Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors von Gonzalez-Lopez de Turiso, Felix, Sun, Daqing, Rew, Yosup, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Correll, Tiffany L, Huang, Xin, Julian, Lisa D, Kayser, Frank, Lo, Mei-Chu, Long, Alexander M, McMinn, Dustin, Oliner, Jonathan D, Osgood, Tao, Powers, Jay P, Saiki, Anne Y, Schneider, Steve, Shaffer, Paul, Xiao, Shou-Hua, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H

Volltext

Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation In Vivo von Jones, J. Howard, Xin, Zhili, Himmelbauer, Martin, Dechantsreiter, Michael, Enyedy, Istvan, Hedde, Joseph, Fang, Terry, Coomaraswamy, Janaky, King, Kristopher W, Murugan, Paramasivam, Santoro, Joseph C, Hesson, Thomas, Walther, Dirk M, Wei, Ru, Zheng, Fengmei, Marcotte, Douglas J, Spilker, Kerri, Kumar, P. Rajesh, Liu, Ying, Gilfillan, Rab, Gonzalez-Lopez de Turiso, Felix

Volltext

Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis von Himmelbauer, Martin K., Bajrami, Bekim, Basile, Rebecca, Capacci, Andrew, Chen, TeYu, Choi, Colin K., Gilfillan, Rab, Gonzalez-Lopez de Turiso, Felix, Gu, Chungang, Hoemberger, Marc, Johnson, Douglas S., Jones, J. Howard, Kadakia, Ekta, Kirkland, Melissa, Lin, Edward Y., Liu, Ying, Ma, Bin, Magee, Tom, Mantena, Srinivasa, Marx, Isaac E., Metrick, Claire M., Mingueneau, Michael, Murugan, Paramasivam, Muste, Cathy A., Nadella, Prasad, Nevalainen, Marta, Parker Harp, Chelsea R., Pattaropong, Vatee, Pietrasiewicz, Alicia, Prince, Robin J., Purgett, Thomas J., Santoro, Joseph C., Schulz, Jurgen, Sciabola, Simone, Tang, Hao, Vandeveer, H. George, Wang, Ti, Yousaf, Zain, Helal, Christopher J., Hopkins, Brian T.

Volltext

Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo von Halkina, Tamara, Henderson, Jaclyn L, Lin, Edward Y, Himmelbauer, Martin K, Jones, J. Howard, Nevalainen, Marta, Feng, Jun, King, Kristopher, Rooney, Michael, Johnson, Joshua L, Marcotte, Douglas J, Chodaparambil, Jayanth V, Kumar, P. Rajesh, Patterson, Thomas A, Murugan, Paramasivam, Schuman, Eli, Wong, LaiYee, Hesson, Thomas, Lamore, Sarah, Bao, Channa, Calhoun, Michael, Certo, Hannah, Amaral, Brenda, Dillon, Gregory M, Gilfillan, Rab, de Turiso, Felix Gonzalez-Lopez

Volltext

Synthetic studies towards furanocembrane diterpenes. A total synthesis of bis-deoxylophotoxin von Cases, Manuel, Gonzalez-Lopez de Turiso, Felix, Hadjisoteriou, Maria S, Pattenden, Gerald

Volltext

Synthesis of spirocyclopentene-indolines by intramolecular alkylidine insertion reactions von Whipp, Christopher J., de Turiso, Felix Gonzalez-Lopez

Volltext

Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors von Xin, Zhili, Himmelbauer, Martin K, Jones, J. Howard, Enyedy, Istvan, Gilfillan, Rab, Hesson, Thomas, King, Kristopher, Marcotte, Douglas J, Murugan, Paramasivam, Santoro, Joseph C, Gonzalez-Lopez de Turiso, Felix

Volltext

An Efficient and Scalable One-Pot Double Michael Addition-Dieckmann Condensation for the Synthesis of 4,4-Disubstituted Cyclohexane β-Keto Esters von DeGraffenreid, Michael R, Bennett, Sarah, Caille, Sebastien, Gonzalez-Lopez de Turiso, Felix, Hungate, Randall W, Julian, Lisa D, Kaizerman, Jacob A, McMinn, Dustin L, Rew, Yosup, Sun, Daqing, Yan, Xuelei, Powers, Jay P

