Structural Classification of Toxic Amyloid Oligomers von Glabe, Charles G.

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Common mechanisms of amyloid oligomer pathogenesis in degenerative disease von Glabe, Charles G.

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Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar olig... von Sosna, Justyna, Philipp, Stephan, Albay, 3rd, Ricardo, Reyes-Ruiz, Jorge Mauricio, Baglietto-Vargas, David, LaFerla, Frank M, Glabe, Charles G

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Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction von Tomic, Jennifer L, Pensalfini, Anna, Head, Elizabeth, Glabe, Charles G

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Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis von Glabe, Charles G, Kayed, Rakez

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Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates von Liu, Cong, Zhao, Minglei, Jiang, Lin, Cheng, Pin-Nan, Park, Jiyong, Sawaya, Michael R., Pensalfini, Anna, Gou, Dawei, Berk, Arnold J., Glabe, Charles G., Nowick, James, Eisenberg, David

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Structure-based inhibitors of amyloid beta core suggest a common interface with tau von Griner, Sarah L, Seidler, Paul, Bowler, Jeannette, Murray, Kevin A, Yang, Tianxiao Peter, Sahay, Shruti, Sawaya, Michael R, Cascio, Duilio, Rodriguez, Jose A, Philipp, Stephan, Sosna, Justyna, Glabe, Charles G, Gonen, Tamir, Eisenberg, David S

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Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers von Demuro, Angelo, Mina, Erene, Kayed, Rakez, Milton, Saskia C., Parker, Ian, Glabe, Charles G.

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Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis von Kayed, Rakez, Head, Elizabeth, Thompson, Jennifer L., McIntire, Theresa M., Milton, Saskia C., Cotman, Carl W., Glabe, Charles G.

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Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques von Pensalfini, Anna, Albay, Ricardo, Rasool, Suhail, Wu, Jessica W, Hatami, Asa, Arai, Hiromi, Margol, Lawrence, Milton, Saskia, Poon, Wayne W, Corrada, Maria M, Kawas, Claudia H, Glabe, Charles G

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Permeabilization of Lipid Bilayers Is a Common Conformation-dependent Activity of Soluble Amyloid Oligomers in Protein Misfolding Diseases von Kayed, Rakez, Sokolov, Yuri, Edmonds, Brian, McIntire, Theresa M, Milton, Saskia C, Hall, James E, Glabe, Charles G

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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers von Kayed, Rakez, Head, Elizabeth, Sarsoza, Floyd, Saing, Tommy, Cotman, Carl W, Necula, Mihaela, Margol, Lawrence, Wu, Jessica, Breydo, Leonid, Thompson, Jennifer L, Rasool, Suhail, Gurlo, Tatyana, Butler, Peter, Glabe, Charles G

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Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity von Krotee, Pascal, Rodriguez, Jose A, Sawaya, Michael R, Cascio, Duilio, Reyes, Francis E, Shi, Dan, Hattne, Johan, Nannenga, Brent L, Oskarsson, Marie E, Philipp, Stephan, Griner, Sarah, Jiang, Lin, Glabe, Charles G, Westermark, Gunilla T, Gonen, Tamir, Eisenberg, David S

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Soluble and Mature Amyloid Fibrils in Drusen Deposits von Isas, J. Mario, Luibl, Volker, Johnson, Lincoln V, Kayed, Rakez, Wetzel, Ronald, Glabe, Charles G, Langen, Ralf, Chen, Jeannie

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Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization von Teng, Edmond, Taylor, Karen, Bilousova, Tina, Weiland, David, Pham, Thaidan, Zuo, Xiaohong, Yang, Fusheng, Chen, Ping-Ping, Glabe, Charles G, Takacs, Alison, Hoffman, Dennis R, Frautschy, Sally A, Cole, Gregory M

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Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid von Nichol, Kathryn E, Poon, Wayne W, Parachikova, Anna I, Cribbs, David H, Glabe, Charles G, Cotman, Carl W

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Familial Alzheimer's Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-β Peptide von Hatami, Asa, Monjazeb, Sanaz, Milton, Saskia, Glabe, Charles G

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Desmin-Related Cardiomyopathy in Transgenic Mice: A Cardiac Amyloidosis von Sanbe, Atsushi, Osinska, Hanna, Saffitz, Jeffrey E., Glabe, Charles G., Kayed, Rakez, Maloyan, Alina, Robbins, Jeffrey, Olson, Eric N.

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Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril von Wälti, Marielle Aulikki, Ravotti, Francesco, Arai, Hiromi, Glabe, Charles G., Wall, Joseph S., Böckmann, Anja, Güntert, Peter, Meier, Beat H., Riek, Roland

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Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes von Sontag, Emily M., Joachimiak, Lukasz A., Tan, Zhiqun, Tomlinson, Anthony, Housman, David E., Glabe, Charles G., Potkin, Steven G., Frydman, Judith, Thompson, Leslie M.

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