Nuclear assembly as a target for anti-cancer therapies von Gorjánácz, Mátyás

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Lipin is required for efficient breakdown of the nuclear envelope in Caenorhabditis elegans von Gorjánácz, Mátyás, Mattaj, Iain W

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LEM-4 promotes rapid dephosphorylation of BAF during mitotic exit von Gorjánácz, Mátyás

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The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration von Bone, Courtney R, Tapley, Erin C, Gorjánácz, Mátyás, Starr, Daniel A

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What can Caenorhabditis elegans tell us about the nuclear envelope? von Gorjánácz, Mátyás, Jaedicke, Andreas, Mattaj, Iain W.

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The compartmentalized bacteria of the planctomycetes-verrucomicrobia-chlamydiae superphylum have membrane coat-like proteins von Santarella-Mellwig, Rachel, Franke, Josef, Jaedicke, Andreas, Gorjánácz, Mátyás, Bauer, Ulrike, Budd, Aidan, Mattaj, Iain W, Devos, Damien P

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Discovery and Characterization of BAY-184: A New Potent and Selective Acylsulfonamide-Benzofuran In Vivo-Active KAT6AB Inhibitor von ter Laak, Antonius, Hillig, Roman C., Ferrara, Steven J., Korr, Daniel, Barak, Naomi, Lienau, Philip, Herbert, Simon, Fernández-Montalván, Amaury Ernesto, Neuhaus, Roland, Gorjánácz, Mátyás, Puetter, Vera, Badock, Volker, Bone, Wilhelm, Strathdee, Craig, Siegel, Franziska, Schatz, Christoph, Nowak-Reppel, Katrin, Doehr, Olaf, Gradl, Stefan, Hartung, Ingo V., Meyerson, Matthew, Bouché, Léa

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Abstract LB-123: Pulsatile inhibition of PI3K converts immune suppression by Tregs and M2-TAM to anti-tumor immune response in animal models insensitive or resistant to the monothe... von Glaeske, Sarah, Huebner, Franziska, Anurin, Anna, Janzer, Andreas, Zitzmann-Kolbe, Sabine, Paul, Juliane, Glaeske, Katja, Berndt, Sandra, Mumberg, Dominik, Gorjanacz, Matyas, Ziegelbauer, Karl, Kreft, Bertolt, Liu, Ningshu

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Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor von Gutcher, Ilona, Kober, Christina, Roese, Lars, Roewe, Julian, Schmees, Norbert, Prinz, Florian, Gorjanacz, Matyas, Roehn, Ulrike, Bader, Benjamin, Irlbacher, Horst, Stoeckigt, Detlef, Carretero, Rafael, Sahm, Katharina, Oezen, Iris, Weinmann, Hilmar, Hartung, Ingo V., Kreft, Bertolt, Platten, Michael

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Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design von Rahm, Fredrik, Viklund, Jenny, Trésaugues, Lionel, Ellermann, Manuel, Giese, Anja, Ericsson, Ulrika, Forsblom, Rickard, Ginman, Tobias, Günther, Judith, Hallberg, Kenth, Lindström, Johan, Persson, Lars Boukharta, Silvander, Camilla, Talagas, Antoine, Díaz-Sáez, Laura, Fedorov, Oleg, Huber, Kilian V. M, Panagakou, Ioanna, Siejka, Paulina, Gorjánácz, Mátyás, Bauser, Marcus, Andersson, Martin

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Coordination of Kinase and Phosphatase Activities by Lem4 Enables Nuclear Envelope Reassembly during Mitosis von Asencio, Claudio, Davidson, Iain F., Santarella-Mellwig, Rachel, Ly-Hartig, Thi Bach Nga, Mall, Moritz, Wallenfang, Matthew R., Mattaj, Iain W., Gorjánácz, Mátyás

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Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target von Ellermann, Manuel, Eheim, Ashley, Rahm, Fredrik, Viklund, Jenny, Guenther, Judith, Andersson, Martin, Ericsson, Ulrika, Forsblom, Rickard, Ginman, Tobias, Lindström, Johan, Silvander, Camilla, Trésaugues, Lionel, Giese, Anja, Bunse, Stefanie, Neuhaus, Roland, Weiske, Jörg, Quanz, Maria, Glasauer, Andrea, Nowak-Reppel, Katrin, Bader, Benjamin, Irlbacher, Horst, Meyer, Hanna, Queisser, Nina, Bauser, Marcus, Haegebarth, Andrea, Gorjánácz, Mátyás

