop, Alexander J R

Volltext

Nucleolar RNA polymerase II drives ribosome biogenesis von Abraham, Karan J., Khosraviani, Negin, Chan, Janet N. Y., Gorthi, Aparna, Samman, Anas, Zhao, Dorothy Y., Wang, Miling, Bokros, Michael, Vidya, Elva, Ostrowski, Lauren A., Oshidari, Roxanne, Pietrobon, Violena, Patel, Parasvi S., Algouneh, Arash, Singhania, Rajat, Liu, Yupeng, Yerlici, V. Talya, De Carvalho, Daniel D., Ohh, Michael, Dickson, Brendan C., Hakem, Razq, Greenblatt, Jack F., Lee, Stephen, Bishop, Alexander J. R., Mekhail, Karim

Volltext

Abstract P5-10-03: Mutant p53 and ERK1/2 MAPK cooperate with the production of TNBC inflammatory secretome von das Neves, Raquel Nascimento, Gorthi, Aparna, Bishop, Alexander James Roy, Filho, Alfeu Zanotto

Volltext

Deep learning of pharmacogenomics resources: moving towards precision oncology von Chiu, Yu-Chiao, Chen, Hung-I Harry, Gorthi, Aparna, Mostavi, Milad, Zheng, Siyuan, Huang, Yufei, Chen, Yidong

Volltext

The molecular landscape of ETMR at diagnosis and relapse von Lambo, Sander, Gröbner, Susanne N., Rausch, Tobias, Waszak, Sebastian M., Schmidt, Christin, Gorthi, Aparna, Romero, July Carolina, Mauermann, Monika, Brabetz, Sebastian, Krausert, Sonja, Buchhalter, Ivo, Koster, Jan, Zwijnenburg, Danny A., Sill, Martin, Hübner, Jens-Martin, Mack, Norman, Schwalm, Benjamin, Ryzhova, Marina, Hovestadt, Volker, Papillon-Cavanagh, Simon, Chan, Jennifer A., Landgraf, Pablo, Ho, Ben, Milde, Till, Witt, Olaf, Ecker, Jonas, Sahm, Felix, Sumerauer, David, Ellison, David W., Orr, Brent A., Darabi, Anna, Haberler, Christine, Figarella-Branger, Dominique, Wesseling, Pieter, Schittenhelm, Jens, Remke, Marc, Taylor, Michael D., Gil-da-Costa, Maria J., Łastowska, Maria, Grajkowska, Wiesława, Hasselblatt, Martin, Hauser, Peter, Pietsch, Torsten, Uro-Coste, Emmanuelle, Bourdeaut, Franck, Masliah-Planchon, Julien, Rigau, Valérie, Alexandrescu, Sanda, Wolf, Stephan, Li, Xiao-Nan, Schüller, Ulrich, Snuderl, Matija, Karajannis, Matthias A., Giangaspero, Felice, Jabado, Nada, von Deimling, Andreas, Jones, David T. W., Korbel, Jan O., von Hoff, Katja, Lichter, Peter, Huang, Annie, Bishop, Alexander J. R., Pfister, Stefan M., Korshunov, Andrey, Kool, Marcel

Volltext

Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA von Pan, Hai, Jin, Miao, Ghadiyaram, Ashwin, Kaur, Parminder, Miller, Henry E, Ta, Hai Minh, Liu, Ming, Fan, Yanlin, Mahn, Chelsea, Gorthi, Aparna, You, Changjiang, Piehler, Jacob, Riehn, Robert, Bishop, Alexander J R, Tao, Yizhi Jane, Wang, Hong

Volltext

Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis von Zanotto-Filho, Alfeu, Masamsetti, V Pragathi, Loranc, Eva, Tonapi, Sonal S, Gorthi, Aparna, Bernard, Xavier, Gonçalves, Rosângela Mayer, Moreira, José C F, Chen, Yidong, Bishop, Alexander J R

Volltext

Cohesin SA2 is a sequence-independent DNA-binding protein that recognizes DNA replication and repair intermediates von Countryman, Preston, Fan, Yanlin, Gorthi, Aparna, Pan, Hai, Strickland, Evelyn, Kaur, Parminder, Wang, Xuechun, Lin, Jiangguo, Lei, Xiaoying, White, Christian, You, Changjiang, Wirth, Nicolas, Tessmer, Ingrid, Piehler, Jacob, Riehn, Robert, Bishop, Alexander J.R., Tao, Yizhi Jane, Wang, Hong

Volltext

Cohesin SA2 and EWSR1 in R-Loop Regulation von Wang, Hong, Ghadiyaram, Ashwin, Pan, Hai, Fan, Yanlin, Kaur, Parminder, Gorthi, Aparna, Riehn, Robert, Bishop, Alexander J.R., Jane Tao, Yizhi

Volltext

Determination of tumor PSMA expression and lutetium-PSMA response in men with prostate cancer using a novel epigenomic liquid biopsy platform von Ravi, Praful, D'Ipppolito, Anthony, Wurster, Jenna, Kramer, Nicole, Painter, Corrie, Gorthi, Aparna, Eaton, Matthew, Barrett, Carl, Jacene, Heather, Berchuck, Jacob

Volltext

Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis von Rajamanickam, Subapriya, Panneerdoss, Subbarayalu, Gorthi, Aparna, Timilsina, Santosh, Onyeagucha, Benjamin, Kovalskyy, Dmytro, Ivanov, Dmitri, Hanes, Martha A, Vadlamudi, Ratna K, Chen, Yidong, Bishop, Alexander J, Arbiser, Jack L, Rao, Manjeet K

Volltext