VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium von Bagaev, Dmitry V, Vroomans, Renske M A, Samir, Jerome, Stervbo, Ulrik, Rius, Cristina, Dolton, Garry, Greenshields-Watson, Alexander, Attaf, Meriem, Egorov, Evgeny S, Zvyagin, Ivan V, Babel, Nina, Cole, David K, Godkin, Andrew J, Sewell, Andrew K, Kesmir, Can, Chudakov, Dmitriy M, Luciani, Fabio, Shugay, Mikhail

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Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity von Scurr, Martin J., Lippiatt, George, Capitani, Lorenzo, Bentley, Kirsten, Lauder, Sarah N., Smart, Kathryn, Somerville, Michelle S., Rees, Tara, Stanton, Richard J., Gallimore, Awen, Hindley, James P., Godkin, Andrew

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Interleukin‐6 limits influenza‐induced inflammation and protects against fatal lung pathology von Lauder, Sarah N., Jones, Emma, Smart, Kathryn, Bloom, Anja, Williams, Anwen S., Hindley, James P., Ondondo, Beatrice, Taylor, Philip R., Clement, Mathew, Fielding, Ceri, Godkin, Andrew J., Jones, Simon A., Gallimore, Awen M.

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More tricks with tetramers: a practical guide to staining T cells with peptide–MHC multimers von Dolton, Garry, Tungatt, Katie, Lloyd, Angharad, Bianchi, Valentina, Theaker, Sarah M., Trimby, Andrew, Holland, Christopher J., Donia, Marco, Godkin, Andrew J., Cole, David K., Thor Straten, Per, Peakman, Mark, Svane, Inge Marie, Sewell, Andrew K.

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CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer von Clarke, Sarah L, Betts, Gareth J, Plant, Andrea, Wright, Kate L, El-Shanawany, Tariq M, Harrop, Richard, Torkington, Jared, Rees, Brian I, Williams, Geraint T, Gallimore, Awen M, Godkin, Andrew J

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The Ussing chamber system for measuring intestinal permeability in health and disease von Thomson, Amanda, Smart, Kathryn, Somerville, Michelle S, Lauder, Sarah N, Appanna, Gautham, Horwood, James, Sunder Raj, Lawrence, Srivastava, Brijesh, Durai, Dharmaraj, Scurr, Martin J, Keita, Åsa V, Gallimore, Awen M, Godkin, Andrew

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Resolution of persistent SARS-CoV-2 infection with prolonged intravenous remdesivir and vaccination in a patient post CAR-T von Ambati, Sai, Ali, Bazga, Seddon, Owen, Godkin, Andrew, Scurr, Martin, Moore, Catherine, Rowntree, Clare, Underwood, Jonathan

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Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity von Chen, Yuan, Mason, Georgina H., Scourfield, D. Oliver, Greenshields-Watson, Alexander, Haigh, Tracey A., Sewell, Andrew K., Long, Heather M., Gallimore, Awen M., Rizkallah, Pierre, MacLachlan, Bruce J., Godkin, Andrew

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Structural basis for ineffective T‐cell responses to MHC anchor residue‐improved “heteroclitic” peptides von Madura, Florian, Rizkallah, Pierre J., Holland, Christopher J., Fuller, Anna, Bulek, Anna, Godkin, Andrew J., Schauenburg, Andrea J., Cole, David K., Sewell, Andrew K.

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CD4+ T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features von Greenshields-Watson, Alexander, Attaf, Meriem, MacLachlan, Bruce J., Whalley, Thomas, Rius, Cristina, Wall, Aaron, Lloyd, Angharad, Hughes, Hywel, Strange, Kathryn E., Mason, Georgina H., Schauenburg, Andrea J., Hulin-Curtis, Sarah L., Geary, James, Chen, Yuan, Lauder, Sarah N., Smart, Kathryn, Vijaykrishna, Dhanasekaran, Grau, Miguel L., Shugay, Mikhail, Andrews, Robert, Dolton, Garry, Rizkallah, Pierre J., Gallimore, Awen M., Sewell, Andrew K., Godkin, Andrew J., Cole, David K.

