DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis von Mowbray, Charles E, Braillard, Stéphanie, Glossop, Paul A, Whitlock, Gavin A, Jacobs, Robert T, Speake, Jason, Pandi, Bharathi, Nare, Bakela, Maes, Louis, Yardley, Vanessa, Freund, Yvonne, Wall, Richard J, Carvalho, Sandra, Bello, Davide, Van den Kerkhof, Magali, Caljon, Guy, Gilbert, Ian H, Corpas-Lopez, Victoriano, Lukac, Iva, Patterson, Stephen, Zuccotto, Fabio, Wyllie, Susan

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Inhibition of TRPM8 Channels Reduces Pain in the Cold Pressor Test in Humans von Winchester, Wendy J., Gore, Katrina, Glatt, Sophie, Petit, Wendy, Gardiner, Jennifer C., Conlon, Kelly, Postlethwaite, Michael, Saintot, Pierre-Philippe, Roberts, Sonia, Gosset, James R., Matsuura, Tomomi, Andrews, Mark D., Glossop, Paul A., Palmer, Michael J., Clear, Nicola, Collins, Susie, Beaumont, Kevin, Reynolds, David S.

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Novel Amino-pyrazole Ureas with Potent In Vitro and In Vivo Antileishmanial Activity von Mowbray, Charles E, Braillard, Stéphanie, Speed, William, Glossop, Paul A, Whitlock, Gavin A, Gibson, Karl R, Mills, James E. J, Brown, Alan D, Gardner, J. Mark F, Cao, Yafeng, Hua, Wen, Morgans, Garreth L, Feijens, Pim-Bart, Matheeussen, An, Maes, Louis J

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Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin‑2 Receptor: Structure–Activity Relationships and Optimization von Zirimwabagabo, Jean-Olivier, Jailani, Ameera B. A, Avgoustou, Paris, Tozer, Matthew J, Gibson, Karl R, Glossop, Paul A, Mills, James E. J, Porter, Roderick A, Blaney, Paul, Wang, Ning, Skerry, Timothy M, Richards, Gareth O, Harrity, Joseph P. A

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Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain von Andrews, Mark D, af Forselles, Kerry, Beaumont, Kevin, Galan, Sébastien R. G, Glossop, Paul A, Grenie, Mathilde, Jessiman, Alan, Kenyon, Amy S, Lunn, Graham, Maw, Graham, Owen, Robert M, Pryde, David C, Roberts, Dannielle, Tran, Thien Duc

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A formal synthesis of (+)-lactacystin from 4-hydroxyproline von Mycock, David K., Glossop, Paul A., Lewis, William, Hayes, Christopher J.

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Inhalation by design: novel ultra-long-acting β(2)-adrenoreceptor agonists for inhaled once-daily treatment of asthma and chronic obstructive pulmonary disease that utilize a sulfo... von Glossop, Paul A, Lane, Charlotte A L, Price, David A, Bunnage, Mark E, Lewthwaite, Russell A, James, Kim, Brown, Alan D, Yeadon, Michael, Perros-Huguet, Christelle, Trevethick, Michael A, Clarke, Nicholas P, Webster, Robert, Jones, Rhys M, Burrows, Jane L, Feeder, Neil, Taylor, Stefan C J, Spence, Fiona J

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Inhalation by Design: Novel Ultra-Long-Acting β2-Adrenoreceptor Agonists for Inhaled Once-Daily Treatment of Asthma and Chronic Obstructive Pulmonary Disease That Utilize a Sulfona... von Glossop, Paul A, Lane, Charlotte A. L, Price, David A, Bunnage, Mark E, Lewthwaite, Russell A, James, Kim, Brown, Alan D, Yeadon, Michael, Perros-Huguet, Christelle, Trevethick, Michael A, Clarke, Nicholas P, Webster, Robert, Jones, Rhys M, Burrows, Jane L, Feeder, Neil, Taylor, Stefan C. J, Spence, Fiona J

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Pyridine-N-Oxide as a Mild Reoxidant Which Transforms Osmium-Catalyzed Oxidative Cyclization von Donohoe, Timothy J, Wheelhouse (née Gosby), Katherine M.P, Lindsay-Scott, Peter J, Glossop, Paul A, Nash, Ian A, Parker, Jeremy S

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Stereoselective Synthesis of Pyrrolidines: Catalytic Oxidative Cyclizations Mediated by Osmium von Donohoe, Timothy J., Churchill, Gwydion H., Wheelhouse (née Gosby), Katherine M. P., Glossop, Paul A.