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Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action von Fernández-Montalván, Amaury E, Berger, Markus, Kuropka, Benno, Koo, Seong Joo, Badock, Volker, Weiske, Joerg, Puetter, Vera, Holton, Simon J, Stöckigt, Detlef, ter Laak, Antonius, Centrella, Paolo A, Clark, Matthew A, Dumelin, Christoph E, Sigel, Eric A, Soutter, Holly H, Troast, Dawn M, Zhang, Ying, Cuozzo, John W, Keefe, Anthony D, Roche, Didier, Rodeschini, Vincent, Chaikuad, Apirat, Díaz-Sáez, Laura, Bennett, James M, Fedorov, Oleg, Huber, Kilian V. M, Hübner, Jan, Weinmann, Hilmar, Hartung, Ingo V, Gorjánácz, Mátyás

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Samp1 is a component of TAN lines and is required for nuclear movement von Borrego-Pinto, Joana, Jegou, Thibaud, Osorio, Daniel S, Auradé, Frederic, Gorjánácz, Mátyás, Koch, Birgit, Mattaj, Iain W, Gomes, Edgar R

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Abstract 2866: BAY 3375968: An afucosylated anti-CCR8 antibody depleting activated intratumoral regulatory T cells as a cancer immunotherapy von Roider, Helge, Tseng, Su-Yi, Hoff, Sabine, Berndt, Sandra, Filarski, Katharina, Gritzan, Uwe, Stelte-Ludwig, Beatrix, Nadler, Wiebke M., Grudzinska-Goebel, Joanna, Ellinger, Philipp, Trautwein, Mark, Gorjanacz, Matyas

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ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication von Koo, Seong Joo, Fernández-Montalván, Amaury E, Badock, Volker, Ott, Christopher J, Holton, Simon J, von Ahsen, Oliver, Toedling, Joern, Vittori, Sarah, Bradner, James E, Gorjánácz, Mátyás

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Abstract 5226: Novel class of potent and selective inhibitors efface MTH1 as broad-spectrum cancer target von Ellermann, Manuel, Giese, Anja, Eheim, Ashley, Bunse, Stefanie, Neuhaus, Roland, Weiske, Jörg, Quanz, Maria, Glasauer, Andrea, Rahm, Fredrik, Viklund, Jenny, Andersson, Martin, Ginman, Tobias, Forsblom, Rickard, Lindström, Johan, Trésaugues, Lionel, Gorjanacz, Matyas

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Abstract 689: Identification and optimization of novel chemical matter via a structure-based approach resulting in a probe for MTH1 von Bauser, Marcus, Giese, Anja, Ellermann, Manuel, Guenther, Judith, Eheim, Ashley, Bunse, Stefanie, Neuhaus, Roland, Weiske, Joerg, Quanz, Maria, Glasauer, Andrea, Nowak-Reppel, Katrin, Bader, Benjamin, Irlbacher, Horst, Meyer, Hanna, Queisser, Nina, Haegebarth, Andrea, Gorjanacz, Matyas, Tresaugues, Lionel, Ginman, Tobias, Rahm, Fredrik, Andersson, Martin, Ericsson, Ulrica, Forsblom, Rickard, Lindstroem, Johan, Silvander, Camilla, Vicklund, Jenny

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Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses von Heller, Simon, Glaeske, Sarah, Gluske, Katja, Paul, Juliane, Böhme, Annika, Janzer, Andreas, Roider, Helge Gottfried, Montebaur, Anna, Nicke, Barbara, Lesche, Ralf, von Ahsen, Oliver, Politz, Oliver, Liu, Ningshu, Gorjánácz, Mátyás

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Coordination of Di-Acetylated Histone Ligands by the ATAD2 Bromodomain von Evans, Chiara M, Phillips, Margaret, Malone, Kiera L, Tonelli, Marco, Cornilescu, Gabriel, Cornilescu, Claudia, Holton, Simon J, Gorjánácz, Mátyás, Wang, Liping, Carlson, Samuel, Gay, Jamie C, Nix, Jay C, Demeler, Borries, Markley, John L, Glass, Karen C

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