Ruxolitinib in combination with prednisone and nilotinib exhibit synergistic effects in human cells lines and primary cells from myeloproliferative neoplasms von Cortés, Alicia Arenas, Diaz, Rosa Ayala, Hernández-Campo, Pilar, Gorrochategui, Julián, Primo, Daniel, Robles, Alicia, Morales, María Luz, Ballesteros, Joan, Rapado, Inmaculada, Gallardo, Miguel, Linares, María, Martínez-López, Joaquín

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Screening of antimicrobial activities in red, green and brown macroalgae from Gran Canaria (Canary Islands, Spain) von González del Val, A, Platas, G, Basilio, A, Cabello, A, Gorrochategui, J, Suay, I, Vicente, F, Portillo, E, Jiménez del Río, M, Reina, G G, Peláez, F

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Screening of basidiomycetes for antimicrobial activities von SUAY, Inmaculada, ARENAL, Francisco, PELAEZ, Fernando, VICENTE, M. Francisca, ASENSIO, Francisco J, BASILIO, Angela, CABELLO, M. Angeles, DIEZ, M. Teresa, GARCIA, Juan B, GONZALEZ DEL VAL, Antonio, GORROCHATEGUI, Julian, HERNANDEZ, Pilar

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Improving the prediction of acute myeloid leukaemia outcomes by complementing mutational profiling with ex vivo chemosensitivity von Onecha, Esther, Ruiz‐Heredia, Yanira, Martínez‐Cuadrón, David, Barragán, Eva, Martinez‐Sanchez, Pilar, Linares, María, Rapado, Inmaculada, Perez‐Oteyza, Jaime, Magro, Elena, Herrera, Pilar, Rojas, José Luis, Gorrochategui, Julián, Villoria, Jesús, Boluda, Blanca, Sargas, Claudia, Ballesteros, Joan, Montesinos, Pau, Martínez‐López, Joaquín, Ayala, Rosa

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A precision medicine test predicts clinical response after idarubicin and cytarabine induction therapy in AML patients von Martínez-Cuadrón, David, Gil, Cristina, Serrano, Josefina, Rodríguez, Gabriela, Pérez-Oteyza, Jaime, García-Boyero, Raimundo, Jiménez-Bravo, Santiago, Vives, Susana, Vidriales, María Belén, Lavilla, Esperanza, Pérez-Simón, José A., Tormo, Mar, Colorado, Mercedes, Bergua, Juan, López, Juan A., Herrera, Pilar, Hernández-Campo, Pilar, Gorrochategui, Julián, Primo, Daniel, Rojas, Jose Luis, Villoria, Jesús, Moscardó, Federico, Troconiz, Iñaki, Linares Gómez, María, Martínez-López, Joaquín, Ballesteros, Joan, Sanz, Miguel, Montesinos, Pau

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Clinical Correlation of a Precision Medicine Test with Treatment Outcome in Acute Myeloid Leukemia Patients von Zhu, Hong-Hu, Ji, Min, Ji, Chunyan, Wang, Chongwu, Ge, Yaqiong, Zhou, Xiaoping, Gorrochategui, Julian, Primo, Daniel, Ballesteros, Joan, Li, Li, Martinez-López, Joaquin

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Putative Predictors of Response to WU-NK-101, an Allogeneic, Enhanced Memory (ML) Natural Killer (NK) Cell Therapy Product, for Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AM... von Rutella, Sergio, Cashen, Amanda F., Muth, John, Mathyer, Mary Elizabeth, Carter, Alun James, Tumala, Brunda, Arthur, Laura, Magee, Kristann, Comune Pennacchi, Paula, Gorrochategui, Julian, Petit, Vincent, Primo, Daniel, Blanchard, Dominique, Kiebish, Michael, Bhatnagar, Nupur, Boocock, David, Vadakekolathu, Jayakumar, Cooper, Matthew L, Berrien-Elliott, Melissa M., Davidson-Moncada, Jan K, Fehniger, Todd A.

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Abstract B012: A novel in vitro approach elucidates a new mode of cytotoxic action of bispecific antibodies on hematologic malignancies von Primo, Daniel, Hernandez, Pilar, Gorrochategui, Julian, Vicente, Maria L., Martinez-Cuadron, David, Montesinos, Pau, Mártinez-López, Joaquin, Ballesteros, Joan

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Biomarker-Driven Phase Ib Clinical Trial of OPB-111077 in Acute Myeloid Leukemia Increases Overall Response Rates von Martinez-Lopez, Joaquin, Montesinos, Pau, Martinez Sanchez, Pilar, Gorrochategui, Julian, Rojas, Jose Luis, Primo, Daniel, Bergua, Juan-Miguel, Ayala, Rosa M.M., Calbacho, Maria, López-Muñoz, Nieves, Acuña, Evelyn, Pérez-Simón, Jose Antonio, de la Fuente, Adolfo, Perez De Oteyza, Jaime, Rodríguez-Veiga, Rebeca, Boluda, Blanca, Cano, Isabel, Ballesteros, Joan

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Abstract 22: A new precision medicine test to guide personalized treatments decision for acute myeloid leukemia patients von Ballesteros, Joan, Montesinos, Pau, Martinez-Cuadron, David, Martinez-Lopez, Joaquin, Gorrochategui, Julian, Rojas, Jose Luis, Gomez, Cristina, Hernandez, Pilar, Robles, Alicia

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Isolation and structure elucidation of coleophomones A and B, novel inhibitors of bacterial cell wall transglycosylase von Wilson, Kenneth E., Tsou, Nancy N., Guan, Ziqiang, Ruby, Carolyn L., Pelaez, Fernando, Gorrochategui, Julian, Vicente, Francisca, Onishi, H.Russell

