Regioselective Cobalt-Catalyzed Addition of Sulfides to Unactivated Alkenes von Girijavallabhan, Vinay, Alvarez, Carmen, Njoroge, F. George

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Discovery and SAR of hydantoin TACE inhibitors von Yu, Wensheng, Guo, Zhuyan, Orth, Peter, Madison, Vincent, Chen, Lei, Dai, Chaoyang, Feltz, Robert J., Girijavallabhan, Vinay M., Kim, Seong Heon, Kozlowski, Joseph A., Lavey, Brian J., Li, Dansu, Lundell, Daniel, Niu, Xiaoda, Piwinski, John J., Popovici-Muller, Janeta, Rizvi, Razia, Rosner, Kristin E., Shankar, Bandarpalle B., Shih, Neng-Yang, Arshad Siddiqui, M., Sun, Jing, Tong, Ling, Umland, Shelby, Wong, Michael K.C., Yang, De-yi, Zhou, Guowei

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2-(2-Aminothiazol-4-yl)pyrrolidine-based tartrate diamides as potent, selective and orally bioavailable TACE inhibitors von Dai, Chaoyang, Li, Dansu, Popovici-Muller, Janeta, Zhao, Lianyun, Girijavallabhan, Vinay M., Rosner, Kristin E., Lavey, Brian J., Rizvi, Razia, Shankar, Bandarpalle B., Wong, Michael K.C., Guo, Zhuyan, Orth, Peter, Strickland, Corey O., Sun, Jing, Niu, Xiaoda, Chen, Shiying, Kozlowski, Joseph A., Lundell, Daniel J., Piwinski, John J., Shih, Neng-Yang, Siddiqui, M. Arshad

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Synthesis and SAR of pyridothiazole substituted pyrimidine derived HCV replication inhibitors von Girijavallabhan, Vinay M., Alvarez, Carmen, Bennett, Frank, Chen, Lei, Gavalas, Stephen, Huang, Yuhua, Kim, Seong-Heon, Kosinski, Aneta, Pinto, Patrick, Rizvi, Razia, Rossman, Randall, Shankar, Bandarpalle, Tong, Ling, Velazquez, Francisco, Venkatraman, Srikanth, Verma, Vishal A., Kozlowski, Joseph, Shih, Neng-Yang, Piwinski, John J., MacCoss, Malcolm, Kwong, Cecil D., Bansal, Namita, Clark, Jeremy L., Fowler, Anita T., Kezar, Hollis S., Valiyaveettil, Jacob, Reynolds, Robert C., Maddry, Joseph A., Ananthan, Subramaniam, Secrist, John A., Li, Cheng, Chase, Robert, Curry, Stephanie, Huang, Hsueh-Cheng, Tong, Xiao, Njoroge, F. George, Arasappan, Ashok

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The discovery of novel tartrate-based TNF-α converting enzyme (TACE) inhibitors von Rosner, Kristin E., Guo, Zhuyan, Orth, Peter, Shipps, Gerald W., Belanger, David B., Chan, Tin Yau, Curran, Patrick J., Dai, Chaoyang, Deng, Yongqi, Girijavallabhan, Vinay M., Hong, Liwu, Lavey, Brian J., Lee, Joe F., Li, Dansu, Liu, Zhidan, Popovici-Muller, Janeta, Ting, Pauline C., Vaccaro, Henry, Wang, Li, Wang, Tong, Yu, Wensheng, Zhou, Guowei, Niu, Xiaoda, Sun, Jing, Kozlowski, Joseph A., Lundell, Daniel J., Madison, Vincent, McKittrick, Brian, Piwinski, John J., Shih, Neng -Yang, Arshad Siddiqui, M., Strickland, Corey O.

