Dissecting Machine-Learning Prediction of Molecular Activity: Is an Applicability Domain Needed for Quantitative Structure–Activity Relationship Models Based on Deep Neural Network... von Liu, Ruifeng, Wang, Hao, Glover, Kyle P, Feasel, Michael G, Wallqvist, Anders

Volltext

General Approach to Estimate Error Bars for Quantitative Structure–Activity Relationship Predictions of Molecular Activity von Liu, Ruifeng, Glover, Kyle P, Feasel, Michael G, Wallqvist, Anders

Volltext

Characterization of Cellular Uptake of Perfluorooctanoate via Organic Anion-Transporting Polypeptide 1A2, Organic Anion Transporter 4, and Urate Transporter 1 for Their Potential R... von Yang, Ching-Hui, Glover, Kyle P., Han, Xing

Volltext

Assessing Deep and Shallow Learning Methods for Quantitative Prediction of Acute Chemical Toxicity von Liu, Ruifeng, Madore, Michael, Glover, Kyle P, Feasel, Michael G, Wallqvist, Anders

Volltext

A novel approach to interrogating the effects of chemical warfare agent exposure using organ-on-a-chip technology and multiomic analysis von Goralski, Tyler D P, Jenkins, Conor C, Angelini, Daniel J, Horsmon, Jennifer R, Dhummakupt, Elizabeth S, Rizzo, Gabrielle M, Simmons, Brooke L, Liem, Alvin T, Roth, Pierce A, Karavis, Mark A, Hill, Jessica M, Sekowski, Jennifer W, Glover, Kyle P

Volltext

Synergistic Gene Expression Signature Observed in TK6 Cells upon Co-Exposure to UVC-Irradiation and Protein Kinase C-Activating Tumor Promoters von Glover, Kyle P, Chen, Zhongqiang, Markell, Lauren K, Han, Xing

Volltext

Organic anion transporting polypeptide (Oatp) 1a1-mediated perfluorooctanoate transport and evidence for a renal reabsorption mechanism of Oatp1a1 in renal elimination of perfluoro... von Yang, Ching-Hui, Glover, Kyle P., Han, Xing

Volltext

Assessment of zebrafish embryo photomotor response sensitivity and phase‐specific patterns following acute‐ and long‐duration exposure to neurotoxic chemicals and chemical weapon p... von Carbaugh, Chance M., Widder, Mark W., Phillips, Christopher S., Jackson, David A., DiVito, Valerie T., Schalie, William H., Glover, Kyle P.

Volltext

Protein kinase C-activating tumor promoters modulate the DNA damage response in UVC-irradiated TK6 cells von Glover, Kyle P., Markell, Lauren K., Donner, E. Maria, Han, Xing

Volltext

CAGm: a repository of germline microsatellite variations in the 1000 genomes project von Kinney, Nicholas, Titus-Glover, Kyle, Wren, Jonathan D, Varghese, Robin T, Michalak, Pawel, Liao, Han, Anandakrishnan, Ramu, Pulenthiran, Arichanah, Kang, Lin, Garner, Harold R

Volltext

An Integrated Multi-Omics Analysis Defines Key Pathway Alterations in a Diet-Induced Obesity Mouse Model von Sundekilde, Ulrik K, Yde, Christian C, Honore, Anders H, Caverly Rae, Jessica M, Burns, Frank R, Mukerji, Pushkor, Mawn, Michael P, Stenman, Lotta, Dragan, Yvonne, Glover, Kyle, Jensen, Henrik M

Volltext

Cryopreserved Hepatocytes from Rainbow Trout (Oncorhynchus mykiss): A Validation Study to Support Their Application in Bioaccumulation Assessment von Mingoia, Robert T, Glover, Kyle P, Nabb, Diane L, Yang, Ching-Hui, Snajdr, Suzanne I, Han, Xing

Volltext

MACHINES MAKE MISTAKES TOO: PLANNING FOR AI LIABILITY IN CONTRACTING von Sayre, Mark A, Glover, Kyle

