Identification of (R)‑N‑((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)‑1H‑indole-3-carboxamide (CPI-1205),... von Vaswani, Rishi G, Gehling, Victor S, Dakin, Les A, Cook, Andrew S, Nasveschuk, Christopher G, Duplessis, Martin, Iyer, Priyadarshini, Balasubramanian, Srividya, Zhao, Feng, Good, Andrew C, Campbell, Robert, Lee, Christina, Cantone, Nico, Cummings, Richard T, Normant, Emmanuel, Bellon, Steven F, Albrecht, Brian K, Harmange, Jean-Christophe, Trojer, Patrick, Audia, James E, Zhang, Ying, Justin, Neil, Chen, Shuyang, Wilson, Jon R, Gamblin, Steven J

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Molecular Shape and Medicinal Chemistry: A Perspective von Nicholls, Anthony, McGaughey, Georgia B, Sheridan, Robert P, Good, Andrew C, Warren, Gregory, Mathieu, Magali, Muchmore, Steven W, Brown, Scott P, Grant, J. Andrew, Haigh, James A, Nevins, Neysa, Jain, Ajay N, Kelley, Brian

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Optimization of CAMD techniques 3. Virtual screening enrichment studies: a help or hindrance in tool selection? von Good, Andrew C., Oprea, Tudor I.

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Discovery, design, and synthesis of indole-based EZH2 inhibitors von Gehling, Victor S., Vaswani, Rishi G., Nasveschuk, Christopher G., Duplessis, Martin, Iyer, Priyadarshini, Balasubramanian, Srividya, Zhao, Feng, Good, Andrew C., Campbell, Robert, Lee, Christina, Dakin, Les A., Cook, Andrew S., Gagnon, Alexandre, Harmange, Jean-Christophe, Audia, James E., Cummings, Richard T., Normant, Emmanuel, Trojer, Patrick, Albrecht, Brian K.

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GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1 von Taylor, Alexander M., Bailey, Chris, Belmont, Lisa D., Campbell, Robert, Cantone, Nico, Côté, Alexandre, Crawford, Terry D., Cummings, Richard, DeMent, Kevin, Duplessis, Martin, Flynn, Megan, Good, Andrew C., Huang, Hon-Ren, Joshi, Shivangi, Leblanc, Yves, Murray, Jeremy, Nasveschuk, Christopher G., Neiss, Adrianne, Poy, Florence, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Tsui, Vickie, Zawadzke, Laura, Sims, Robert J., Audia, James E., Bellon, Steven F., Magnuson, Steven R., Albrecht, Brian K., Cochran, Andrea G.

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Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Inf... von Scola, Paul M., Wang, Alan Xiangdong, Good, Andrew C., Sun, Li-Qiang, Combrink, Keith D., Campbell, Jeffrey A., Chen, Jie, Tu, Yong, Sin, Ny, Venables, Brian L., Sit, Sing-Yuen, Chen, Yan, Cocuzza, Anthony, Bilder, Donna M., D’Andrea, Stanley, Zheng, Barbara, Hewawasam, Piyasena, Ding, Min, Thuring, Jan, Li, Jianqing, Hernandez, Dennis, Yu, Fei, Falk, Paul, Zhai, Guangzhi, Sheaffer, Amy K., Chen, Chaoqun, Lee, Min S., Barry, Diana, Knipe, Jay O., Li, Wenying, Han, Yong-Hae, Jenkins, Susan, Gesenberg, Christoph, Gao, Qi, Sinz, Michael W., Santone, Kenneth S., Zvyaga, Tatyana, Rajamani, Ramkumar, Klei, Herbert E., Colonno, Richard J., Grasela, Dennis M., Hughes, Eric, Chien, Caly, Adams, Stephen, Levesque, Paul C., Li, Danshi, Zhu, Jialong, Meanwell, Nicholas A., McPhee, Fiona

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Implications of Promiscuous Pim-1 Kinase Fragment Inhibitor Hydrophobic Interactions for Fragment-Based Drug Design von Good, Andrew C, Liu, Jinyu, Hirth, Bradford, Asmussen, Gary, Xiang, Yibin, Biemann, Hans-Peter, Bishop, Kimberly A, Fremgen, Trisha, Fitzgerald, Maria, Gladysheva, Tatiana, Jain, Annuradha, Jancsics, Katherine, Metz, Markus, Papoulis, Andrew, Skerlj, Renato, Stepp, J. David, Wei, Ronnie R

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Electrophilic Helical Peptides That Bond Covalently, Irreversibly, and Selectively in a Protein–Protein Interaction Site von de Araujo, Aline Dantas, Lim, Junxian, Good, Andrew C, Skerlj, Renato T, Fairlie, David P

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Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor von Zheng, Barbara, D’Andrea, Stanley V, Sun, Li-Qiang, Wang, Alan Xiangdong, Chen, Yan, Hrnciar, Peter, Friborg, Jacques, Falk, Paul, Hernandez, Dennis, Yu, Fei, Sheaffer, Amy K, Knipe, Jay O, Mosure, Kathy, Rajamani, Ramkumar, Good, Andrew C, Kish, Kevin, Tredup, Jeffrey, Klei, Herbert E, Paruchuri, Manjula, Ng, Alicia, Gao, Qi, Rampulla, Richard A, Mathur, Arvind, Meanwell, Nicholas A, McPhee, Fiona, Scola, Paul M