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Drug Discovery Testing Compounds in Patient Samples by Automated Flow Cytometry von Hernández, Pilar, Gorrochategui, Julián, Primo, Daniel, Robles, Alicia, Rojas, José Luis, Espinosa, Ana Belén, Gómez, Cristina, Martínez-López, Joaquín, Bennett, Teresa A., Ballesteros, Joan

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Bispecific Antibodies on Hematological Malignancies: A Novel Mechanism of Action That May Contribute to Therapeutic Efficacy von Primo, Daniel, Hernandez, Pilar, de la Serna, Javier, Ribera, Josep-Maria, Vives, Susana, Bergua, Juan, Perez de Oteyza, Jaime, Serrano, Josefina, Gorrochategui, Julian, María Luisa, Vicente, Martínez-Cuadron, David, Montesinos, Pau, Martinez Lopez, Joaquin, Ballesteros, Joan

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Ruxolitinib in Combination with Nilotinib and Prednisolone, a New Synergistic Approach to Treat Myelofibrosis von Arenas, Alicia, Hernandez-Campo, Pilar, Gorrochategui, Julian, Primo, Daniel, Ayala, Rosa M., Ferrer-Lores, Blanca, Ballesteros, Joan, Martinez-Lopez, Joaquin

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A novel ex vivo high-throughput assay reveals antiproliferative effects of idelalisib and ibrutinib in chronic lymphocytic leukemia von Primo, Daniel, Scarfò, Lydia, Xochelli, Aliki, Mattsson, Mattias, Ranghetti, Pamela, Espinosa, Ana Belén, Robles, Alicia, Gorrochategui, Julian, Martínez-López, Joaquín, de la Serna, Javier, González, Marcos, Gil, Alberto Chaparro, Anguita, Eduardo, Iraheta, Sandra, Munugalavadla, Veerendra, Quéva, Christophe, Tannheimer, Stacey, Rosenquist, Richard, Stamatopoulos, Kostas, Ballesteros, Joan, Ghia, Paolo

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Precision Medicine Test Is Similar but Faster Than Conventional Cytogenetics Predicting Response in AML Patients and Provides Alternative Treatments von Ballesteros, Joan, Martínez-Cuadron, David, Martinez Lopez, Joaquin, Bergua Burgues, Juan Miguel Miguel, Tormo, Mar, Serrano, Josefina, González, Ataulfo, Perez De Oteyza, Jaime, Vives, Susana, Vidriales, Maria-Belen, Herrera, Pilar, Vera, Juan Antonio, Martinez, Aurelio Lopez, de la Fuente, Adolfo, Barciela, Lourdes Amador, Hernandez-Rivas, Jose Angel, Fernandez Fernandez, Maria Angeles, Cervero, Carlos, Morillo, Daniel, Hernandez, Pilar, Primo, Daniel, Gorrochategui, Julian, Rojas, Jose Luis, Troconiz, Iñaki, Villoria, Jesús, Sanz, Miguel, Montesinos, Pau

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An Innovative High-Throughput Ex Vivo Drug Assay Incorporating the Native Microenvironment Reveals a Novel Mechanism of Action of Idelalisib in CLL von Ballesteros, Joan, Scarfo, Lydia, Mattsson, Mattias, Xochelli, Aliki, Ranghetti, Pamela, Primo, Daniel, Robles, Alicia, Gorrochategui, Julian, Martinez-Lopez, Joaquin, De la Serna, Javier, González, Marcos, Munugalavadla, Veerendra, Rosenquist, Richard, Stamatopoulos, Kostas, Quéva, Christophe, Ghia, Paolo

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Novel Assay for Ex Vivo Evaluation of Antiproliferative Effect of Hypomethylating Agents 5-Azacytidine and Decitabine in AML Patient Samples von Hernandez, Pilar, Montesinos, Pau, Serrano, Josefina, Herrera, Pilar, Bergua, Juan Pedro, Colorado, Mercedes, Gonzalez, Bernando J, Gomez, Cristina, Robles, Alicia, Gorrochategui, Julian, Sanchez, Jesus, Ballesteros, Joan, Moscardo, Federico, Martinez, David, Sanz, Miguel Angel, Pérez de Oteyza, Jaime, Martinez, Joaquin

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Development of a High-Throughput Screening Assay with Nurse-like Cell-Based Microenviroment in Chronic Lymphoid Leukemia Cells von Primo, Daniel, De la Serna, Javier, Martinez, Joaquin, González, Marcos, Lopez, Javier, Bárez, Abelardo, Ortiz, Macarena, Loscertales, Javier, Vidán, Julian, Rodriguez, Alicia, Polo, Marta, Irhaeta, Sandra, Alonso, Jose Maria, Queizan, Jose Antonio, Hernandez Rivas, Jose Angel, Peñarrubia, María Jesus, Gorrochategui, Julian, Espinosa, Ana Belen, Arroyo, Elena, Oates, Melanie, Pettit, Andrew R, Ballesteros, Joan, Hernandez, Pilar

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Biomarker‑driven phase Ib clinical trial of OPB‑111077 in acute myeloid leukemia von Martínez-López, Joaquín, Montesinos, Pau, López-Muñoz, Nieves, Ayala, Rosa, Martínez-Sánchez, Pilar, Gorrochategui, Julian, Rojas-Rudilla, José Luis, Primo, Daniel, Bergua-Burgues, Juan-Miguel, Calbacho, María, Acuña-Cruz, Evelyn, Pérez-Simón, José Antonio, De La Fuente, Adolfo, Pérez De Oteyza, Jaime, Rodriguez-Veiga, Rebeca, Pina, José Sánchez, Boluda, Blanca, Cano, Isabel, Paciello Coronel, María Liz, Ballesteros, Juan

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