Highly Attenuated Poxvirus-Based Vaccines Against Emerging Viral Diseases von Perdiguero, Beatriz, Pérez, Patricia, Marcos-Villar, Laura, Albericio, Guillermo, Astorgano, David, Álvarez, Enrique, Sin, Laura, Gómez, Carmen Elena, García-Arriaza, Juan, Esteban, Mariano

Volltext

NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses von Di Pilato, Mauro, Mejías-Pérez, Ernesto, Zonca, Manuela, Perdiguero, Beatriz, Gómez, Carmen Elena, Trakala, Marianna, Nieto, Jacobo, Nájera, José Luis, Sorzano, Carlos Oscar S., Combadière, Christophe, Pantaleo, Giuseppe, Planelles, Lourdes, Esteban, Mariano

Volltext

Insertion of vaccinia virus C7L host range gene into NYVAC-B genome potentiates immune responses against HIV-1 antigens von Nájera, José Luis, Gómez, Carmen Elena, García-Arriaza, Juan, Sorzano, Carlos Oscar, Esteban, Mariano

Volltext

Immunogenicity and efficacy of a novel multi-patch SARS-CoV-2/COVID-19 vaccine candidate von Perdiguero, Beatriz, Marcos-Villar, Laura, López-Bravo, María, Sánchez-Cordón, Pedro J, Zamora, Carmen, Valverde, José Ramón, Sorzano, Carlos Óscar S, Sin, Laura, Álvarez, Enrique, Ramos, Manuel, Del Val, Margarita, Esteban, Mariano, Gómez, Carmen Elena

Volltext

An MVA-based vector expressing cell-free ISG15 increases IFN-I production and improves HIV-1-specific CD8 T cell immune responses von Falqui, Michela, Perdiguero, Beatriz, Coloma, Rocio, Albert, Manuel, Marcos-Villar, Laura, McGrail, Joseph Patrick, Sorzano, Carlos Óscar S, Esteban, Mariano, Gómez, Carmen Elena, Guerra, Susana

Volltext

Removal of Vaccinia Virus Genes That Block Interferon Type I and II Pathways Improves Adaptive and Memory Responses of the HIV/AIDS Vaccine Candidate NYVAC-C in Mice von GOMEZ, Carmen Elena, PERDIGUERO, Beatriz, NAJERA, Jose Luis, SORZANO, Carlos Oscar S, JIMENEZ, Victoria, GONZALEZ-SANZ, Rubén, ESTEBAN, Mariano

Volltext

The HIV/AIDS Vaccine Candidate MVA-B Administered as a Single Immunogen in Humans Triggers Robust, Polyfunctional, and Selective Effector Memory T Cell Responses to HIV-1 Antigens von GOMEZ, Carmen Elena, NAJERA, José Luis, GUARDO, Alberto C, GARCIA, Felipe, GATELL, Jose M, PLANA, Montserrat, ESTEBAN, Mariano, PERDIGUERO, Beatriz, GARCIA-ARRIAZA, Juan, SORZANO, Carlos Oscar S, JIMENEZ, Victoria, GONZALEZ-SANZ, Rubén, JIMENEZ, José Luis, MUNOZ-FERNANDEZ, Maria Angeles, LOPEZ BERNALDO DE QUIROS, Juan Carlos

Volltext

Emerging SARS-CoV-2 Variants and Impact in Global Vaccination Programs against SARS-CoV-2/COVID-19 von Gomez, Carmen Elena, Perdiguero, Beatriz, Esteban, Mariano

Volltext

Potency and durability of T and B cell immune responses after homologous and heterologous vector delivery of a trimer-stabilized, membrane-displayed HIV-1 clade ConC Env protein von Perdiguero, Beatriz, Hauser, Alexandra, Gómez, Carmen Elena, Peterhoff, David, Sideris, Elefthéria, Sorzano, Carlos Óscar S, Wilmschen, Sarah, Schaber, Marion, Stengel, Laura, Asbach, Benedikt, Ding, Song, Von Laer, Dorothee, Levy, Yves, Pantaleo, Giuseppe, Kimpel, Janine, Esteban, Mariano, Wagner, Ralf

Volltext

Unveiling the Multifaceted Roles of ISG15: From Immunomodulation to Therapeutic Frontiers von Álvarez, Enrique, Falqui, Michela, Sin, Laura, McGrail, Joseph Patrick, Perdiguero, Beatriz, Coloma, Rocío, Marcos-Villar, Laura, Tárrega, Céline, Esteban, Mariano, Gómez, Carmen Elena, Guerra, Susana

Volltext

New vaccinia virus promoter as a potential candidate for future vaccines von Di Pilato, Mauro, Mejías-Pérez, Ernesto, Gómez, Carmen Elena, Perdiguero, Beatriz, Sorzano, Carlos Oscar S, Esteban, Mariano

