Prediction of Benefit from Checkpoint Inhibitors in Mismatch Repair Deficient Metastatic Colorectal Cancer: Role of Tumor Infiltrating Lymphocytes von Loupakis, Fotios, Depetris, Ilaria, Biason, Paola, Intini, Rossana, Prete, Alessandra Anna, Leone, Francesco, Lombardi, Pasquale, Filippi, Roberto, Spallanzani, Andrea, Cascinu, Stefano, Bonetti, Luca Reggiani, Maddalena, Giulia, Valeri, Nicola, Sottoriva, Andrea, Zapata, Luis, Salmaso, Roberta, Munari, Giada, Rugge, Massimo, Dei Tos, Angelo Paolo, Golovato, Justin, Sanborn, John Z., Nguyen, Andrew, Schirripa, Marta, Zagonel, Vittorina, Lonardi, Sara, Fassan, Matteo

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Modified adenovirus induces antigen specific T cells and effector memory T cells in mice von Sieling, Peter A, Golovato, Justin, Niazi, Kayvan, Rabizadeh, Shahrooz

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Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution von Cheng, Jeffrey B., Sedgewick, Andrew J., Finnegan, Alex I., Harirchian, Paymann, Lee, Jerry, Kwon, Sunjong, Fassett, Marlys S., Golovato, Justin, Gray, Matthew, Ghadially, Ruby, Liao, Wilson, Perez White, Bethany E., Mauro, Theodora M., Mully, Thaddeus, Kim, Esther A., Sbitany, Hani, Neuhaus, Isaac M., Grekin, Roy C., Yu, Siegrid S., Gray, Joe W., Purdom, Elizabeth, Paus, Ralf, Vaske, Charles J., Benz, Stephen C., Song, Jun S., Cho, Raymond J.

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Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma von North, Jeffrey P., Golovato, Justin, Vaske, Charles J., Sanborn, J. Zachary, Nguyen, Andrew, Wu, Wei, Goode, Benjamin, Stevers, Meredith, McMullen, Kevin, Perez White, Bethany E., Collisson, Eric A., Bloomer, Michele, Solomon, David A., Benz, Stephen C., Cho, Raymond J.

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Reconstructing tumor history in breast cancer: signatures of mutational processes and response to neoadjuvant chemotherapy von Denkert, C., Untch, M., Benz, S., Schneeweiss, A., Weber, K.E., Schmatloch, S., Jackisch, C., Sinn, H.P., Golovato, J., Karn, T., Marmé, F., Link, T., Budczies, J., Nekljudova, V., Schmitt, W.D., Stickeler, E., Müller, V., Jank, P., Parulkar, R., Heinmöller, E., Sanborn, J.Z., Schem, C., Sinn, B.V., Soon-Shiong, P., van Mackelenbergh, M., Fasching, P.A., Rabizadeh, S., Loibl, S.

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1374 Virus-like DNA, a single-agent poly-functional therapeutic platform that potently activates anti-cancer protective immunity von Niazi, Kayvan R, Sieling, Peter A, Benz, Steve, Golovato, Justin, Rabizadeh, Shahrooz

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1373 SynBAd, a clinical cancer vaccine candidate, induces antigen-specific T cells and extends life in a therapeutic liver cancer model von Niazi, Kayvan R, Sieling, Peter A, Rabizadeh, Shahrooz, Benz, Steve, Golovato, Justin, Nolasco, Aleece

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Large scale, robust, and accurate whole transcriptome profiling from clinical formalin-fixed paraffin-embedded samples von Newton, Yulia, Sedgewick, Andrew J., Cisneros, Luis, Golovato, Justin, Johnson, Mark, Szeto, Christopher W., Rabizadeh, Shahrooz, Sanborn, J. Zachary, Benz, Stephen Charles, Vaske, Charles

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Abstract 3398: Analysis of whole transcriptome RNA-seq of large numbers of clinical FFPE samples von Newton, Yulia, Golovato, Justin, Johnson, Mark, Rabizadeh, Shahrooz, Sanborn, Zack, Benz, Steve, Vaske, Charles J.

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Human Tumor-Infiltrating MAIT Cells Display Hallmarks of Bacterial Antigen Recognition in Colorectal Cancer von Li, Shamin, Simoni, Yannick, Becht, Etienne, Loh, Chiew Yee, Li, Naisi, Lachance, Daniel, Koo, Si-Lin, Lim, Teck Por, Tan, Emile Kwong Wei, Mathew, Ronnie, Nguyen, Andrew, Golovato, Justin, Berkson, Julia D., Prlic, Martin, Lee, Bernett, Minot, Samuel S., Nagarajan, Niranjan, Dey, Neelendu, Tan, Daniel S.W., Tan, Iain B., Newell, Evan W.

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Loss of ZNF750 in ocular and cutaneous sebaceous carcinomas von North, Jeffrey P., Solomon, David A., Golovato, Justin, Bloomer, Michelle, Benz, Stephen C., Cho, Raymond J.

