X-Ray Crystal Structures of Human Immunodeficiency Virus Type 1 Protease Mutants Complexed with Atazanavir von KLEI, Herbert E, KISH, Kevin, SHERIFF, Steven, LIN, Pin-Fang M, QI GUO, FRIBORG, Jacques, ROSE, Ronald E, YAQUN ZHANG, GOLDFARB, Valentina, LANGLEY, David R, WITTEKIND, Michael

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Backbone and Side Chain Dynamics of Uncomplexed Human Adipocyte and Muscle Fatty Acid-Binding Proteins von Constantine, Keith L, Friedrichs, Mark S, Wittekind, Michael, Jamil, Haris, Chu, Ching-Hsuen, Parker, Rex A, Goldfarb, Valentina, Mueller, Luciano, Farmer, Bennett T

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Localizing the NADP + binding site on the MurB enzyme by NMR von Farmer, Bennett T, Constantine, Keith L, Goldfarb, Valentina, Friedrichs, Mark S, Wittekind, Michael, Yanchunas, Joseph, Robertson, James G, Mueller, Luciano

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Orientation of Peptide Fragments from Sos Proteins Bound to the N-Terminal SH3 Domain of Grb2 Determined by NMR Spectroscopy von Wittekind, Michael, Mapelli, Claudio, Farmer, Bennett T, Suen, Ki-Ling, Goldfarb, Valentina, Tsao, Jonglin, Lavoie, Thomas, Barbacid, Mariano, Meyers, Chester A, Mueller, Luciano

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Characterization of NADP + binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes von Constantine, Keith L, Mueller, Luciano, Goldfarb, Valentina, Wittekind, Michael, Metzler, William J, Yanchunas, Joseph, Robertson, James G, Malley, Mary F, Friedrichs, Mark S, Farmer, Bennett T

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Small Molecule Receptor Protein Tyrosine Phosphatase γ (RPTPγ) Ligands That Inhibit Phosphatase Activity via Perturbation of the Tryptophan–Proline–Aspartate (WPD) Loop von Sheriff, Steven, Beno, Brett R, Zhai, Weixu, Kostich, Walter A, McDonnell, Patricia A, Kish, Kevin, Goldfarb, Valentina, Gao, Mian, Kiefer, Susan E, Yanchunas, Joseph, Huang, Yanling, Shi, Shuhao, Zhu, Shirong, Dzierba, Carolyn, Bronson, Joanne, Macor, John E, Appiah, Kingsley K, Westphal, Ryan S, O’Connell, Jonathan, Gerritz, Samuel W

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Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibit... von Kim, Soong-Hoon, Constantine, Keith L., Duke, Gerald J., Goldfarb, Valentina, Hunt, John T., Johnson, Stephen, Kish, Kevin, Klei, Herbert E., McDonnell, Patricia A., Metzler, William J., Mueller, Luciano, Poss, Michael A., Fairchild, Craig R., Bhide, Rajeev S.

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Assessing compound binding to the Eg5 motor domain using a thermal shift assay von McDonnell, Patricia A., Yanchunas, Joseph, Newitt, John A., Tao, Li, Kiefer, Susan E., Ortega, Marie, Kut, Stephanie, Burford, Neil, Goldfarb, Valentina, Duke, Gerald J., Shen, Henry, Metzler, William, Doyle, Michael, Chen, Zhong, Tarby, Christine, Borzilleri, Robert, Vaccaro, Wayne, Gottardis, Marco, Lu, Songfeng, Crews, Donald, Kim, Kyoung, Lombardo, Louis, Roussell, Deborah L.

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Discovery and Development of 5-[(5S,9R)-9- (4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1- methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non- 7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101... von Potin, Dominique, Launay, Michele, Monatlik, Francoise, Malabre, Patrice, Fabreguettes, Maud, Fouquet, Andre, Maillet, Magali, Nicolai, Eric, Dorgeret, Loïc, Chevallier, François, Besse, Dominique, Dufort, Monique, Caussade, François, Ahmad, Syed Z, Stetsko, Dawn K, Skala, Stacey, Davis, Patricia M, Balimane, Praveen, Patel, Karishma, Yang, Zheng, Marathe, Punit, Postelneck, Jennifer, Townsend, Robert M, Goldfarb, Valentina, Sheriff, Steven, Einspahr, Howard, Kish, Kevin, Malley, Mary F, DiMarco, John D, Gougoutas, Jack Z, Kadiyala, Pathanjali, Cheney, Daniel L, Tejwani, Ravindra W, Murphy, Denette K, Mcintyre, Kim W, Yang, Xiaoxia, Chao, Sam, Leith, Leslie, Xiao, Zili, Mathur, Arvind, Chen, Bang-Chi, Wu, Daugh-Rurng, Traeger, Sarah C, McKinnon, Murray, Barrish, Joel C, Robl, Jeffrey A, Iwanowicz, Edwin J, Suchard, Suzanne J, Dhar, T. G. Murali