Volltext

The Combination of an mRNA Immunogen, a TLR7 Agonist and a PD1 Blocking Agent Enhances In-Vitro HIV T-Cell Immune Responses von Usero, Lorena, Leal, Lorna, Gómez, Carmen Elena, Miralles, Laia, Aurrecoechea, Elena, Esteban, Ignasi, Torres, Berta, Inciarte, Alexy, Perdiguero, Beatriz, Esteban, Mariano, García, Felipe, Plana, Montserrat

Volltext

Assessment of Human SARS CoV-2-Specific T-Cell Responses Elicited In Vitro by New Computationally Designed mRNA Immunogens (COVARNA) von Esteban, Ignasi, Pastor-Quiñones, Carmen, Usero, Lorena, Aurrecoechea, Elena, Franceschini, Lorenzo, Esprit, Arthur, Gelpí, Josep Lluís, Martínez-Jiménez, Francisco, López-Bigas, Núria, Breckpot, Karine, Thielemans, Kris, Leal, Lorna, Gómez, Carmen Elena, Sisteré-Oró, Marta, Meyerhans, Andreas, Esteban, Mariano, Alonso, María José, García, Felipe, Plana, Montserrat

Volltext

Virological and immunological characterization of novel NYVAC-based HIV/AIDS vaccine candidates expressing clade C trimeric soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as virus... von Perdiguero, Beatriz, Gómez, Carmen Elena, Cepeda, Victoria, Sánchez-Sampedro, Lucas, García-Arriaza, Juan, Mejías-Pérez, Ernesto, Jiménez, Victoria, Sánchez, Cristina, Sorzano, Carlos Óscar S, Oliveros, Juan Carlos, Delaloye, Julie, Roger, Thierry, Calandra, Thierry, Asbach, Benedikt, Wagner, Ralf, Kibler, Karen V, Jacobs, Bertram L, Pantaleo, Giuseppe, Esteban, Mariano

Volltext

Attenuated and Replication-Competent Vaccinia Virus Strains M65 and M101 with Distinct Biology and Immunogenicity as Potential Vaccine Candidates against Pathogens von Lucas Sánchez-Sampedro, Carmen Elena Gómez, Ernesto Mejías-Pérez, Eva Pérez-Jiménez, Juan Carlos Oliveros, Mariano Esteban

Volltext

Cellular and Biochemical Differences between Two Attenuated Poxvirus Vaccine Candidates (MVA and NYVAC) and Role of the C7L Gene von NAJERA, José Luis, GOMEZ, Carmen Elena, DOMINGO-GIL, Elena, MAGDALENA GHERARDI, Maria, ESTEBAN, Mariano

Volltext

Modulating the immune response to SARS-CoV-2 by different nanocarriers delivering an mRNA expressing trimeric RBD of the spike protein: COVARNA Consortium von Marcos-Villar, Laura, Perdiguero, Beatriz, Anthiya, Shubaash, Borrajo, Mireya L., Lou, Gustavo, Franceschini, Lorenzo, Esteban, Ignasi, Sánchez-Cordón, Pedro J., Zamora, Carmen, Sorzano, Carlos Óscar S., Jordá, Luis, Codó, Laia, Gelpí, Josep L., Sisteré-Oró, Marta, Meyerhans, Andreas, Thielemans, Kris, Martínez-Jiménez, Francisco, López-Bigas, Núria, García, Felipe, Alonso, María J., Plana, Montserrat, Esteban, Mariano, Gómez, Carmen Elena

Volltext

Head-to-head comparison on the immunogenicity of two HIV/AIDS vaccine candidates based on the attenuated poxvirus strains MVA and NYVAC co-expressing in a single locus the HIV-1BX0... von Gómez, Carmen Elena, Nájera, Jose Luis, Jiménez, Eva Pérez, Jiménez, Victoria, Wagner, Ralf, Graf, Marcus, Frachette, Marie-Joelle, Liljeström, Peter, Pantaleo, Giuseppe, Esteban, Mariano

Volltext

Generation and immunogenicity of novel HIV/AIDS vaccine candidates targeting HIV-1 Env/Gag-Pol-Nef antigens of clade C von Gómez, Carmen Elena, Nájera, Jose Luis, Jiménez, Victoria, Bieler, Kurt, Wild, Jens, Kostic, Linda, Heidari, Shirin, Chen, Margaret, Frachette, Marie-Joelle, Pantaleo, Giuseppe, Wolf, Hans, Liljeström, Peter, Wagner, Ralf, Esteban, Mariano

Volltext

Enhancement of HIV-1 Env-Specific CD8 T Cell Responses Using Interferon-Stimulated Gene 15 as an Immune Adjuvant von Gomez, Carmen Elena, Perdiguero, Beatriz, Falqui, Michela, Marin, Maria Q., Becares, Martina, Sorzano, Carlos Oscar S., Garcia-Arriaza, Juan, Esteban, Mariano, Guerra, Susana

Volltext