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Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs von Tungatt, Katie, Bianchi, Valentina, Crowther, Michael D, Powell, Wendy E, Schauenburg, Andrea J, Trimby, Andrew, Donia, Marco, Miles, John J, Holland, Christopher J, Cole, David K, Godkin, Andrew J, Peakman, Mark, Straten, Per Thor, Svane, Inge Marie, Sewell, Andrew K, Dolton, Garry

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T-Cell Trafficking Facilitated by High Endothelial Venules Is Required for Tumor Control after Regulatory T-Cell Depletion von HINDLEY, James P, JONES, Emma, PRICE, David A, AGER, Ann, GODKIN, Andrew J, GALLIMORE, Awen M, SMART, Kathryn, BRIDGEMAN, Hayley, LAUDER, Sarah N, ONDONDO, Beatrice, CUTTING, Scott, LADELL, Kristin, WYNN, Katherine K, WITHERS, David

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Interleukin-6 is crucial for recall of influenza-specific memory CD4 T cells von Longhi, Maria Paula, Wright, Kate, Lauder, Sarah N, Nowell, Mari A, Jones, Gareth W, Godkin, Andrew J, Jones, Simon A, Gallimore, Awen M

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Regulatory T Cells Play a Role in Determining the Tumourigenicity of the Intestinal Stem Cell Niche von Padilha, Ana, Jones, Emma, Cutting, Scott, Godkin, Andrew, Gallimore, Awen, Parry, Lee

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Pouring petrol on the flames: Using oncolytic virotherapies to enhance tumour immunogenicity von Teijeira Crespo, Alicia, Burnell, Stephanie, Capitani, Lorenzo, Bayliss, Rebecca, Moses, Elise, Mason, Georgina H., Davies, James A., Godkin, Andrew J., Gallimore, Awen M., Parker, Alan L.

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Analysis of the T-Cell Receptor Repertoires of Tumor-Infiltrating Conventional and Regulatory T Cells Reveals No Evidence for Conversion in Carcinogen-Induced Tumors von HINDLEY, James P, FERREIRA, Cristina, DYSON, Julian, GALLIMORE, Awen, JONES, Emma, LAUDER, Sarah N, LADELL, Kristin, WYNN, Katherine K, BETTS, Gareth J, SINGH, Yogesh, PRICE, David A, GODKIN, Andrew J

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Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence von Clement, Mathew, Marsden, Morgan, Stacey, Maria A, Abdul-Karim, Juneid, Gimeno Brias, Silvia, Costa Bento, Diana, Scurr, Martin J, Ghazal, Peter, Weaver, Casey T, Carlesso, Gianluca, Clare, Simon, Jones, Simon A, Godkin, Andrew, Jones, Gareth W, Humphreys, Ian R

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T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions von Cole, David K., Miles, Kim M., Madura, Florian, Holland, Christopher J., Schauenburg, Andrea J.A., Godkin, Andrew J., Bulek, Anna M., Fuller, Anna, Akpovwa, Hephzibah J.E., Pymm, Phillip G., Liddy, Nathaniel, Sami, Malkit, Li, Yi, Rizkallah, Pierre J., Jakobsen, Bent K., Sewell, Andrew K.

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Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers von Lissina, Anna, Ladell, Kristin, Skowera, Ania, Clement, Matthew, Edwards, Emily, Seggewiss, Ruth, van den Berg, Hugo A., Gostick, Emma, Gallagher, Kathleen, Jones, Emma, Melenhorst, J. Joseph, Godkin, Andrew J., Peakman, Mark, Price, David A., Sewell, Andrew K., Wooldridge, Linda

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In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope von Anderson, Robert P., Degano, Pilar, Godkin, Andrew J., Jewell, Derek P., Hill, Adrian V.S.

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