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Novel TNF-α converting enzyme (TACE) inhibitors as potential treatment for inflammatory diseases von Girijavallabhan, Vinay M., Chen, Lei, Dai, Chaoyang, Feltz, Robert J., Firmansjah, Luke, Li, Dansu, Kim, Seong Heon, Kozlowski, Joseph A., Lavey, Brian J., Kosinski, Aneta, Piwinski, John J., Popovici-Muller, Janeta, Rizvi, Razia, Rosner, Kristin E., Shankar, Banderpalle B., Shih, Neng-Yang, Siddiqui, M. Arshad, Tong, Ling, Wong, Michael K.C., Yang, De-yi, Yang, Liping, Yu, Wensheng, Zhou, Guowei, Guo, Zhuyan, Orth, Peter, Madison, Vincent, Bian, Hong, Lundell, Daniel, Niu, Xiaoda, Shah, Himanshu, Sun, Jing, Umland, Shelby

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Structure and activity relationships of tartrate-based TACE inhibitors von Li, Dansu, Popovici-Muller, Janeta, Belanger, David B., Caldwell, John, Dai, Chaoyang, David, Maria, Girijavallabhan, Vinay M., Lavey, Brian J., Lee, Joe F., Liu, Zhidan, Mazzola, Rob, Rizvi, Razia, Rosner, Kristin E., Shankar, Bandarpalle, Spitler, Jim, Ting, Pauline C., Vaccaro, Henry, Yu, Wensheng, Zhou, Guowei, Zhu, Zhaoning, Niu, Xiaoda, Sun, Jing, Guo, Zhuyan, Orth, Peter, Chen, Shiying, Kozlowski, Joseph A., Lundell, Daniel J., Madison, Vincent, McKittrick, Brian, Piwinski, John J., Shih, Neng-Yang, Shipps, Gerald W., Siddiqui, M. Arshad, Strickland, Corey O.

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Desketoneoenactin-Siderophore Conjugates for Candida: Evidence of Iron Transport-Dependent Species Selectivity von BERNIER, Geneviève, GIRIJAVALLABHAN, Vinay, MURRAY, Aaron, NIYAZ, Noormohamed, PINGYU DING, MILLER, Marvin J, MALOUIN, Francois

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Novel intramolecular aminohydroxylation toward the syntheses of 2′-amino-2′-ethynyl nucleosides von Huang, Yuhua, Bennett, Frank, Buevich, Alexei, Girijavallabhan, Vinay, Kerekes, Angela D., Huang, Hsueh-Cheng, Tawa, Paul, Bogen, Stephane L., Davies, Ian W.

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The discovery of novel tartrate-based TNF-a converting enzyme (TACE) inhibitors von Rosner, Kristin E, Guo, Zhuyan, Orth, Peter, Shipps, Gerald W, Belanger, David B, Chan, Tin Yau, Curran, Patrick J, Dai, Chaoyang, Deng, Yongqi, Girijavallabhan, Vinay M, Hong, Liwu, Lavey, Brian J, Lee, Joe F, Li, Dansu, Liu, Zhidan, Popovici-Muller, Janeta, Ting, Pauline C, Vaccaro, Henry, Wang, Li, Wang, Tong, Yu, Wensheng, Zhou, Guowei, Niu, Xiaoda, Sun, Jing, Kozlowski, Joseph A, Lundell, Daniel J, Madison, Vincent, McKittrick, Brian, Piwinski, John J, Shih, Neng-Yang, Siddiqui, MArshad, Strickland, Corey O

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Fused bi-heteroaryl substituted hydantoin compounds as TACE inhibitors von Tong, Ling, Kim, Seong Heon, Rosner, Kristin, Yu, Wensheng, Shankar, Bandarpalle B., Chen, Lei, Li, Dansu, Dai, Chaoyang, Girijavallabhan, Vinay, Popovici-Muller, Janeta, Yang, Liping, Zhou, Guowei, Kosinski, Aneta, Siddiqui, M. Arshad, Shih, Neng-Yang, Guo, Zhuyan, Orth, Peter, Chen, Shiying, Lundell, Daniel, Niu, Xiaoda, Umland, Shelby, Kozlowski, Joseph A.

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Syntheses of nucleosides with a 1′,2′-β-lactam moiety as potential inhibitors of hepatitis C virus NS5B polymerase von Dang, Qun, Zhang, Zhibo, Bai, Yunfeng, Sun, Ruijun, Yin, Jie, Chen, Tongqian, Bogen, Stephane, Girijavallabhan, Vinay, Olsen, David B., Meinke, Peter T.

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Syntheses of 4′-spirocyclic phosphono-nucleosides as potential inhibitors of hepatitis C virus NS5B polymerase von Dang, Qun, Zhang, Zhibo, He, Shuangsheng, Liu, Yaohong, Chen, Tongqian, Bogen, Stephane, Girijavallabhan, Vinay, Olsen, David B., Meinke, Peter T.