Volltext

Discovery of AMG 853, a CRTH2 and DP Dual Antagonist von Liu, Jiwen, Li, An-Rong, Wang, Yingcai, Johnson, Mike G, Su, Yongli, Shen, Wang, Wang, Xuemei, Lively, Sarah, Brown, Matthew, Lai, SuJen, Gonzalez Lopez De Turiso, Felix, Xu, Qingge, Van Lengerich, Bettina, Schmitt, Mike, Fu, Zice, Sun, Ying, Lawlis, Shanna, Seitz, Lisa, Danao, Jay, Wait, Jill, Ye, Qiuping, Tang, Hua Lucy, Grillo, Mark, Collins, Tassie L, Sullivan, Timothy J, Medina, Julio C

Volltext

Radical Cyclization Approach to Spirocyclohexadienones von González-López de Turiso, Felix, Curran, Dennis P

Volltext

Concise synthesis of stereodefined, thiazole—containing cyclic hexa- and octapeptide relatives of the Lissoclinums, via cyclooligomerisation reactions von Bertram, Anna, Blake, Alexander J, Turiso, Felix González-López de, Hannam, Jeffery S, Jolliffe, Katrina A, Pattenden, Gerald, Skae, Michael

Volltext

Pyridine macrocycle compounds as ASK1 inhibiting agents von Gonzalez Lopez de Turiso, Felix

Volltext bestellen

Compuestos macrocíclicos de piridina como agentes inhibidores de ASK1 von GONZALEZ LOPEZ DE TURISO, Felix

Volltext bestellen

PYRIDINE MACROCYCLE COMPOUNDS AS ASK1 INHIBITING AGENTS von Gonzalez Lopez de Turiso, Felix

Volltext bestellen

Derivados de piperidinona como inhibidores de MDM2 para el tratamiento de cáncer von Gustin, Darin James, Yan, Xuelei, McGee, Lawrence R, McMinn, Dustin, Gribble, Jr, Zhu, Jiang, Chen, Xiaoqi, Heath, Julie Anne, Li, Zhihong, Mihalic, Jeffrey Thomas, Beck, Hilary Place, Jiao, Xianjun, Fu, Zice, Deignan, Jeffrey, Ma, Zhihua, Wang, Xiaodong, Huang, Xin, Lai, Sujen, Eksterowicz, John, Roveto, Philip Marley, Yu, Ming, Kayser, Frank, Kopecky, David John, Gonzalez Lopez de Turiso, Felix, McIntosh, Joel, Connors, Richard Victor, Olson, Steven Howard, Gonzalez Buenrostro, Ana, Fu, Jiasheng, Liu, Jiwen, Low, Jonathan Dante, Li, Yihong, Duquette, Jason A, Fox, Brian Matthew, Bartberger, Michael David, Sun, Daqing, Wang, Yingcai, Medina, Julio Cesar, Fisher, Benjamin, Johnson, Michael, Lucas, Brian Stuart, Rew, Yosup

Volltext bestellen

ChemInform Abstract: Synthesis of Spirocyclopentene-Indolines by Intramolecular Alkylidine Insertion Reactions von Whipp, Christopher J., Gonzalez-Lopez de Turiso, Felix

Volltext

Agentes inhibidores de ASK1 von HIMMELBAUER, Martin, GONZALEZ LOPEZ DE TURISO, Felix, JONES, John, XIN, Zhili

Volltext bestellen

ASK1 inhibiting agents von Gonzalez Lopez de Turiso, Felix, Himmelbauer, Martin, Xin, Zhili, Jones, John H

Volltext bestellen

ASK1 INHIBITING AGENTS von Gonzalez Lopez de Turiso, Felix, Himmelbauer, Martin, Dechantsreiter, Michael, Xin, Zhili, Jones, John H

Volltext bestellen

INHIBIDORES DE PROTEÍNA DE UNIÓN A EMOPAMIL Y USOS DE ESTOS von HIMMELBAUER, MARTIN, JONES, JOHN H, PRINCE, ROBIN, PATTAROPONG, VATEE, GONZALEZ LOPEZ DE TURISO, FELIX, LIN, EDWARD YIN SHIANG, XIN, ZHILI

Volltext bestellen