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114 The genomic landscape of sebaceous cell carcinoma von Cho, R.J., McMullen, K., Solomon, D., Benz, S., Golovato, J., Goode, B., North, J.P.

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Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates von Patananan, Alexander N., Sercel, Alexander J., Wu, Ting-Hsiang, Ahsan, Fasih M., Torres, Alejandro, Kennedy, Stephanie A.L., Vandiver, Amy, Collier, Amanda J., Mehrabi, Artin, Van Lew, Jon, Zakin, Lise, Rodriguez, Noe, Sixto, Marcos, Tadros, Wael, Lazar, Adam, Sieling, Peter A., Nguyen, Thang L., Dawson, Emma R., Braas, Daniel, Golovato, Justin, Cisneros, Luis, Vaske, Charles, Plath, Kathrin, Rabizadeh, Shahrooz, Niazi, Kayvan R., Chiou, Pei-Yu, Teitell, Michael A.

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A20 and ABIN1 Suppression of a Keratinocyte Inflammatory Program with a Shared Single-Cell Expression Signature in Diverse Human Rashes von Harirchian, Paymann, Lee, Jerry, Hilz, Stephanie, Sedgewick, Andrew J., Perez White, Bethany E., Kesling, Michael J., Mully, Thaddeus, Golovato, Justin, Gray, Matthew, Mauro, Theodora M., Purdom, Elizabeth, Kim, Esther A., Sbitany, Hani, Bhutani, Tina, Vaske, Charles J., Benz, Stephen C., Cho, Raymond J., Cheng, Jeffrey B.

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Loss of ZNF750 in ocular and cutaneous sebaceous carcinoma von North, Jeffrey P., Solomon, David A., Golovato, Justin, Bloomer, Michele, Benz, Stephen C., Cho, Raymond J.

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Abstract 2172: Proteogenomics of laser microdissected difficult-to-treat breast cancers identifies Basal and Her2 patients associated with outcome differences von Raj-Kumar, Praveen-Kumar, Liu, Tao, Sturtz, Lori A., Kovatich, Albert J., Gritsenko, Marina A., Petyuk, Vladislav A., Deyarmin, Brenda, Liu, Jianfang, Praveen-Kumar, Anupama, McDermott, Jason E., Shukla, Anil K., Moore, Ronald J., Monroe, Matthew E., Webb-Robertson, Bobbie-Jo M., Hooke, Jeffrey A., Fantacone-Campbell, Leigh, Kvecher, Leonid, Kane, Jennifer, Melley, Jennifer, Somiari, Stella, Benz, Stephen C., Golovato, Justin, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Smith, Richard D., Mural, Richard J., Rodland, Karin D., Shriver, Craig D., Li, Zhaoyu, Hu, Hai

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Longitudinal Transcriptome Analysis of Myelodysplatic Syndrome Progression to Acute Myeloid Leukemia: Implications for Prognosis von De Clara, Etienne, Ali, Abdullah Mahmood, Kayani, Jehanzeb, Szeto, Christopher, Golovato, Justin, Sedgewick, Andrew, Jurcic, Joseph G., Benz, Steve, Rabizadeh, Shahrooz, Raza, Azra

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Abstract P6-06-09: Evaluation of laser microdissected primary breast tumors for RNA Seq over bulk processing and validated with cohort control von Raj-Kumar, Praveen-Kumar, Sturtz, Lori A., Kovatich, Albert J., Deyarmin, Brenda, Hooke, Jeffrey A., Fantacone-Campbell, Leigh, Praveen-Kumar, Anupama, Liu, Jianfang, Craig, James, Kvecher, Leonid, Kane, Jennifer, Melley, Jennifer, Somiari, Stella, Benz, Stephen C., Golovato, Justin, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Mural, Richard, Shriver, Craig D., Hu, Hai

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Abstract 3402: Evaluation of laser microdissected primary breast tumors for RNA-Seq over bulk processing von Raj-Kumar, Praveen-Kumar, Sturtz, Lori A., Kovatich, Albert J., Deyarmin, Brenda, Hooke, Jeffrey A., Fantacone-Campbell, Leigh, Praveen-Kumar, Anupama, Liu, Jianfang, Craig, James, Kvecher, Leonid, Kane, Jennifer, Melley, Jennifer, Somiari, Stella, Benz, Stephen C., Golovato, Justin, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Mural, Richard J., Shriver, Craig D., Hu, Hai

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Genomic and immune infiltration differences between MSI and MSS GI tumors von Newton, Yulia, Golovato, Justin, Tan, Iain Beehuat, Lam, Justina Yick Ching, Yu, Guo, Koo, Si-Lin, Chua, Clarinda, Yeong, Joe Poh Sheng, Ping, Christine, Skanderup, Anders, Göke, Jonathan, Johnson, Mark, Rabizadeh, Shahrooz, Sanborn, J Zachary, Benz, Stephen Charles, Vaske, Charles Joseph, Szeto, Christopher

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