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Syntheses of nucleosides with 2′-spirolactam and 2′-spiropyrrolidine moieties as potential inhibitors of hepatitis C virus NS5B polymerase von Dang, Qun, Zhang, Zhibo, Tang, Bingyu, Song, Yang, Wu, Ling, Chen, Tongqian, Bogen, Stephane, Girijavallabhan, Vinay, Olsen, David B., Meinke, Peter T.

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Development of a prodrug of hydantoin based TACE inhibitor von Tong, Ling, Kim, Seong Heon, Chen, Lei, Kosinski, Aneta, Shankar, Bandarpalle B., Girijavallabhan, Vinay, Yang, De-Yi, Yu, Wensheng, Zhou, Guowei, Shih, Neng-Yang, Chen, Shiying, Hu, Mengwei, Lundell, Daniel, Niu, Xiaoda, Umland, Shelby, Kozlowski, Joseph A.

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Concise syntheses and HCV NS5B polymerase inhibition of (2′R)-3 and (2′S)-2′-ethynyluridine-10 and related nucleosides von Bennett, Frank, Buevich, Alexei V., Huang, Hsueh-Cheng, Girijavallabhan, Vinay, Kerekes, Angela D., Huang, Yuhua, Malikzay, Asra, Smith, Elizabeth, Ferrari, Eric, Senior, Mary, Osterman, Rebecca, Wang, Lingyan, Wang, Jun, Pu, Haiyan, Truong, Quang T., Tawa, Paul, Bogen, Stephane L., Davies, Ian W., Weber, Ann E.

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Syntheses of 1′,2′-cyclopentyl nucleosides as potential antiviral agents von Dang, Qun, Zhang, Zhibo, Chen, Tongqian, Tang, Bingyu, He, Xinglin, He, Shuangsheng, Song, Yang, Bogen, Stephane, Girijavallabhan, Vinay, Olsen, David B., Meinke, Peter T.

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Novel methods to functionalize thiazolo[4,5- c]pyridines von Girijavallabhan, Vinay, Arasappan, Ashok, Bennett, Frank, Huang, Yuhua, George Njoroge, F., MacCoss, Malcolm

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5-Benzothiazole substituted pyrimidine derivatives as HCV replication (replicase) inhibitors von Arasappan, Ashok, Bennett, Frank, Girijavallabhan, Vinay, Huang, Yuhua, Huelgas, Regina, Alvarez, Carmen, Chen, Lei, Gavalas, Stephen, Kim, Seong-Heon, Kosinski, Aneta, Pinto, Patrick, Rizvi, Razia, Rossman, Randall, Shankar, Bandarpalle, Tong, Ling, Velazquez, Francisco, Venkatraman, Srikanth, Verma, Vishal A., Kozlowski, Joseph, Shih, Neng-Yang, Piwinski, John J., MacCoss, Malcolm, Kwong, Cecil D., Clark, Jeremy L., Fowler, Anita T., Geng, Feng, Kezar, Hollis S., Roychowdhury, Abhijit, Reynolds, Robert C., Maddry, Joseph A., Ananthan, Subramaniam, Secrist, John A., Li, Cheng, Chase, Robert, Curry, Stephanie, Huang, Hsueh-Cheng, Tong, Xiao, Njoroge, F. George

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Synthesis and SAR of geminal substitutions at the C5′ carbosugar position of pyrimidine-derived HCV inhibitors von Verma, Vishal A., Rossman, Randall, Bennett, Frank, Chen, Lei, Gavalas, Stephen, Girijavallabhan, Vinay, Huang, Yuhua, Kim, Seong-Heon, Kosinski, Aneta, Pinto, Patrick, Rizvi, Razia, Shankar, Bandarpalle, Tong, Ling, Velazquez, Francisco, Venkatraman, Srikanth, Kozlowski, Joseph, MacCoss, Malcolm, Kwong, Cecil D., Bansal, Namita, Kezar, Hollis S., Reynolds, Robert C., Maddry, Joseph A., Ananthan, Subramaniam, Secrist, John A., Li, Cheng, Chase, Robert, Curry, Stephanie, Huang, Hsueh-Cheng, Tong, Xiao, Njoroge, F. George, Arasappan, Ashok

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