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Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin‑2 Receptor von Avgoustou, Paris, Jailani, Ameera B. A, Zirimwabagabo, Jean-Olivier, Tozer, Matthew J, Gibson, Karl R, Glossop, Paul A, Mills, James E. J, Porter, Roderick A, Blaney, Paul, Bungay, Peter J, Wang, Ning, Shaw, Alice P, Bigos, Kamilla J. A, Holmes, Joseph L, Warrington, Jessica I, Skerry, Timothy M, Harrity, Joseph P. A, Richards, Gareth O

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Identification of Type-II Inhibitors Using Kinase Structures von Lovering, Frank, McDonald, Joseph, Whitlock, Gavin A., Glossop, Paul A., Phillips, Chris, Bent, Andrew, Sabnis, Yogesh, Ryan, Mark, Fitz, Lori, Lee, Julie, Chang, Jeanne S., Han, Seungil, Kurumbail, Ravi, Thorarensen, Atli

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Design and synthesis of long acting inhaled corticosteroids for the treatment of asthma von Millan, David S., Ballard, Stephen A., Chunn, Sara, Dybowski, Joseph A., Fulton, Craig K., Glossop, Paul A., Guillabert, Edouard, Hewson, Christopher A., Jones, Rhys M., Lamb, David J., Napier, Carolyn M., Payne-Cook, Toby A., Renery, Emmanuelle R., Selby, Matthew D., Tutt, Michelle F., Yeadon, Michael

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Osmium‐Mediated Oxidative Cyclizations: A Study into the Range of Initiators That Facilitate Cyclization von Donohoe, Timothy J., Wheelhouse (née Gosby), Katherine M. P., Lindsay‐Scott, Peter J., Churchill, Gwydion H., Connolly, Matthew J., Butterworth, Sam, Glossop, Paul A.

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The discovery of long acting β2-adrenoreceptor agonists von BROWN, Alan D, BUNNAGE, Mark E, TREVETHICK, Mike, WEBSTER, Rob, GLOSSOP, Paul A, JAMES, Kim, JONES, Rhys, LANE, Charlotte A. L, LEWTHWAITE, Russell A, MANTELL, Simon, PERROS-HUGUET, Christelle, PRICE, David A

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Development of a Scaleable Synthesis of a Geminal Dimethyl Tertiary Amine as an Inhaled Muscarinic Antagonist for the Treatment of COPD von Dillon, Barry R, Roberts, Dannielle F, Entwistle, David A, Glossop, Paul A, Knight, Craig J, Laity, Daniel A, James, Kim, Praquin, Celine F, Strang, Ross S, Watson, Christine A. L

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The discovery of adamantyl-derived, inhaled, long acting β2-adrenoreceptor agonists von BROWN, Alan D, BUNNAGE, Mark E, TREVETHICK, Mike, WEBSTER, Rob, GLOSSOP, Paul A, JAMES, Kim, JONES, Rhys, LANE, Charlotte A. L, LEWTHWAITE, Russell A, MANTELL, Simon, PERROS-HUGUET, Christelle, PRICE, David A

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The discovery of adamantyl-derived, inhaled, long acting beta(2)-adrenoreceptor agonists von Brown, Alan D, Bunnage, Mark E, Glossop, Paul A, James, Kim, Jones, Rhys, Lane, Charlotte A L, Lewthwaite, Russell A, Mantell, Simon, Perros-Huguet, Christelle, Price, David A, Trevethick, Mike, Webster, Rob

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The discovery of indole-derived long acting β2-adrenoceptor agonists for the treatment of asthma and COPD von BROWN, Alan D, BUNNAGE, Mark E, WEBSTER, Rob, GLOSSOP, Paul A, HOLBROOK, Mark, JONES, Rhys D, LANE, Charlotte A. L, LEWTHWAITE, Russell A, MANTELL, Simon, PERROS-HUGUET, Christelle, PRICE, David A

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A highly selective method for 11β-OH protection of steroidal 11β, 17α-diols von Glossop, Paul A., Hoogenraad, Marcel, Peakman, Torren M., Roberts, Dannielle F.

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