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Multiple and Single Binding Modes of Fragment-Like Kinase Inhibitors Revealed by Molecular Modeling, Residue Type-Selective Protonation, and Nuclear Overhauser Effects von Constantine, Keith L, Mueller, Luciano, Metzler, William J, McDonnell, Patricia A, Todderud, Gordon, Goldfarb, Valentina, Fan, Yi, Newitt, John A, Kiefer, Susan E, Gao, Mian, Tortolani, David, Vaccaro, Wayne, Tokarski, John

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NMR Structure of a Potent Small Molecule Inhibitor Bound to Human Keratinocyte Fatty Acid-Binding Protein von McDonnell, Patricia A, Constantine, Keith L, Goldfarb, Valentina, Johnson, Stephen R, Sulsky, Richard, Magnin, David R, Robl, Jeffrey A, Caulfield, Thomas J, Parker, Rex A, Taylor, David S, Adam, Leonard P, Metzler, William J, Mueller, Luciano, Farmer, Bennett T

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Electrogenic Cl-Pump in Acetabularia von Gradmann, D., Tittor, J., Goldfarb, Valentina

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Cloning, purification, crystallization and preliminary X-ray analysis of the catalytic domain of human receptor-like protein tyrosine phosphatase [gamma] in three different crystal... von Kish, Kevin, McDonnell, Patricia A, Goldfarb, Valentina, Gao, Mian, Metzler, William J, Langley, David R, Bryson, James W, Kiefer, Susan E, Carpenter, Brian, Kostich, Walter A, Westphal, Ryan S, Sheriff, Steven

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Cloning, purification, crystallization and preliminary X-ray analysis of the catalytic domain of human receptor-like protein tyrosine phosphatase γ in three different crystal forms... von Kish, Kevin, McDonnell, Patricia A., Goldfarb, Valentina, Gao, Mian, Metzler, William J., Langley, David R., Bryson, James W., Kiefer, Susan E., Carpenter, Brian, Kostich, Walter A., Westphal, Ryan S., Sheriff, Steven

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Structural and functional characterization of CFE88: Evidence that a conserved and essential bacterial protein is a methyltransferase von Constantine, Keith L., Krystek, Stanley R., Healy, Matthew D., Doyle, Michael L., Siemers, Nathan O., Thanassi, Jane, Yan, Ning, Xie, Dianlin, Goldfarb, Valentina, Yanchunas, Joseph, Tao, Li, Dougherty, Brian A., Farmer, Bennett T.

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Incorporation of 1H/13C/15N-{Ile, Leu, Val} into a Perdeuterated, 15N-Labeled Protein:  Potential in Structure Determination of Large Proteins by NMR von Metzler, William J., Wittekind, Michael, Goldfarb, Valentina, Mueller, Luciano, Farmer, Bennett T.

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Incorporation of 1 H/ 13 C/ 15 N-{Ile, Leu, Val} into a Perdeuterated, 15 N-Labeled Protein:  Potential in Structure Determination of Large Proteins by NMR von Metzler, William J., Wittekind, Michael, Goldfarb, Valentina, Mueller, Luciano, Farmer, Bennett T.

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Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shif... von Wittekind, Michael, Mapelli, Claudio, Lee, Ving, Goldfarb, Valentina, Friedrichs, Mark S., Meyers, Chester A., Mueller, Luciano

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Production and Characterization of an Antibody Fv Fragment 15N-Labeled in the V L Domain Only von Goldfarb, Valentina, Wittekind, Michael, Jeffrey, Philip D., Mueller, Luciano, Constantine, Keith L.

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Characterization of the backbone dynamics of an anti‐digoxin antibody V L domain by inverse detected 1 H– 15 N NMR: Comparisons with X‐ray data for the Fab von Constantine, Keith L., Friedrichs, Mark S., Goldfarb, Valentina, Jeffrey, Philip D., Sheriff, Steven, Mueller, Luciano

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