Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis von Wollin, Lutz, Wex, Eva, Pautsch, Alexander, Schnapp, Gisela, Hostettler, Katrin E, Stowasser, Susanne, Kolb, Martin

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Molecular basis of TASL recruitment by the peptide/histidine transporter 1, PHT1 von Custódio, Tânia F., Killer, Maxime, Yu, Dingquan, Puente, Virginia, Teufel, Daniel P., Pautsch, Alexander, Schnapp, Gisela, Grundl, Marc, Kosinski, Jan, Löw, Christian

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Fast native-SAD phasing for routine macromolecular structure determination von Weinert, Tobias, Olieric, Vincent, Waltersperger, Sandro, Panepucci, Ezequiel, Chen, Lirong, Zhang, Hua, Zhou, Dayong, Rose, John, Ebihara, Akio, Kuramitsu, Seiki, Li, Dianfan, Howe, Nicole, Schnapp, Gisela, Pautsch, Alexander, Bargsten, Katja, Prota, Andrea E, Surana, Parag, Kottur, Jithesh, Nair, Deepak T, Basilico, Federica, Cecatiello, Valentina, Pasqualato, Sebastiano, Boland, Andreas, Weichenrieder, Oliver, Wang, Bi-Cheng, Steinmetz, Michel O, Caffrey, Martin, Wang, Meitian

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Ligand recognition and activation of neuromedin U receptor 2 von Zhao, Wenli, Zhang, Wenru, Wang, Mu, Lu, Minmin, Chen, Shutian, Tang, Tingting, Schnapp, Gisela, Wagner, Holger, Brennauer, Albert, Yi, Cuiying, Chu, Xiaojing, Han, Shuo, Wu, Beili, Zhao, Qiang

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The Small Molecule Hesperadin Reveals a Role for Aurora B in Correcting Kinetochore-Microtubule Attachment and in Maintaining the Spindle Assembly Checkpoint von Hauf, Silke, Cole, Richard W., LaTerra, Sabrina, Zimmer, Christine, Schnapp, Gisela, Walter, Rainer, Heckel, Armin, van Meel, Jacques, Rieder, Conly L., Peters, Jan-Michael

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A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein von Schnapp, Gisela, Hoevels, Yvette, Bakker, Remko A., Schreiner, Patrick, Klein, Thomas, Nar, Herbert

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Protons taken hostage: Dynamic H-bond networks of the pH-sensing GPR68 von Kapur, Bhav, Baldessari, Filippo, Lazaratos, Michalis, Nar, Herbert, Schnapp, Gisela, Giorgetti, Alejandro, Bondar, Ana-Nicoleta

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Control of Human Telomere Length by TRF1 and TRF2 von Smogorzewska, Agata, van Steensel, Bas, Bianchi, Alessandro, Oelmann, Stefan, Schaefer, Matthias R., Schnapp, Gisela, de Lange, Titia

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A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state von Schnapp, Gisela, Neubauer, Heike, Büttner, Frank H., Handschuh, Sandra, Lingard, Iain, Heilker, Ralf, Klinder, Klaus, Prestle, Jürgen, Walter, Rainer, Wolff, Michael, Zeeb, Markus, Debaene, Francois, Nar, Herbert, Fiegen, Dennis

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Comparative Analysis of Binding Kinetics and Thermodynamics of Dipeptidyl Peptidase‑4 Inhibitors and Their Relationship to Structure von Schnapp, Gisela, Klein, Thomas, Hoevels, Yvette, Bakker, Remko A, Nar, Herbert

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BI 1291583: a novel selective inhibitor of cathepsin C with superior in vivo profile for the treatment of bronchiectasis von Kreideweiss, Stefan, Schänzle, Gerhard, Schnapp, Gisela, Vintonyak, Viktor, Grundl, Marc A.

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Action of Dipeptidyl Peptidase‐4 Inhibitors on SARS‐CoV‐2 Main Protease von Nar, Herbert, Schnapp, Gisela, Hucke, Oliver, Hardman, Timothy C., Klein, Thomas

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Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists von Apel, Anna-Katharina, Cheng, Robert K.Y., Tautermann, Christofer S., Brauchle, Michael, Huang, Chia-Ying, Pautsch, Alexander, Hennig, Michael, Nar, Herbert, Schnapp, Gisela

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In situ crystallography as an emerging method for structure solution of membrane proteins: the case of CCR2A von Cheng, Robert, Huang, Chia‐Ying, Hennig, Michael, Nar, Herbert, Schnapp, Gisela

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Structural basis of the mechanism and inhibition of a human ceramide synthase von Pascoa, Tomas C, Pike, Ashley C W, Tautermann, Christofer S, Chi, Gamma, Traub, Michael, Quigley, Andrew, Chalk, Rod, Štefanić, Saša, Thamm, Sven, Pautsch, Alexander, Carpenter, Elisabeth P, Schnapp, Gisela, Sauer, David B

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Front Cover: A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein (ChemMedChem... von Schnapp, Gisela, Hoevels, Yvette, Bakker, Remko A., Schreiner, Patrick, Klein, Thomas, Nar, Herbert

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Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule von Tautermann, Christofer S, Binder, Florian, Büttner, Frank H, Eickmeier, Christian, Fiegen, Dennis, Gross, Ulrike, Grundl, Marc A, Heilker, Ralf, Hobson, Scott, Hoerer, Stefan, Luippold, Andreas, Mack, Volker, Montel, Florian, Peters, Stefan, Bhattacharya, Supriyo, Vaidehi, Nagarajan, Schnapp, Gisela, Thamm, Sven, Zeeb, Markus

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A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems von Haberstock, Stefan, Roos, Christian, Hoevels, Yvette, Dötsch, Volker, Schnapp, Gisela, Pautsch, Alexander, Bernhard, Frank

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BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo von Sapkota, Gopal P, Cummings, Lorna, Newell, Felicity S, Armstrong, Christopher, Bain, Jennifer, Frodin, Morten, Grauert, Matthias, Hoffmann, Matthias, Schnapp, Gisela, Steegmaier, Martin, Cohen, Philip, Alessi, Dario R

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Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism von Dahms, Sven O, Schnapp, Gisela, Winter, Martin, Büttner, Frank H, Schlepütz, Marco, Gnamm, Christian, Pautsch, Alexander, Brandstetter, Hans

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