In vitro and in vivo P-glycoprotein transport characteristics of rivaroxaban von Gnoth, Mark Jean, Buetehorn, Ulf, Muenster, Uwe, Schwarz, Thomas, Sandmann, Steffen

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Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites von Swift, Brandon, Nebot, Noelia, Lee, Jin Kyung, Han, Tianxiang, Proctor, William R, Thakker, Dhiren R, Lang, Dieter, Radtke, Martin, Gnoth, Mark J, Brouwer, Kim L R

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Human Milk Oligosaccharides Are Minimally Digested In Vitro von Gnoth, Mark J., Kunz, Clemens, Kinne-Saffran, Evamaria, Rudloff, Silvia

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Immunocapture LC–MS(/MS) assays for biotherapeutic and biomarker proteins: the European Bioanalysis Forum continuing discussions on scientific and regulatory challenges von Barfield, Matthew, Blackburn, Michael, Blattmann, Peter, Ingelse, Benno, Jordan, Gregor, Fusetti, Fabrizia, Gnoth, Mark J, Sporring, Sune H, Love, Iain, Muccio, Stephane, de Merbel, Nico van, Wheller, Rob, Wilson, Amanda, Timmerman, Philip

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Determination of Riociguat and its Major Human Metabolite M-1 in Human Plasma by Stable-Isotope Dilution LCMS/MS von Gnoth, Mark-Jean, Hopfe, Peter-Michael, Czembor, Waldemar

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Inhaled Agonists of Soluble Guanylate Cyclase Induce Selective Pulmonary Vasodilation von Evgenov, Oleg V, Kohane, Daniel S, Bloch, Kenneth D, Stasch, Johannes-Peter, Volpato, Gian P, Bellas, Evangelia, Evgenov, Natalia V, Buys, Emmanuel S, Gnoth, Mark J, Graveline, Amanda R, Liu, Rong, Hess, Dean R, Langer, Robert, Zapol, Warren M

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Soluble guanylate cyclase activator reverses acute pulmonary hypertension and augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs von EVGENOV, Oleg V, ICHINOSE, Fumito, EVGENOV, Natalia V, GNOTH, Mark J, FALKOWSKI, George E, YUCHIAO CHANG, BLOCH, Kenneth D, ZAPOL, Warren M

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Determination of Nifurtimox in Dog Plasma by Stable-Isotope Dilution LC–MS/MS von Gnoth, Mark-Jean, Hopfe, Peter-Michael, Thuss, Uwe

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Characterization of Substrates and Inhibitors for the In Vitro Assessment of Bcrp Mediated Drug–Drug Interactions von Muenster, Uwe, Grieshop, Birgit, Ickenroth, Karsten, Gnoth, Mark Jean

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Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling von DUMITRASCU, Rio, WEISSMANN, Norbert, SCHERMULY, Ralph Theo, GHOFRANI, Hossein Ardeschir, DONY, Eva, BEUERLEIN, Knut, SCHMIDT, Harald, STASCH, Johannes-Peter, GNOTH, Mark Jean, SEEGER, Werner, GRIMMINGER, Friedrich

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Pharmacokinetics of the Soluble Guanylate Cyclase Activator Cinaciguat in Individuals With Hepatic Impairment von Frey, Reiner, Scheerans, Christian, Blunck, Martin, Mück, Wolfgang, Gnoth, Mark Jean, Unger, Sigrun, Schmidt, Anja, Wensing, Georg

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Design and Synthesis of Potent and Selective Azaindole-Based Rho Kinase (ROCK) Inhibitors von Schirok, Hartmut, Kast, Raimund, Figueroa-Pérez, Santiago, Bennabi, Samir, Gnoth, Mark J., Feurer, Achim, Heckroth, Heike, Thutewohl, Michael, Paulsen, Holger, Knorr, Andreas, Hütter, Joachim, Lobell, Mario, Münter, Klaus, Geiß, Volker, Ehmke, Heimo, Lang, Dieter, Radtke, Martin, Mittendorf, Joachim, Stasch, Johannes-Peter

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Volume to dissolve applied dose (VDAD) and apparent dissolution rate (ADR): Tools to predict in vivo bioavailability from orally applied drug suspensions von Muenster, Uwe, Pelzetter, Christian, Backensfeld, Thomas, Ohm, Andreas, Kuhlmann, Thomas, Mueller, Hartwig, Lustig, Klemens, Keldenich, Jörg, Greschat, Susanne, Göller, Andreas H., Gnoth, Mark Jean

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Investigations of the in Vitro Transport of Human Milk Oligosaccharides by a Caco-2 Monolayer Using a Novel High Performance Liquid Chromatography-Mass Spectrometry Technique von Gnoth, Mark J., Rudloff, Silvia, Kunz, Clemens, Kinne, Rolf K.H.

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Transporter tandems: precise tools for normalizing active transporter in the plasma membrane von Tschirka, Julia, Bach, Markus, Kisis, Ilmars, Lemmen, Julia, Gnoth, Mark Jean, Gründemann, Dirk

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Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics von Hillisch, Alexander, Gericke, Kersten M, Allerheiligen, Swen, Roehrig, Susanne, Schaefer, Martina, Tersteegen, Adrian, Schulz, Simone, Lienau, Philip, Gnoth, Mark, Puetter, Vera, Hillig, Roman C, Heitmeier, Stefan

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In Vitro to In Vivo Comparison of the Substrate Characteristics of Sorafenib Tosylate toward P-Glycoprotein von GNOTH, M. J, SANDMANN, S, ENGEL, K, RADTKE, M

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Perspective on LC-MS(/MS) for biotherapeutic and biomarker proteins in research and regulated Bioanalysis: a consolidation of more than a decade of experience across the European B... von de Merbel, Nico van, Gnoth, Mark Jean, Wilson, Amanda, Blattmann, Peter, Ingelse, Benno, Jordan, Gregor, Fusetti, Fabrizia, Blackburn, Michael, Sporring, Sune Hove, Love, Iain, Muccio, Stephane, Barfield, Matthew, Wheller, Rob, Timmerman, Philip

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Perspective on LC-MS(/MS) for biotherapeutic and biomarker proteins in research and regulated Bioanalysis: a consolidation of more than a decade of experience across the European B... von Wilson, Amanda, Gnoth, Mark Jean, de Merbel, Nico van, Blattmann, Peter, Ingelse, Benno, Jordan, Gregor, Fusetti, Fabrizia, Blackburn, Michael, Sporring, Sune Hove, Love, Iain, Muccio, Stephane, Barfield, Matthew, Wheller, Rob, Timmerman, Philip

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The use of surrogate matrices in bioanalytical preclinical safety testing using chromatographic methods: a recommendation from the European Bioanalysis forum von Goodwin, Lee, McDougall, Stuart, Gnoth, Mark Jean, Mascher, Daniel, Ferrari, Luca, Wheller, Robert, Hawthorne, Hayley, Jansat, Josep-Maria, Faber, Joerg, Huber, Peter, Greco, Alessandro, Eggers, Lars F, Sury, Matthias, Karlsson, Jens-Jakob, Sporring, Sune Hove, Globig, Susanne, de Merbel, Nico van, Timmerman, Philip

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