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P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor von Venables, Brian L., Sin, Ny, Wang, Alan Xiangdong, Sun, Li-Qiang, Tu, Yong, Hernandez, Dennis, Sheaffer, Amy, Lee, Min, Dunaj, Cindy, Zhai, Guangzhi, Barry, Diana, Friborg, Jacques, Yu, Fei, Knipe, Jay, Sandquist, Jason, Falk, Paul, Parker, Dawn, Good, Andrew C., Rajamani, Ramkumar, McPhee, Fiona, Meanwell, Nicholas A., Scola, Paul M.

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Hepatitis C Virus NS5A Replication Complex Inhibitors. Part 6: Discovery of a Novel and Highly Potent Biarylimidazole Chemotype with Inhibitory Activity Toward Genotypes 1a and 1b... von Belema, Makonen, Nguyen, Van N., Romine, Jeffrey L., St. Laurent, Denis R., Lopez, Omar D., Goodrich, Jason T., Nower, Peter T., O’Boyle, Donald R., Lemm, Julie A., Fridell, Robert A., Gao, Min, Fang, Hua, Krause, Rudolph G., Wang, Ying-Kai, Oliver, A. Jayne, Good, Andrew C., Knipe, Jay O., Meanwell, Nicholas A., Snyder, Lawrence B.

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Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE) von Boy, Kenneth M., Guernon, Jason M., Wu, Yong-Jin, Zhang, Yunhui, Shi, Joe, Zhai, Weixu, Zhu, Shirong, Gerritz, Samuel W., Toyn, Jeremy H., Meredith, Jere E., Barten, Donna M., Burton, Catherine R., Albright, Charles F., Good, Andrew C., Grace, James E., Lentz, Kimberley A., Olson, Richard E., Macor, John E., Thompson, Lorin A.

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An Empirical Process for the Design of High-Throughput Screening Deck Filters von Pearce, Bradley C, Sofia, Michael J, Good, Andrew C, Drexler, Dieter M, Stock, David A

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HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologies von Lopez, Omar D, Nguyen, Van N, St. Laurent, Denis R, Belema, Makonen, Serrano-Wu, Michael H, Goodrich, Jason T, Yang, Fukang, Qiu, Yuping, Ripka, Amy S, Nower, Peter T, Valera, Lourdes, Liu, Mengping, O’Boyle, Donald R., II, Sun, Jin-Hua, Fridell, Robert A, Lemm, Julie A, Gao, Min, Good, Andrew C, Meanwell, Nicholas A, Snyder, Lawrence B

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Incidence and characterization of diagnosed endometriosis in a geographically defined population von Leibson, Cynthia L, Good, Andrew E, Hass, Steven L, Ransom, Jeanine, Yawn, Barbara P, O'Fallon, W.Michael, Melton, L.Joseph

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HCV NS5A replication complex inhibitors. Part 5: Discovery of potent and pan-genotypic glycinamide cap derivatives von Belema, Makonen, Nguyen, Van N., St. Laurent, Denis R., Lopez, Omar D., Qiu, Yuping, Good, Andrew C., Nower, Peter T., Valera, Lourdes, O’Boyle, Donald R., Sun, Jin-Hua, Liu, Mengping, Fridell, Robert A., Lemm, Julie A., Gao, Min, Knipe, Jay O., Meanwell, Nicholas A., Snyder, Lawrence B.

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Monosubstituted γ-lactam and conformationally constrained 1,3-diaminopropan-2-ol transition-state isostere inhibitors of β-secretase (BACE) von Boy, Kenneth M., Guernon, Jason M., Shi, Jianliang, Toyn, Jeremy H., Meredith, Jere E., Barten, Donna M., Burton, Catherine R., Albright, Charles F., Marcinkeviciene, Jovita, Good, Andrew C., Tebben, Andrew J., Muckelbauer, Jodi K., Camac, Daniel M., Lentz, Kimberley A., Bronson, Joanne J., Olson, Richard E., Macor, John E., Thompson, Lorin A.

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Wake field study of tidal turbines under realistic flow conditions von Thiébot, Jérôme, Guillou, Nicolas, Guillou, Sylvain, Good, Andrew, Lewis, Michael

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CFT7455, a Novel IKZF1/3 Degrader, Demonstrates Potent Anti-Tumor Activity in Models of Non-Hodgkin's Lymphoma As a Single Agent or in Combination with Clinically Approved Agents von Perino, Samantha, Kirby, R. Jason, Agafonov, Roman, Chaturvedi, Prasoon, Eron, Scott, Good, Andrew, Hart, Ashley, He, Minsheng, Lobbardi, Riadh, Phillips, Andrew J, Proia, David, Henderson, James, Thomeius, Michael, Nasveschuk, Christopher, Fisher, Stewart L, Pollock, Roy Macfarlane

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Measuring CAMD technique performance: A virtual screening case study in the design of validation experiments von Good, Andrew C., Hermsmeier, Mark A., Hindle, S.A.

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