Volltext

Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity von Clippinger, Amy J., Allen, David, Behrsing, Holger, BéruBé, Kelly A., Bolger, Michael B., Casey, Warren, DeLorme, Michael, Gaça, Marianna, Gehen, Sean C., Glover, Kyle, Hayden, Patrick, Hinderliter, Paul, Hotchkiss, Jon A., Iskandar, Anita, Keyser, Brian, Luettich, Karsta, Ma-Hock, Lan, Maione, Anna G., Makena, Patrudu, Melbourne, Jodie, Milchak, Lawrence, Ng, Sheung P., Paini, Alicia, Page, Kathryn, Patlewicz, Grace, Prieto, Pilar, Raabe, Hans, Reinke, Emily N., Roper, Clive, Rose, Jane, Sharma, Monita, Spoo, Wayne, Thorne, Peter S., Wilson, Daniel M., Jarabek, Annie M.

Volltext

Mind the gaps: Prioritizing activities to meet regulatory needs for acute systemic lethality von Sullivan, Kristie, Allen, David G, Clippinger, Amy J, Wilson, Daniel M, Edwards, Stephen W, Glover, Kyle, Mansouri, Kamel, Settivari, Raja, Wijeyesakere, Sanjeeva J, Casey, Warren

Volltext

Principles and procedures for assessment of acute toxicity incorporating in silico methods von Zwickl, Craig M., Graham, Jessica C., Jolly, Robert A., Bassan, Arianna, Ahlberg, Ernst, Amberg, Alexander, Anger, Lennart T., Beilke, Lisa, Bellion, Phillip, Brigo, Alessandro, Burleigh-Flayer, Heather, Cronin, Mark T.D., Devlin, Amy A., Fish, Trevor, Glowienke, Susanne, Gromek, Kamila, Karmaus, Agnes L., Kemper, Ray, Kulkarni, Sunil, Lo Piparo, Elena, Madia, Federica, Martin, Matthew, Masuda-Herrera, Melisa, McAtee, Britt L., Mestres, Jordi, Milchak, Lawrence, Moudgal, Chandrika, Mumtaz, Moiz, Muster, Wolfgang, Neilson, Louise, Patlewicz, Grace, Paulino, Alexandre, Roncaglioni, Alessandra, Ruiz, Patricia, Szabo, David T., Valentin, Jean-Pierre, Vardakou, Ioanna, Woolley, David, Myatt, Glenn J.

Volltext

Pathway-Based Predictive Approaches for Non-Animal Assessment of Acute Inhalation Hazard Determination von Clippinger, Amy J., Allen, David, Behrsing, Holger, BéruBé, Kelly A., Bolger, Michael B., DeLorme, Michael, Gaça, Marianna, Gehen, Sean C., Glover, Kyle, Hayden, Patrick, Hinderliter, Paul, Hotchkiss, Jon A., Iskandar, Anita, Keyser, Brain, Luettich, Karsta, Ma-Hock, Lan, Maione, Anna, Makena, Patrudu, Melbourne, Jodie, Milchak, Lawrence, Ng, Sheung P., Paini, Alicia, Page, Kathryn, Patlewicz, Grace, Prieto, Pilar, Raabe, Hans, Reinke, Emily, Roper, Clive, Rose, Jane, Sharma, Monita, Spoo, Wayne, Thorne, Peter S., Wilson, Daniel M., Jarabek, Annie M.

Volltext

Synergistic Gene Expression Signature Observed in TK6 Cells upon Co-Exposure to UVC-Irradiation and Protein Kinase C-Activating Tumor Promoters: e0139850 von Glover, Kyle P, Chen, Zhongqiang, Markell, Lauren K, Han, Xing

Volltext

Capturing the Advantages of IBB: Labor Negotiations at Harvard von GLOVER, KYLE, HARRIS, E. ASHLEY

Volltext

A novel approach to interrogating the effects of chemical warfare agent exposure using organ-on-a-chip technology and multiomic analysis von Tyler D P Goralski, Conor C Jenkins, Daniel J Angelini, Jennifer R Horsmon, Elizabeth S Dhummakupt, Gabrielle M Rizzo, Brooke L Simmons, Alvin T Liem, Pierce A Roth, Mark A Karavis, Jessica M Hill, Jennifer W Sekowski, Kyle P Glover

Volltext